5-BROMO-6-METHOXYPYRIDIN-2-AMINE

Product Name: 5-BROMO-6-METHOXYPYRIDIN-2-AMINE
CAS No.: 1211533-83-3
Chemical Name: 5-BROMO-6-METHOXYPYRIDIN-2-AMINE
Synonyms: 5-BROMO-6-METHOXYPYRIDIN-2-AMINE;5-Bromo-6-methoxy-2-pyridinamine;2-Pyridinamine, 5-bromo-6-methoxy-;5-Bromo-6-methoxy-pyridin-2-ylamine
CBNumber: CB9701977
Molecular Formula: C6H7BrN2O
Formula Weight: 203.04
MOL File: Mol file

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5-BROMO-6-METHOXYPYRIDIN-2-AMINE Property

storage temp.: Keep in dark place,Inert atmosphere,Room temperature
Appearance: Light yellow to green yellow Solid
InChI: InChI=1S/C6H7BrN2O/c1-10-6-4(7)2-3-5(8)9-6/h2-3H,1H3,(H2,8,9)
InChIKey: STTFWVSVDMLUCF-UHFFFAOYSA-N
SMILES: C1(N)=NC(OC)=C(Br)C=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B679503
Product name: 5-Bromo-6-methoxypyridin-2-amine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0354650
Product name: 2-AMINO-5-BROMO-6-METHOXYPYRIDINE
Purity: 95.00%
Packaging: 250MG
Price: $297.15
Updated: 2021/12/16

Ambeed

Product number: A238856
Product name: 5-Bromo-6-methoxypyridin-2-amine
Purity: 98%
Packaging: 250mg
Price: $42
Updated: 2021/12/16

Ambeed

Product number: A238856
Product name: 5-Bromo-6-methoxypyridin-2-amine
Purity: 98%
Packaging: 1g
Price: $94
Updated: 2021/12/16

Chemcia Scientific

Product number: CC00-9896
Product name: 5-Bromo-6-methoxy-pyridin-2-ylamine
Purity: 95%
Packaging: 0.5g
Price: $135
Updated: 2021/12/16

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5-BROMO-6-METHOXYPYRIDIN-2-AMINE Chemical Properties,Usage,Production

Synthesis

67-56-1

89284-11-7

1211533-83-3

The general procedure for the synthesis of 2-amino-5-bromo-6-methoxypyridine from methanol and 5,6-dibromopyridin-2-amine was as follows: sodium metal (1.8 g, 78.2 mmol) was added in small portions to dry methanol (70 mL) at -20 °C. The resulting solution was stirred at 0 °C for 4 hours. Subsequently, the reaction mixture was transferred to a sealed tube, 5,6-dibromopyridin-2-amine (Example 7a, 10 g, 39.8 mmol) was added and heated at 120 °C for 24 hours. After completion of the reaction, the solvent was removed under reduced pressure and the residue was diluted with water. The aqueous phase was neutralized with 2 M HCl and then extracted with ethyl acetate (3 x 100 mL). The organic phases were combined, dried with magnesium sulfate, filtered and concentrated in vacuum. The residue was purified by fast column chromatography using a gradient elution with a hexane solution of 5% to 15% acetone to afford the target product 2-amino-5-bromo-6-methoxypyridine (6.6 g, 82% yield). The product was confirmed by 1H NMR (400 MHz, CDCl3): δ 3.91 (s, 3H), 4.31 (br. s., 2H), 5.99 (d, 1H), 7.48 (d, 1H). esms m/z 202.8, 204.8 [M + H]+.

References

[1] Patent: US2012/122843, 2012, A1. Location in patent: Page/Page column 15
[2] Patent: WO2015/109109, 2015, A1. Location in patent: Paragraph 0711
[3] Patent: US2017/44182, 2017, A1. Location in patent: Paragraph 0983

5-BROMO-6-METHOXYPYRIDIN-2-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-6-METHOXYPYRIDIN-2-AMINE Suppliers

China 74 India 1 United States 5 Global 80

Nanijing m&m biotechnology Co. ,Ltd.

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Mashilabs (Shanghai) Co.,Ltd.

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Xi'an NewProChem Co.,Ltd.

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1211533-83-3, 5-BROMO-6-METHOXYPYRIDIN-2-AMINERelated Search:

Methyl 5-broMo-6-Methoxypicolinate 3-PYRIDINECARBONITRILE, 5-BROMO-6-METHOXY- METHYL 6-AMINO-5-BROMONICOTINATE 5-BroMo-6-Methoxy-nicotinic acid 5-Bromo-6-methoxypyridine-2-carboxylic acid 5-Bromo-6-methoxynicotinic acid methyl ester

5-BROMO-6-METHOXYPYRIDIN-2-AMINE

5-Bromo-6-methoxy-pyridin-2-ylamine

2-Pyridinamine, 5-bromo-6-methoxy-

5-Bromo-6-methoxy-2-pyridinamine

1211533-83-3