ChemicalBook > CAS DataBase List > Boc-Dap-OH

Boc-Dap-OH

Product Name
Boc-Dap-OH
CAS No.
73259-81-1
Chemical Name
Boc-Dap-OH
Synonyms
BOC-L-DAP-OH;(S)-3-AMINO-2-(TERT-BUTOXYCARBONYLAMINO)PROPANOIC ACID;BOC-L-DAP;BOC-DPR-OH;BOC-DAP-OH;Boc-Dapa-OH;BOC-L-DAPA-OH;(N-Boc-β-amino)-AL;3-Amino-Boc-L-alanin;Boc-Dap-OH USP/EP/BP
CBNumber
CB9715251
Molecular Formula
C8H16N2O4
Formula Weight
204.22
MOL File
73259-81-1.mol
More
Less

Boc-Dap-OH Property

Melting point:
210 °C (dec.)
alpha 
-5.5 º (c=1, acetic acid)
Boiling point:
364.4±37.0 °C(Predicted)
Density 
1.189±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO (Slightly, Heated, Sonicated), Water (Sparingly, Heated, Sonicated)
form 
Solid
pka
2.88±0.16(Predicted)
color 
White to Off-White
optical activity
[α]20/D +5.5±1°, c = 1% in methanol: water (1:1)
BRN 
4182136
InChI
InChI=1S/C8H16N2O4/c1-8(2,3)14-7(13)10-5(4-9)6(11)12/h5H,4,9H2,1-3H3,(H,10,13)(H,11,12)/t5-/m0/s1
InChIKey
KRJLRVZLNABMAT-YFKPBYRVSA-N
SMILES
C(O)(=O)[C@H](CN)NC(OC(C)(C)C)=O
CAS DataBase Reference
73259-81-1(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
24/25
WGK Germany 
3
F 
10
HazardClass 
IRRITANT
HS Code 
29241990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H260In contact with water releases flammable gases which may ignite spontaneously

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

H336May cause drowsiness or dizziness

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.

P231+P232Handle under inert gas. Protect from moisture.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P308+P313IF exposed or concerned: Get medical advice/attention.

P335+P334Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P402+P404Store in a dry place. Store in a closed container.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
15402
Product name
Boc-Dap-OH
Purity
≥98.0% (TLC)
Packaging
1g
Price
$86.8
Updated
2024/03/01
Sigma-Aldrich
Product number
15402
Product name
Boc-Dap-OH
Purity
≥98.0% (TLC)
Packaging
5g
Price
$390
Updated
2024/03/01
TCI Chemical
Product number
A2470
Product name
(S)-3-Amino-2-(tert-butoxycarbonylamino)propionic Acid
Purity
>95.0%(HPLC)(T)
Packaging
1g
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
A2470
Product name
(S)-3-Amino-2-(tert-butoxycarbonylamino)propionic Acid
Purity
>95.0%(HPLC)(T)
Packaging
5g
Price
$72
Updated
2024/03/01
Alfa Aesar
Product number
H26919
Product name
N(alpha)-Boc-L-2,3-diaminopropionic acid, 97%
Packaging
1g
Price
$63.65
Updated
2024/03/01
More
Less

Boc-Dap-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Reactant for:

  • Protein assembly directed by synthetic molecular recognition motifs
  • Solid phase synthesis of gramicidin S cyclic analogs with antibiotic and hemolytic activities
  • Synthesis of HCV protease inhibitor modified analogs
  • Solid phase synthesis of peptidic V1a receptor agonists
  • Directed peptide assembly at lipid-water interface

Uses

(S)-3-amino-2-(tert-Butoxycarbonylamino)propionic acid (Boc-Dap-OH) is a derivative of amino acids, mainly used as an intermediate in organic synthesis and pharmaceutical chemistry, and can be used in the synthesis of peptide drug molecules and bioactive molecules.

Preparation

The raw material was dissolved inabsolute ethanol (5 mL), and the reaction flask was immersed in a water bath at 25 C. To the alcoholicsolution, 10% palladium-carbon (22.9 mg) and 1,4-cyclohexadiene (10 equivalents with respect to4; 0.47 mL, 5.0 mmol) were added, and the mixture was allowed to react under magnetic stirringovernight. After filtration over a short pad of Celite 545, the solvent was evaporated under reducedpressure conditions, and the solid residue was partitioned in a 1:1 (v/v) H2O/EtOAc mixture (10 mL).The aqueous phase was separated, back extracted with EtOAc (3 10 mL), concentrated under reducedpressure conditions, and lyophilized.Finally, the target product Boc-Dap-OH is obtained.

Definition

Boc-Dap-OH is an amino acid molecule that is a zwitterion. Therefore, the addition of a base is required to prepare a nucleophilic amino acid. It is commonly acts as a nucleophile to attack the acyl carbon.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Boc-Dap-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Boc-Dap-OH Suppliers

Americas 1 Belgium 1 Canada 1 China 191 Europe 3 France 1 Germany 5 India 5 Japan 5 Switzerland 4 United Kingdom 5 United States 29 Global 251
Shanghai Xiannuo Biotechnology Co., Ltd.
Tel
021-50718719 13918719472
Fax
021-50718719
Country
China
ProdList
979
Advantage
58
Shenzhen DBU TECH Co. Ltd.
Tel
13528871800
Fax
QQ:2405094377
Email
dbutech@163.com
Country
China
ProdList
502
Advantage
58
Sichuan HongRi Pharma-Tech Co., Ltd
Tel
18123311397
Fax
0838-2822568
Email
2065506070@qq.com
Country
China
ProdList
2037
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
ChemFuture PharmaTech (Jiangsu) Ltd
Tel
5108538618
Fax
86 510 85386988-8017
Email
suger.wang@chemfuture.com
Country
China
ProdList
832
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12386
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Sichuan Guanghan Bio-Tech Co., Ltd
Tel
+86-28-86127071
Fax
+86-28-86127072
Email
info@sino-produce.com
Country
China
ProdList
406
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
19951945301
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19185
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Lavem Chine Pharm Company
Tel
28-86066080 18280039962
Fax
86-28-8527-5264
Email
sales@lavemc.com
Country
China
ProdList
214
Advantage
67
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4001
Advantage
55
Shanghai Shenyue Chemical Co., Ltd.
Tel
021-021-52212593 18049974220
Fax
+86 (21) 51062076
Email
3060526242@qq.com
Country
China
ProdList
984
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Suzhou Sibian Chemical Technology Co.,Ltd.
Tel
0512-65617459 18915409046
Fax
0512-65617459
Email
sales@sibian-chem.com
Country
China
ProdList
1922
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9478
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18021050169
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4674
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9893
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2045
Advantage
56
NINGBO INNO PHARMCHEM CO.,LTD.
Tel
86-574-27787657
Fax
86-574-27912196
Email
info@dearchem.com
Country
China
ProdList
4613
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Nanjing Derno Pharmaceutical Technology Co., Ltd.
Tel
025-86957866 13952093866
Fax
025-68661287
Email
sales@dernopharm.com
Country
China
ProdList
930
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
More
Less

View Lastest Price from Boc-Dap-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-L-Dap-OH 73259-81-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-24
Sichuan Jiaying Lai Technology Co.,LTD
Product
Boc-Dap-OH 73259-81-1
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-18
Sichuan Jiaying Lai Technology Co.,LTD
Product
Boc-Dap-OH 73259-81-1
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-18

73259-81-1, Boc-Dap-OHRelated Search:

Cbz-beta-Amino-L-alanine (S)-1-N-BOC-4-N-FMOC-PIPERAZINE-2-CARBOXYLIC ACID (S)-N-1-Boc-N-4-Cbz-2-piperazine carboxylic acid (S)-4-Boc-Piperazine-3-carboxylic acid Boc-Dap-OH (S)-1-N-Boc-piperazine-2-carboxylic acid methyl ester 2,3-Diaminopropionic acid L-2,3-Diaminopropionic acid BOC-DAP(DNP)-OH BOC-L-DPA(BOC)-OH BOC-DAP(FMOC)-OH BOC-AZA-L-LEUCINE BOC-ALBIZZIIN BOC-BETA-N-BENZYLAMINO-L-ALA BOC-DAP(DNP)-OSU BOC-DAP(ALOC)-OH DCHA BOC-DAP(BOC)-OH DCHA BOC-DAP(ALOC)-OH

  • N-Boc-beta-amino-L-alanine
  • (2S)-3-amino-2-{[(tert-butoxy)carbonyl]amino}propanoic acid
  • N-alpha-L-(Butoxycarbonyl)-2,3-diaMinopropionic aci
  • 3-Amino-N-(tert-butoxycarbonyl)-L-alanine 97%
  • 3-Amino-Boc-L-alanin
  • Boc-Dapa-OH
  • 3-AMINO-(TERT-BUTOXYCARBONYL)-L-ALANINE
  • Nα-Boc-L-2,3-diaminopropionic acid≥ 98% (HPLC)
  • L-ALANINE, 3-AMINO-N-[(1,1-DIMETHYLETHOXY)CARBONYL]-
  • BOC-L-DAP-OH
  • BOC-L-DAPA-OH
  • BOC-L-2,3-DIAMINOPROPIONIC ACID
  • BOC-L-ALPHA,BETA-DIAMINOPROPIONIC ACID
  • BOC-DPR-OH
  • BOC-DAP-OH
  • BOC-ALPHA,BETA-DIAMINOPROPIONIC ACID
  • (S)-3-AMINO-2-(TERT-BUTOXYCARBONYLAMINO)PROPANOIC ACID
  • T-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID
  • N-ALPHA-BOC-(S)-2,3-DIAMINOPROPIONIC ACID
  • NALPHA-BOC-L-BETA-AMINOALANINE
  • N-ALPHA-BOC-L-DIAMINOPROPIONIC ACID
  • N-ALPHA-BOC-L-2,3-DIAMINOPROPIONIC ACID
  • N-ALPHA-BOC-BETA-AMINO-L-ALANINE
  • Boc-Dap-OH(Na-Boc-2,3-DiaMinopropionic acid)
  • 3-[(tert-butoxy)(carbaMoyl)aMino]propanoic acid
  • Nalpha-BOC-beta-AMino-L-alanine, 97% 1GR
  • Nalpha-Boc-2,3-diaminopropionic Acid 3-Amino-N-(tert-butoxycarbonyl)-L-alanine 3-Amino-N-Boc-L-alanine Boc-Dap-OH Boc-Dpr-OH
  • (<i>S</i>)-3-AMino-2-Boc-propionic acid
  • N2-tertbutoxycarbonyl-L-2,3-diaMinopropanoic acid
  • (S)-3-AMino-2-Boc-propionic acid
  • 3-Amino-N-(tert-butoxycarbonyl)-L-alanine
  • (S)-2-(AMinoMethyl)-4-(tert-butoxy)-4-oxobutanoic acid
  • (S)-2-[(tert-Butoxycarbonyl)amino]-3-aminopropionic acid
  • N2-(tert-Butoxycarbonyl)-(S)-2,3-diaminopropionic acid
  • N2-tert-Butoxycarbonyl-L-2,3-diaminopropionic acid
  • Nα-BOC-(S)-β-aminoalanine
  • Nα-Boc-L-β-aminoalanine
  • (Tert-Butoxy)Carbonyl Dap-OH
  • (S)-3-AMino-Boc-Alanine
  • N-ALPHA-T-BUTOXYCARBONYL-L-ALPHA,BETA-DIAMINOPROPIONIC ACID
  • N-ALPHA-L-(BUTOXYCARBONYL)2,3-DIAMINOPROPIONIC ACID
  • N-ALPHA-TERT-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID
  • (N-BOC-BETA-AMINO)-ALA-OH
  • N-T-BOC-BETA-AMINO-L-ALANINE
  • Boc-Dpr-OH, N-Boc-L-2,3-diaminopropanoic acid
  • Na-Boc-L-2,3-diaminopropionic acid
  • N-t-BOC-?amino-L-alanine
  • N-BOC-L-2,3-DIAMINOPROPANOIC ACID
  • (n-boc-β-amino)-ala-oh
  • BOC-L-DAP-OH BOC-L-2,3- DIAMINOPROPIONIC ACID
  • N-ALPHA-T-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID
  • NALPHA-tert-Butoxycarbonyl-L-2,3-diaminopropionic acid
  • N-ALPHA-L-(BUTOXYCARBONYL)-2,3-DIAMINOPROPIONIC
  • N-TERT-BOC-BETA-AMINO-L-ALANINE
  • 3-Amino-Boc-L-alanine
  • N(ɑ)-Boc-L-2,3-diaminopropionic acid, 97%
  • 3-Amino-(tert-butoxycarbonyl)-L-alanine, Boc-Dap-OH, Boc-Dpr-OH, (S)-3-Amino-2-(tert-butoxycarbonylamino)propanoic acid, Nα-Boc-L-2,3-diaminopropionic acid
  • 3-Amino-(tert-butoxycarbonyl)-L-alanine, Boc-Dpr-OH, (S)-3-Amino-2-(tert-butoxycarbonylamino)propanoic acid, Nα-Boc-L-2,3-diaminopropionic acid