ChemicalBook > CAS DataBase List > 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
- Product Name
- 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
- CAS No.
- 16616-39-0
- Chemical Name
- 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
- Synonyms
- MLS-532223;MLS000532223;MLS000532223, 10 mM in DMSO;1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one;1-(3-Nitrophenyl)-3-phenylprop-2-yn-1-one;2-Propyn-1-one, 1-(3-nitrophenyl)-3-phenyl-;GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GTPases,Ras,inhibit
- CBNumber
- CB96188330
- Molecular Formula
- C15H9NO3
- Formula Weight
- 251.24
- MOL File
- 16616-39-0.mol
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1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Property
- Melting point:
- 120-121 °C
- Boiling point:
- 419.6±47.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- RT (des.)
- solubility
- Soluble in DMSO (up to 20 mg/ml).
- form
- solid
- color
- Beige
- Stability:
- Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0064006
- Product name
- MLS000532223
- Purity
- 99.47%
- Packaging
- 5mg
- Price
- $400
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0064006
- Product name
- MLS000532223
- Purity
- 99.47%
- Packaging
- 10mg
- Price
- $600
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0064006
- Product name
- MLS000532223
- Purity
- 99.47%
- Packaging
- 50mg
- Price
- $1800
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN27587
- Product name
- MLS000532223
- Packaging
- 5mg
- Price
- $372
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN27587
- Product name
- MLS000532223
- Packaging
- 50mg
- Price
- $1674
- Updated
- 2021/12/16
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1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Chemical Properties,Usage,Production
Description
MLS-532223 (16616-39-0) is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable.
Uses
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 values ranging from 16 μM to 120 μM. MLS000532223 prevents GTP binding to several GTPases[1].
Definition
ChEBI: 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one is an aromatic compound.
References
[1] ZURAB SURVILADZE . Identification of a Small GTPase Inhibitor Using a High-Throughput Flow Cytometry Bead-Based Multiplex Assay[J]. SLAS Discovery, 2010, 15 1: Pages 10-20. DOI:10.1177/1087057109352240
1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Preparation Products And Raw materials
Raw materials
Preparation Products
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1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Suppliers
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