2-Methylglutaric Acid Property

Melting point:

80-82 °C(lit.)

Boiling point:

214-215 °C22 mm Hg(lit.)

Density 

1.246

vapor pressure 

0.001Pa at 20℃

Flash point:

149℃

storage temp. 

Store below +30°C.

solubility 

DMF: 20 mg/ml; DMSO: 16 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 10 mg/ml

form 

powder to crystal

pka

4.57±0.10(Predicted)

color 

White to Light yellow

PH

2.8 (10g/L in H2O)

Water Solubility 

Soluble in water.

InChI

InChI=1S/C6H10O4/c1-4(6(9)10)2-3-5(7)8/h4H,2-3H2,1H3,(H,7,8)(H,9,10)

InChIKey

AQYCMVICBNBXNA-UHFFFAOYSA-N

SMILES

C(O)(=O)C(C)CCC(O)=O

LogP

-1.3 at 20℃

EPA Substance Registry System

2-Methylglutaric acid (617-62-9)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2917198090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-Methylglutaric Acid Chemical Properties,Usage,Production

Description

(2)-Methylglutaric acid is a metabolite found in or produced by Saccharomyces cerevisiae. It is used in of sparsely pillared organic-inorganic hybrid compound.

Uses

2-Methylglutaric acid is used as primary and secondary intermediates in pharmaceutical and chemical research.

Definition

ChEBI: 2-methylglutaric acid is an alpha,omega-dicarboxylic acid that is glutaric acid substituted at position 2 by a methyl group. It has a role as a mammalian metabolite. It is an alpha,omega-dicarboxylic acid and a dicarboxylic fatty acid. It is functionally related to a glutaric acid. It is a conjugate acid of a 2-methylglutarate(2-).

Flammability and Explosibility

Non flammable

References

1. Effects of Relative Humidity and Particle Phase Water on the Heterogeneous OH Oxidation of 2-Methylglutaric Acid Aqueous Droplets. DOI:10.1021/acs.jpca.6b11606
2. Synthesis of 2‐Methylglutaric Acid by Oxidation of 3‐Methyl‐1,2‐ cyclopentanedione on Anodically Generated Ce(IV). DOI:10.1002/chin.199538117