beta-d-Glucan, (1->3),(1->6)-
- Product Name
- beta-d-Glucan, (1->3),(1->6)-
- CAS No.
- 53238-80-5
- Chemical Name
- beta-d-Glucan, (1->3),(1->6)-
- Synonyms
- S 4001;Antivir;Imuneks;Immutol;Agrastim;Gluimmun;Glucanil;Glucan P;Aqua-beta;Macrogard
- CBNumber
- CB9904800
- Formula Weight
- 0
- MOL File
- Mol file
beta-d-Glucan, (1->3),(1->6)- Property
- form
- Solid
- color
- White to off-white
Safety
- HS Code
- 3913900099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- NUT0000167
- Product name
- BETA-D-GLUCAN, 1,3-1,6
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.75
- Updated
- 2021/12/16
beta-d-Glucan, (1->3),(1->6)- Chemical Properties,Usage,Production
Uses
Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response[1][2].
in vivo
Odetiglucan (1.2 mg, i.v., once a week, 3 weeks) inhibits the proliferation of cancer cells and triggers an effective T cell-mediated response against liver metastases in a mouse model of pancreatic cancer[1].
| Animal Model: | Pancreatic Ductal Adenocarcinoma (PDAC) mouse model[1] |
| Dosage: | 1.2 mg; once a week; 3 weeks |
| Administration: | Intravenous injection (i.v.) |
| Result: | Activated liver-resident macrophages, inhibited cancer cell proliferation, and drived T cell activation and macrophage repolarization in mouse liver metastases. |
References
[1] Stacy K Thomas, et al. Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice. Nat Commun. 2023 Oct 10;14(1):6330. DOI:10.1038/s41467-023-41771-z
[2] WHO Drug Information. International Nonproprietary Names for Pharmaceutical
beta-d-Glucan, (1->3),(1->6)- Preparation Products And Raw materials
Raw materials
Preparation Products
beta-d-Glucan, (1->3),(1->6)- Suppliers
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- +8618058761490
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View Lastest Price from beta-d-Glucan, (1->3),(1->6)- manufacturers
- Product
- beta-d-Glucan, (1->3),(1->6)- 53238-80-5
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-23