OLEYLOXYETHYL PHOSPHORYLCHOLINE

Product Name: OLEYLOXYETHYL PHOSPHORYLCHOLINE
CAS No.: 84601-19-4
Chemical Name: OLEYLOXYETHYL PHOSPHORYLCHOLINE
Synonyms: NPLMVGGTFDUQHL-SEYXRHQNSA-N;OLEYLOXYETHYLPHOSPHOCHOLINE;OLEYOXYETHYL PHOSPHORYLCHOLINE;OLEYLOXYETHYL PHOSPHORYLCHOLINE;(Z)-Oleyloxyethyl phosphorylcholine;PHOSPHORYLCHOLINE, OLEOYLOXYETHYL ESTER;OLEYLOXYETHYL PHOSPHORYLCHOLINE USP/EP/BP;Oleyloxyethyl Phosphorylcholine in Solution;1-O-9Z-OCTADECENYLETHYLENEGLYCOL-2-O-PHOSPHORYLCHOLINE;(17Z)-4-Hydroxy-N,N,N-trimethyl-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium inner salt 4-oxide
CBNumber: CB9700152
Molecular Formula: C25H52NO5P
Formula Weight: 477.67
MOL File: 84601-19-4.mol

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OLEYLOXYETHYL PHOSPHORYLCHOLINE Property

storage temp.: -20°C
solubility: ≤16mg/ml in DMSO;16mg/ml in dimethyl formamide
form: solution in ethanol.
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 70560
Product name: Oleyloxyethyl Phosphorylcholine
Purity: ≥98%
Packaging: 1mg
Price: $12
Updated: 2024/03/01

Cayman Chemical

Product number: 70560
Product name: Oleyloxyethyl Phosphorylcholine
Purity: ≥98%
Packaging: 5mg
Price: $45
Updated: 2024/03/01

Cayman Chemical

Product number: 70560
Product name: Oleyloxyethyl Phosphorylcholine
Purity: ≥98%
Packaging: 10mg
Price: $79
Updated: 2024/03/01

Cayman Chemical

Product number: 70560
Product name: Oleyloxyethyl Phosphorylcholine
Purity: ≥98%
Packaging: 50mg
Price: $341
Updated: 2024/03/01

ApexBio Technology

Product number: C3792
Product name: OleyloxyethylPhosphorylcholine
Packaging: 50mg(solution)
Price: $389
Updated: 2021/12/16

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OLEYLOXYETHYL PHOSPHORYLCHOLINE Chemical Properties,Usage,Production

Description

Oleyloxyethyl phosphorylcholine is an inhibitor of PLA₂ with an IC₅₀ value of 6.2 μM for porcine pancreatic PLA₂.

Uses

(Z)-Oleyloxyethyl phosphorylcholine ((Z)-OPC) is an isomer of Oleyloxyethyl phosphorylcholine (OPC). Oleyloxyethyl phosphorylcholine is an inhibitor of secreted Phospholipase A2 (sPLA2), which is involved in the biosynthesis of proinflammatory lipid media. Oleyloxyethyl phosphorylcholine can be used to study inflammatory diseases. Oleyloxyethyl phosphorylcholine also modified the red blood membrane and was used to bind the oxygen-carrying liquid perfluorocarbons as an antivenom agent to reduce toxin-induced hemolysis[1][2].

in vitro

to examine the phospholipids including oleyloxyethyl phosphorylcholine as pla2 inhibitors, the enzyme assay was employed. determinations were performed below critical micelle concentration. porcine pancreatic pla2 and phospholipid inhibitor were preincubated for 2 min at 37°c in buffer at ph 8.5. introduction of [l4c]arachidonate phosphatidylcholine initiated the enzymatic reaction, which is quenched after 5 min at 37°c. in this manner 50% inhibitor concentrations were determined for mepacrine and alkylphosphorylcholines, indicating oleyloxyethyl phosphorylcholine was an inhibitor of pla2 with an ic50 of 6.2 μm for porcine pancreatic pla2 [1].

IC 50

6.2 μm for porcine pancreatic pla2

References

[1] magolda, r. l.,ripka, w.c.,galbraith, w., et al. novel synthesis of potent site-specific phospholipase a2 inhibitors. book: prostaglandins, leukotrienes and lipoxins 669-676 (1985).

OLEYLOXYETHYL PHOSPHORYLCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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OLEYLOXYETHYL PHOSPHORYLCHOLINE Suppliers

China 23 Switzerland 1 United Kingdom 1 United States 5 Global 30

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
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ChemStrong Scientific Co.,Ltd

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Shijiazhuang Gantuo Biotechnology Co., Ltd

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Shanghai Yifei Biotechnology Co. , Ltd.

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Nantong Hanfang Biotechnology Co. , Ltd.

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Chengdu Peter-like Biotechnology Co., Ltd.

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View Lastest Price from OLEYLOXYETHYL PHOSPHORYLCHOLINE manufacturers

Shijiazhuang Gantuo Biotechnology Co., Ltd

Product: Oleyloxyethyl Phosphorylcholine 84601-19-4
Price: US $100.00/mg
Min. Order: 10mg
Purity: 99%
Supply Ability: 1000g
Release date: 2023-03-10

Shijiazhuang Gantuo Biotechnology Co., Ltd

Product: Oleyloxyethyl Phosphorylcholine 84601-19-4
Price: US $100.00/mg
Min. Order: 10mg
Purity: 98%
Supply Ability: 1000g
Release date: 2023-03-24

Dideu Industries Group Limited

Product: OLEYLOXYETHYL PHOSPHORYLCHOLINE 84601-19-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-27

84601-19-4, OLEYLOXYETHYL PHOSPHORYLCHOLINERelated Search:

Choline glycerophosphate phosphorylcholine L-Α-GLYCEROPHOSPHORYL CHOLINE, CADMIUM CHLORIDE COMPLEX OLEYLOXYETHYL PHOSPHORYLCHOLINE Calcium phosphorylcholine chloride 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine OLEYLOXYETHYL PHOSPHORYLCHOLINE 1-TETRADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE 1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine L-3-PHOSPHATIDYLCHOLINE,1-PALMITOYL-2-[1-14C]OLEOYL PHOSPHATIDYLCHOLINE, L-ALPHA-DIOLEOYL, [DIOLEOYL-1-14C]

1-O-9Z-OCTADECENYLETHYLENEGLYCOL-2-O-PHOSPHORYLCHOLINE

PHOSPHORYLCHOLINE, OLEOYLOXYETHYL ESTER

OLEYLOXYETHYLPHOSPHOCHOLINE

OLEYLOXYETHYL PHOSPHORYLCHOLINE

OLEYOXYETHYL PHOSPHORYLCHOLINE

(17Z)-4-Hydroxy-N,N,N-trimethyl-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium inner salt 4-oxide

NPLMVGGTFDUQHL-SEYXRHQNSA-N

OLEYLOXYETHYL PHOSPHORYLCHOLINE USP/EP/BP

(Z)-Oleyloxyethyl phosphorylcholine

Oleyloxyethyl Phosphorylcholine in Solution

84601-19-4

C25H50NO6P

C25H52NO5P