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6-QUINOXALINECARBOXYLIC ACID

Product Name
6-QUINOXALINECARBOXYLIC ACID
CAS No.
6925-00-4
Chemical Name
6-QUINOXALINECARBOXYLIC ACID
Synonyms
QUINOXALINE-6-CARBOXYLIC ACID;B3299;AKOS BBS-00000436;AKOS BBS-00001971;RARECHEM AM LA 0027;IFLAB-BB F1716-0520;TIMTEC-BB SBB000185;6-quinoxalinecarboxylate;CHINOXALIN-6-CARBONSAEURE;QUINOXALINE-6-CARBOXYLATE
CBNumber
CB9721236
Molecular Formula
C9H6N2O2
Formula Weight
174.16
MOL File
6925-00-4.mol
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6-QUINOXALINECARBOXYLIC ACID Property

Melting point:
224-229 °C (dec.)
Boiling point:
355.1±27.0 °C(Predicted)
Density 
1.421±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
3.22±0.30(Predicted)
color 
Light Brown to Dark Brown
InChI
InChI=1S/C9H6N2O2/c12-9(13)6-1-2-7-8(5-6)11-4-3-10-7/h1-5H,(H,12,13)
InChIKey
JGQDBVXRYDEWGM-UHFFFAOYSA-N
SMILES
N1C2C(=CC(C(O)=O)=CC=2)N=CC=1
CAS DataBase Reference
6925-00-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
703834
Product name
Quinoxaline-6-carboxylic acid
Purity
97%
Packaging
1g
Price
$26
Updated
2023/01/07
Sigma-Aldrich
Product number
703834
Product name
Quinoxaline-6-carboxylic acid
Purity
97%
Packaging
5g
Price
$93.4
Updated
2023/01/07
TRC
Product number
Q765260
Product name
6-QuinoxalinecarboxylicAcid
Packaging
25g
Price
$625
Updated
2021/12/16
TRC
Product number
Q765260
Product name
6-QuinoxalinecarboxylicAcid
Packaging
10g
Price
$325
Updated
2021/12/16
TRC
Product number
Q765260
Product name
6-QuinoxalinecarboxylicAcid
Packaging
5g
Price
$195
Updated
2021/12/16
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6-QUINOXALINECARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

Tan Solid

Uses

6-Quinoxalinecarboxylic Acid is an intermediate used in the production of antiprotozoal agents.

Synthesis

131543-46-9

619-05-6

6925-00-4

Stage 1: The compound (CAS:131543-46-9) was reacted with 3,4-diaminobenzoic acid in a mixed solvent of ethanol and acetic acid with glyoxal at 75 °C. After completion of the reaction, the resulting suspension was cooled to 5 °C and filtered. The collected wet cake of 6-quinoxaline carboxylic acid was washed with cold ethanol and subsequently dried under vacuum at 50 °C.

References

[1] Patent: US2007/179144, 2007, A1. Location in patent: Page/Page column 5; 6
[2] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 4, p. 815 - 820
[3] Patent: US2009/286797, 2009, A1. Location in patent: Page/Page column 6
[4] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 14, p. 3771 - 3774
[5] European Journal of Medicinal Chemistry, 2012, vol. 48, p. 255 - 264

6-QUINOXALINECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Glyoxal Ethanol Chloroform 3,4-Diaminobenzoic acid Ethyl acetate Acetic acid Methanol Sodium hydroxide Isopropyl alcohol Thionyl chloride

Preparation Products

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6-QUINOXALINECARBOXYLIC ACID Suppliers

Belgium 1 Canada 2 China 135 France 1 Germany 3 Hungary 1 India 5 South Korea 1 The Netherlands 1 Ukraine 2 United Kingdom 5 United States 26 Global 183
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
LIFE CHEMICALS, formerly I.F. Lab
Tel
--
Fax
--
Email
vasily.pinchuk@lifechemicals.com
Country
Canada
ProdList
6706
Advantage
69
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View Lastest Price from 6-QUINOXALINECARBOXYLIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Quinoxaline-6-carboxylic acid 6925-00-4
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Career Henan Chemical Co
Product
QUINOXALINE-6-CARBOXYLIC ACID 6925-00-4
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-21

6925-00-4, 6-QUINOXALINECARBOXYLIC ACIDRelated Search:

METHYL 6-QUINOXALINECARBOXYLATE 6-QUINOXALINECARBONITRILE Boronic acid, 6-quinoxalinyl- (9CI) QUINOXALINE-6-CARBALDEHYDE 6-Quinoxalinepropanoic acid, β-oxo-, ethyl ester 3-Quinolinecarboxylic acid 2,3-DIMETHYL-6-QUINOXALINECARBOXYLIC ACID 3-HYDROXY-2-QUINOXALINECARBOXYLIC ACID 98%,3-HYDROXY-2-QUINOXALINECARBOXYLIC ACID 3-Oxo-4H-quinoxaline-2-carboxylic acid,2-Quinoxalinecarboxylic acid, 3,4-dihydro-3-oxo- 2-Quinoxalinecarboxylic acid ethyl ester 6-Quinoxalinecarboxylic acid, 2,3-dihydro- 2-QUINOXALINECARBOXYLIC ACID,2-QUINOXALINECARBOXYLIC ACID (KG LEVEL) 2-Quinoxalinecarboxylic acid, 6,7-dihydroxy- (9CI) 6-Chloro-2-quinoxalinecarboxylic acid 2-Quinoxalinecarboxylic acid methyl ester 6-Chloro-2-quinoxalinecarboxylic acid 1,4-dioxide 6,7-Dimethyl-3,4-dihydro-3-oxy-2-quinoxalinecarboxylic acid ethyl ester 2,3-DIETHYL-QUINOXALINE-6-CARBOXYLIC ACID

  • 6-QUINOXALINECARBOXYLIC ACID
  • IFLAB-BB F1716-0520
  • RARECHEM AM LA 0027
  • QUINOXALINE-6-CARBOXYLIC ACID
  • TIMTEC-BB SBB000185
  • CHINOXALIN-6-CARBONSAEURE
  • 6-Quinoxalinecarboxylic acid, 95+%
  • AKOS BBS-00001971
  • AKOS BBS-00000436
  • 6-Quinoxalinecarboxylic acid ,97%
  • B3299
  • 6-Carboxyquinoxaline, 6-Carboxy-1,4-benzodiazine
  • QUINOXALINE-6-CARBOXYLIC ACID-2
  • Quinoxaline-6-carboxylic acid 97%
  • 6-quinoxalinecarboxylate
  • QUINOXALINE-6-CARBOXYLATE
  • 6925-00-4
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Quinoxalines
  • Aromatics
  • Heterocycles
  • Intermediates
  • Carboxylic Acids
  • Quinolines, Isoquinolines & Quinoxalines
  • Carboxylic Acids
  • Quinolines, Isoquinolines & Quinoxalines