ChemicalBook > CAS DataBase List > 2-FLUORO-5-NITROPHENYLACETIC ACID

2-FLUORO-5-NITROPHENYLACETIC ACID

Product Name
2-FLUORO-5-NITROPHENYLACETIC ACID
CAS No.
195609-18-8
Chemical Name
2-FLUORO-5-NITROPHENYLACETIC ACID
Synonyms
2-FLUORO-5-NITROPHENYLACETIC;2-fluoro-5-nitrophenyl acetate;2-FLUORO-5-NITROPHENYLACETIC ACID;2-(2-fluoro-5-nitrophenyl)aceticaci;Benzeneacetic acid, 2-fluoro-5-nitro-;2-(2-Fluoro-5-nitrophenyl)acetic acid;3-(Carboxymethyl)-4-fluoronitrobenzene;2-FLUORO-5-NITROPHENYLACETIC ACID ISO 9001：2015 REACH
CBNumber
CB9730131
Molecular Formula
C8H6FNO4
Formula Weight
199.14
MOL File
195609-18-8.mol
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2-FLUORO-5-NITROPHENYLACETIC ACID Property

Melting point:
149-150
Boiling point:
375.5±27.0 °C(Predicted)
Density 
1.498
storage temp. 
Store at room temperature
form 
powder
pka
3.76±0.10(Predicted)
color 
Off white to faint lemon
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
F622040
Product name
2-Fluoro-5-nitrophenylaceticAcid
Packaging
5g
Price
$60
Updated
2021/12/16
AK Scientific
Product number
W4168
Product name
2-Fluoro-5-nitrophenylaceticacid
Packaging
1g
Price
$63
Updated
2021/12/16
Apolloscientific
Product number
PC7840
Product name
2-Fluoro-5-nitrophenylaceticacid
Packaging
25g
Price
$67
Updated
2021/12/16
SynQuest Laboratories
Product number
4754-3-01
Product name
2-Fluoro-5-nitrophenylacetic acid
Purity
98%
Packaging
25g
Price
$74
Updated
2021/12/16
Matrix Scientific
Product number
024824
Product name
2-Fluoro-5-nitrophenylacetic acid
Purity
98%
Packaging
25g
Price
$75
Updated
2021/12/16
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2-FLUORO-5-NITROPHENYLACETIC ACID Chemical Properties,Usage,Production

Chemical Properties

Light yellow crystalline

Uses

2-Fluoro-5-nitrophenylacetic acid can be used to prepare thickened heterocyclic compounds as protein kinase inhibitors.

Synthesis

451-82-1

195609-18-8

General procedure for the synthesis of 2-fluoro-5-nitrophenylacetic acid from o-fluorophenylacetic acid: o-fluorobenzoic acid (30.0 g, 0.19 mol) was dissolved in a mixed solution of concentrated sulfuric acid (50 mL) and water (10 mL). A mixed solution of fuming nitric acid (10 mL) and water (10 mL) was added slowly and dropwise at 0 °C. The reaction mixture was kept stirred at 0 °C for 30 min. Upon completion of the reaction, the resulting precipitate was collected by filtration and washed with cold water. Finally, the product was dried under vacuum to afford 2-(2-fluoro-5-nitrophenyl)acetic acid as a white solid (35.2 g, 91% yield).

References

[1] Patent: WO2010/91310, 2010, A1. Location in patent: Page/Page column 99
[2] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 15, p. 2229 - 2235
[3] Tetrahedron, 2000, vol. 56, # 50, p. 9809 - 9818
[4] Patent: US2006/30609, 2006, A1. Location in patent: Page/Page column 15

2-FLUORO-5-NITROPHENYLACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-FLUORO-5-NITROPHENYLACETIC ACID Suppliers

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View Lastest Price from 2-FLUORO-5-NITROPHENYLACETIC ACID manufacturers

Qingdao RENAS Polymer Material Co., Ltd.
Product
2-(cyclopentyloxy)benzoic acid 195609-18-8
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2025-05-12
Qingdao RENAS Polymer Material Co., Ltd.
Product
2-(2-fluoro-5-nitrophenyl)acetic acid 195609-18-8
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2025-05-12
Henan Fengda Chemical Co., Ltd
Product
2-FLUORO-5-NITROPHENYLACETIC ACID 195609-18-8
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-26

195609-18-8, 2-FLUORO-5-NITROPHENYLACETIC ACIDRelated Search:


  • 2-FLUORO-5-NITROPHENYLACETIC ACID
  • 3-(Carboxymethyl)-4-fluoronitrobenzene
  • 2-fluoro-5-nitrophenyl acetate
  • 2-FLUORO-5-NITROPHENYLACETIC
  • 2-(2-Fluoro-5-nitrophenyl)acetic acid
  • Benzeneacetic acid, 2-fluoro-5-nitro-
  • 2-(2-fluoro-5-nitrophenyl)aceticaci
  • 2-FLUORO-5-NITROPHENYLACETIC ACID ISO 9001：2015 REACH
  • 195609-18-8
  • Phenylacetic acid