C6-NBD SPHINGOSINE, BETA-D-GLUCOSYL
- Product Name
- C6-NBD SPHINGOSINE, BETA-D-GLUCOSYL
- CAS No.
- 94885-03-7
- Chemical Name
- C6-NBD SPHINGOSINE, BETA-D-GLUCOSYL
- Synonyms
- HEXANOYL-NBD-GLUCOSYLCERAMIDE;C6?NBD-Sphingosine,?beta-D-lactosyl;C6-NBD SPHINGOSINE, BETA-D-GLUCOSYL;C6 NBD Glucosylceramide (d18:1/6:0);C6-NBD-GLUCOSYLCERAMIDE, FLUORESCENT;N-C6-NBD-BETA-D-GLUCOSYL-SPHINGOSINE;N-HEXANOYL-NBD-BETA-D-GLUCOSYL-SPHINGOSINE;N-(NBD-Aminocaproyl)sphingosine β-D-glucosyl;C6 NBD-Sphingosine, beta-D-glucosylsphingosine;N-(NBD-AMINOCAPROYL)SPHINGOSINE BETA-D-GLUCOSYL
- CBNumber
- CB9745205
- Molecular Formula
- C36H59N5O11
- Formula Weight
- 737.88
- MOL File
- Mol file
C6-NBD SPHINGOSINE, BETA-D-GLUCOSYL Property
- Density
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Chloroform:Methanol (5:1): Soluble; Methanol: Soluble
- form
- A solid
- pka
- 12.92±0.70(Predicted)
- color
- Yellow to orange
- Appearance
- Solid Powder
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 23209
- Product name
- C6 NBD Glucosylceramide (d18:1/6:0)
- Purity
- ≥98%
- Packaging
- 100μg
- Price
- $305
- Updated
- 2024/03/01
- Product number
- 23209
- Product name
- C6 NBD Glucosylceramide (d18:1/6:0)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $486
- Updated
- 2024/03/01
C6-NBD SPHINGOSINE, BETA-D-GLUCOSYL Chemical Properties,Usage,Production
Description
C6 NBD glucosylceramide (d18:1/6:0) is a biologically active derivative of glucosylceramide that is tagged with a fluorescent C-6 nitrobenzoxadiazole (C-6 NBD; ) group. C6 NBD glucosylceramide (d18:1/6:0) has been used to study the metabolism and internalization of glucosylceramide. [Matreya, LLC. Catalog No. 1622]
Uses
C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity[1][2][3].
References
[1] Kok JW, et al. Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9896-900. DOI:10.1073/pnas.86.24.9896
[2] Hayashi Y, et al. A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates. Anal Biochem. 2005 Oct 15;345(2):181-6. DOI:10.1016/j.ab.2005.05.029
[3] di Bartolomeo S, et al. Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells. Biochem Biophys Res Commun. 2001 Oct 19;288(1):269-74. DOI:10.1006/bbrc.2001.5748
C6-NBD SPHINGOSINE, BETA-D-GLUCOSYL Preparation Products And Raw materials
Raw materials
Preparation Products
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