Synthesis
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BETA-GLUCAN

Synthesis
Product Name
BETA-GLUCAN
CAS No.
9008-22-4
Chemical Name
BETA-GLUCAN
Synonyms
CURDLAN;Lamiran;Iodus 40;LAMINARIN;PARAMYLON;LAMINARAN;LamMnarMn;Goemar H 11;β-1,3-Gulucan;LaMinaran 
CBNumber
CB9683840
Molecular Formula
C18H30O14X2
Formula Weight
470.42
MOL File
9008-22-4.mol
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BETA-GLUCAN Property

Melting point:
>220°C (dec.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 20 mg/mL, clear, faintly yellow
form 
powder
color 
White to Off-white
Water Solubility 
Soluble in dimethyl sulfoxide (slightly, heated). Slightly soluble in water.
Merck 
14,5350
LogP
-6.080 (est)
EPA Substance Registry System
Laminaran (9008-22-4)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
LZ3985000
3
TSCA 
Yes
HS Code 
39139000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L9634
Product name
Laminarin from Laminaria digitata
Purity
polysaccharide substrate for laminarinase
Packaging
1g
Price
$179
Updated
2024/03/01
Sigma-Aldrich
Product number
L9634
Product name
Laminarin from Laminaria digitata
Purity
polysaccharide substrate for laminarinase
Packaging
5g
Price
$683
Updated
2024/03/01
TCI Chemical
Product number
L0088
Product name
Laminaran from Eisenia Bicyclis
Packaging
1g
Price
$56
Updated
2024/03/01
TCI Chemical
Product number
L0088
Product name
Laminaran from Eisenia Bicyclis
Packaging
25g
Price
$408
Updated
2024/03/01
Alfa Aesar
Product number
J66193
Product name
Laminarin
Packaging
1g
Price
$118
Updated
2024/03/01
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BETA-GLUCAN Chemical Properties,Usage,Production

Synthesis

1. Extraction process: kelp powder → leaching → centrifugation → taking supernatant → low temperature evaporation and concentration to 1/4 of the original volume → 95% ethanol precipitation → ether degreasing → acetone decolorization → absolute ethanol washing → vacuum freeze drying → Kombu Crude Polysaccharide.
2. Purification method: add water to dissolve kelp crude polysaccharide, and adjust the pH value to 8 with ammonia water; under the condition that the temperature is lower than 50 ℃, add 20% H2O2 dropwise until the solution is pale yellow, and then keep it for 2 hours; Distilled water was dialyzed for 3 d. After 3 d, the non-permeable part was removed by Sevag method; then dialyzed with distilled water for 3 d, added 3 times the volume of 95% ethanol for precipitation, and left standing at 4 °C overnight; centrifuged the next day, and collected the precipitate. Preliminary purified white fibrous kelp polysaccharide can be obtained by vacuum freeze-drying.
3. Extraction and purification: Weigh kelp coarse powder and place it in a round-bottomed flask, add petroleum ether (60-90°C) to soak for 2 hours; reflux extraction for 1 hour, filter; evaporate the filter residue to dry the solvent, and extract twice with 95% ethanol under reflux , filtered for 1 h each time; the filter residue was placed in a round-bottomed flask, soaked in distilled water for 1 h, refluxed for 2 h, and filtered; then distilled water was added for reflux extraction for 2 h, filtered; the filtrates were combined, concentrated to an appropriate amount, and the protein was removed by the Sevage method. 95% ethanol was added to make the alcohol content 80%, left standing overnight, and suction filtered; the filter residue was washed several times with absolute ethanol and acetone in turn to obtain the refined polysaccharide.

Description

Laminarin mainly includes brown algae (such as sodium alginate, also known as alginate, the content in kelp is about 19.7%), fucoidan (also known as laminarin, seaweed sulfate polysaccharide, fucoidan, the content in kelp is about 1%), Fucoidan (also known as fucoidan, the main component is fucoidan, also known as fucoidan) and other 3 types, consisting of β(1-3)-glucan and some β(1-6)- Composed of glycosidic bonds, it is a kind of neutral glucan, widely present in brown algae, and also the main chemical component in kelp of the family Pterophyceaceae or kelp of the kelp family. It has the functions of regulating immunity, anti-tumor, anti-coagulation, regulating blood lipids. , hypoglycemic, anti-radiation, antioxidant, antibacterial, antiviral and other pharmacological effects, but also has various effects such as lowering blood pressure, fatigue resistance, anti-pulmonary fibrosis, regulating tyrosine kinase activity, and anti-mutation.

Chemical Properties

laminarinase substrate

Physical properties

The dry crude polysaccharide product is a yellow-brown lumpy solid with a fishy smell of sea. Decolorized by H2O2 and freeze-dried to obtain a white fibrous solid, soluble in water, easily soluble in hot water, insoluble in acid and alkali, insoluble in high-concentration ethanol, methanol, acetone and other organic solvents, non-volatile, pH 6.5 , the specific rotation is [α]D20=-1.25°(c=0.80, H2O).

Occurrence

Kombu, also known as kelp, seaweed, sea kelp, sea cabbage. Extracted from the thallus of Laminaria japonica Aresch. and Ecklonia kurome Okam.

Uses

Laminarin is a storage glucan and is now used to study it?s interaction with laminarinase as its substrate.

Definition

Laminarin obtained from Laminaria digitata. It is a .beta.-(1-3)-linked D-glucan with .BETA.-(1-6) linkages. The major M-series contains 20-30 glucosyl residues linked to terminal mannitol, and a minor G-series with 22-28 glucosyl residues. There is a 3 to 1 ratio of M-series to G-series molecules. There is an average of 1.3 branches per molecule.

General Description

The fronds of Laminaria and Saccharina species contain laminarin, a low molecular weight storage glucan. It is localized to the vacuoles. Laminarin structure contains β-(1,6)-intrachain linked (1,3)-β-d-glucan.

Biochem/physiol Actions

Laminarin is a polysaccharide of glucose found in brown algae and utilized as a food reserve.

BETA-GLUCAN Preparation Products And Raw materials

Raw materials

Preparation Products

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BETA-GLUCAN Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18736
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4531
Advantage
62
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View Lastest Price from BETA-GLUCAN manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
BETA-GLUCAN; Kelp Polysaccharides 9008-22-4
Price
US $0.00/KG
Min. Order
1KG
Purity
30%; 50%; 80% HPLC
Supply Ability
1000KG
Release date
2022-09-28
Hebei Yanxi Chemical Co., Ltd.
Product
BETA-GLUCAN 9008-22-4
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-16
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Laminaran from Eisenia Bicyclis 9008-22-4
Price
US $0.00/G
Min. Order
10G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-14

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