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Dolutegravir Impurity C

Product Name
Dolutegravir Impurity C
CAS No.
1802141-49-6
Chemical Name
Dolutegravir Impurity C
Synonyms
Dolutegravir Impurity 20;Dolutegravir Impurity 23;Dolutegravir Impurity 32;Syringaresinol Impurity 1(Syringaresinol Diglucoside);(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:;(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber
CB96222324
Molecular Formula
C22H23F2N3O5
Formula Weight
447.43
MOL File
1802141-49-6.mol
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Dolutegravir Impurity C Property

Boiling point:
688.1±55.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
pka
10.71±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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Dolutegravir Impurity C Chemical Properties,Usage,Production

Uses

O-Ethyl Dolutegravir is an impurity of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity C Preparation Products And Raw materials

Raw materials

Preparation Products

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Dolutegravir Impurity C Suppliers

Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.
Tel
020-89854820
Email
sales@jzpharma.cn
Country
China
ProdList
1130
Advantage
58
Molcoo Chemicals Inc.
Tel
18627756402
Email
3001051413@qq.com
Country
China
ProdList
9544
Advantage
58
Shenzhen Roark Pharma-Tec Co., Ltd.
Tel
13128912434
Email
2880126944@qq.com
Country
China
ProdList
2577
Advantage
58
guoyungurui
Tel
18162595016; 18162595016
Email
3287908757@qq.com
Country
China
ProdList
10336
Advantage
58
ShenZhen H&D Pharmaceutical Technology Co., LTD
Tel
18672472998
Email
sunchenjie@hdimpurity.com
Country
China
ProdList
6906
Advantage
58

1802141-49-6, Dolutegravir Impurity CRelated Search:


  • Dolutegravir Impurity 20
  • (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:
  • Dolutegravir Impurity 23
  • (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
  • Dolutegravir Impurity 32
  • Syringaresinol Impurity 1(Syringaresinol Diglucoside)
  • 1802141-49-6