ESR1 antibody
Applications Immunogen Background- Product Name
- ESR1 antibody
- Chemical Name
- ESR1 antibody
- Synonyms
- ESR1 antibody;Mouse Monoclonal ESR1 Antibody
- CBNumber
- CB95625821
- Formula Weight
- 0
- MOL File
- Mol file
ESR1 antibody Chemical Properties,Usage,Production
Applications
Western Blot, Immunofluorescent Staining, Immunohistochemistry, flow cytometry, immunoprecipitation.
Immunogen
Recombinant human ER-alpha.
Background
Estrogen receptors α (ERα, ER; NR3A1) is a member of the steroid hormone receptor family. ERα is a ligand-activated transcription factor. ERα contain DNA binding and ligand binding domains. ERα is expressed in a wide variety of tissues, including ovary, uterus, breast, prostate, testis, epididymis, bones, bladder, kidney, heart, vessel wall, pituitary gland and hypothalamus. ER plays a variety of important roles in the maintenance of the reproductive, cardiovascular, musculoskeletal and central nervous systems. The natural ligand for ER is 17β-estradiol, the classical estrogenic compound. The binding of estrogen to ER induces a conformational change and triggers a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes.
ESR1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
ESR1 antibody Suppliers
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