ZO 1 Antibody
Source Reactivity Background References- Product Name
- ZO 1 Antibody
- Chemical Name
- ZO 1 Antibody
- Synonyms
- ZO 1 Antibody
- CBNumber
- CB95706573
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb379329
- Product name
- ZO1 antibody
- Purity
- Peptide affinity purified
- Packaging
- 100μL
- Price
- $399.5
- Updated
- 2021/12/16
- Product number
- orb499602
- Product name
- ZO-1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb499587
- Product name
- ZO-1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb500468
- Product name
- ZO-1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb499602
- Product name
- ZO-1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
ZO 1 Antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Monkey
Background
Tight junctions, or zona occludens, form a continuous barrier to fluids across the epithelium and endothelium. They function in regulation of paracellular permeability and in the maintenance of cell polarity, blocking the movement of transmembrane proteins between the apical and the basolateral cell surfaces. ZO-1, -2, and -3 are peripheral membrane adaptor proteins that link junctional transmembrane proteins, such as occludin and claudin, to the actin cytoskeleton. ZO-1 and ZO-2 are required for tight junction formation and function. In subconfluent proliferating cells, ZO-1 and ZO-2 have been shown to colocalize to the nucleus and play a role in transcriptional regulation, possibly through facilitating nuclear import/export of transcriptional regulators. The ZO-2 gene is transcribed from two promoters, generating the ZO-2A and ZO-2C isoforms. ZO-2C lacks a 23 amino acid amino-terminal sequence found in other ZO-2 isoforms. While both isoforms appear to be widely expressed, abnormal regulation of the ZO-2 gene may be correlated with development of ductal cancer.
References
[1] Shin, K. et al. (2006) Annu Rev Cell Dev Biol 22, 207-35.
[2] Matter, K. and Balda, M.S. (2007) J Cell Sci 120, 1505-11.
[3] Hernandez, S. et al. (2007) Exp Cell Res 313, 1533-47.
[4] Umeda, K. et al. (2006) Cell 126, 741-754.
[5] Betanzos, A. et al. (2004) Exp Cell Res 292, 51-66.
[6] Traweger, A. et al. (2003) J Biol Chem 278, 2692-700.
[7] Huerta, M. et al. (2007) Mol Biol Cell 18, 4826-36.
[8] Chlenski, A. et al. (2000) Biochim Biophys Acta 1493, 319-24.
ZO 1 Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
ZO 1 Antibody Suppliers
- Tel
- 18007124176
- ipdshengwu@163.com
- Country
- China
- ProdList
- 4801
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- 58
- Tel
- 0755-26755892 1-949-553-1900
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- China
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- 858.663.9055 8586639055
- NSJBioname@qq.com
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- China
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- 6941
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- Tel
- Enzo Biochem Inc. 13797054060
- Enzoname@qq.com
- Country
- China
- ProdList
- 6174
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- 58
- Tel
- 18886812933
- sales@biosynth.com
- Country
- China
- ProdList
- 6218
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- 21-80243558 86218024
- info@cellsignal.cn
- Country
- China
- ProdList
- 6427
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- 1-+1 484.791.3823 14847913823
- orders@rockland.com
- Country
- China
- ProdList
- 4881
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- Tel
- 4006-123-828 13162017139
- market@ab-mart.com
- Country
- China
- ProdList
- 6917
- Advantage
- 58
- Tel
- 025-58868422
- info@sabbiotech.com
- Country
- China
- ProdList
- 6243
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- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58