PDI antibody
Source Reactivity Background References- Product Name
- PDI antibody
- Chemical Name
- PDI antibody
- Synonyms
- PDI antibody;Rabbit Monoclonal PDI Antibody
- CBNumber
- CB95671237
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb379096
- Product name
- PDI antibody
- Purity
- Peptide affinity purified
- Packaging
- 100μL
- Price
- $399.5
- Updated
- 2021/12/16
- Product number
- orb11258
- Product name
- PDI antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
PDI antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Background
During their synthesis, secretory proteins translocate into the endoplasmic reticulum where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds. This process is called oxidative protein folding. Protein disulfide isomerase catalyzes the formation and isomerization of these disulfide bonds. Studies on mechanisms of oxidative folding suggest that molecular oxygen oxidizes the ER-protein Ero1, which in turn oxidizes PDI through disulfide exchange. This event is then followed by PDI-catalyzed disulfide bond formation in folding proteins.
References
[1] Huppa, J.B. and Ploegh, H.L. (1998) Cell 92, 145-148.
[2] Ellgaard, L. and Ruddock, L.W. (2005) EMBO Rep. 6, 28-32.
[3] Tu, B.P. and Weissman, J.S. (2004) J. Cell Biol. 164, 341-346.
PDI antibody Preparation Products And Raw materials
Raw materials
Preparation Products
PDI antibody Suppliers
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