Dolutegravir Impurity C

Product Name: Dolutegravir Impurity C
CAS No.: 1802141-49-6
Chemical Name: Dolutegravir Impurity C
Synonyms: O-Ethyl Dolutegravir;Durutevir impurity 23;Dolutegravir Impurity 20;Dolutegravir Impurity 23;Dolutegravir Impurity 32;Syringaresinol Impurity 1(Syringaresinol Diglucoside);(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:;(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber: CB96222324
Molecular Formula: C22H23F2N3O5
Formula Weight: 447.43
MOL File: 1802141-49-6.mol

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Dolutegravir Impurity C Property

Boiling point:: 688.1±55.0 °C(Predicted)
Density: 1.42±0.1 g/cm3(Predicted)
pka: 10.71±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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Dolutegravir Impurity C Chemical Properties,Usage,Production

Uses

O-Ethyl Dolutegravir is an impurity of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity C Preparation Products And Raw materials

Raw materials

Preparation Products

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Dolutegravir Impurity C Suppliers

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Daicel Chiral Technologies (China)CO.,LTD

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1802141-49-6, Dolutegravir Impurity CRelated Search:

Dolutegravir Impurity 18 Dolutegravir Impurity 19 Dolutegravir Impurity 8 Dolutegravir Impurity 7 Dolutegravir SR Isomer Dolutegravir Impurity 21 Dolutegravir Impurity 8 Dolutegravir Impurity 13(Sodium Salt) Dolutegravir Impurity 6 Dolutegravir Impurity 15 Dolutegravir Glucuronide Dolutegravir Impurity 22 Dolutegravir Impurity 14(Sodium Salt) Dolutegravir Glucoside Duluvir impurity 1 Dolutegravir Impurity 24

Dolutegravir Impurity 20

(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:

Dolutegravir Impurity 23

(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-

Dolutegravir Impurity 32

Syringaresinol Impurity 1(Syringaresinol Diglucoside)

Durutevir impurity 23

O-Ethyl Dolutegravir

1802141-49-6