AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH
- Product Name
- AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH
- CAS No.
- 106128-98-7
- Chemical Name
- AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH
- Synonyms
- AC-ASQKRPSQRHG;MBP (1-11) HUMAN;ACETYL-MBP (135-145) (HUMAN);AC-MBP (HUMAN, PORCINE, RAT 1-11);MYELIN BASIC PROTEIN (135-145), HUMAN;ACETYL-GOLLI-MBP1 HOG7 (135-145) (HUMAN);ACETYL-MYELIN A1 PROTEIN (135-145) (HUMAN);Acetyl-Myelin Basic Protein (135-145)) (hu;MBP (1-11), GUINEA PIG, PORCINE, RABBIT, RAT;ACETYL-MYELIN BASIC PROTEIN (135-145) (HUMAN)
- CBNumber
- CB9688340
- Molecular Formula
- C52H88N22O17
- Formula Weight
- 1293.39
- MOL File
- 106128-98-7.mol
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH Property
- Density
- 1.59±0.1 g/cm3(Predicted)
- pka
- 3.19±0.10(Predicted)
- form
- Solid
- Water Solubility
- Soluble in water
N-Bromosuccinimide Price
- Product number
- PEP0002444
- Product name
- MBP (1 - 11), GUINEA PIG, PORCINE, RABBIT, RAT, MYELIN BASIC PROTEIN (135 - 145), HUMAN
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $745.85
- Updated
- 2021/12/16
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH Chemical Properties,Usage,Production
Uses
Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE)[1][2].
in vivo
Myelin Basic Protein (1-11) (100 μg/mL)-pulsed DC cells (i.p.) leads to experimental autoimmune encephalomyelitis (EAE) when transferred into irradiated B10.PL mice[1].
Myelin Basic Protein (1-11) (100 μg, i.p.) induced tolerance to MBP in adult mice and prevents MBP-induced EAE[2].
References
[1] Dittel BN, et al. Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis. J Immunol. 1999 Jul 1;163(1):32-9. PMID:10384096
[2] Gaur A, et al. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science. 1992 Nov 27;258(5087):1491-4. DOI:10.1126/science.1279812
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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