1,6-BISMALEIMIDOHEXANE

Product Name: 1,6-BISMALEIMIDOHEXANE
CAS No.: 4856-87-5
Chemical Name: 1,6-BISMALEIMIDOHEXANE
Synonyms: BMH;Hmdm;GMBMI;NSC 12818;HEXYLDIMALEIMIDE;BIS-MALEIMIDOHEXANE;1,6-MaleiMidohexane;1,6-BMH crosslinker;1,6-dimaleimidohexane;1,6-HEXANE DIMALEIMIDE
CBNumber: CB9745265
Molecular Formula: C14H16N2O4
Formula Weight: 276.29
MOL File: 4856-87-5.mol

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1,6-BISMALEIMIDOHEXANE Property

Melting point:: 144 °C
Boiling point:: 419.2°C (rough estimate)
Density: 1.1933 (rough estimate)
refractive index: 1.5500 (estimate)
storage temp.: 0-6°C
solubility: Soluble in chloroform.
pka: -1.90±0.20(Predicted)
form: powder to crystal
color: White to Almost white
InChI: InChI=1S/C14H16N2O4/c17-11-5-6-12(18)15(11)9-3-1-2-4-10-16-13(19)7-8-14(16)20/h5-8H,1-4,9-10H2
InChIKey: PYVHLZLQVWXBDZ-UHFFFAOYSA-N
SMILES: C(N1C(=O)C=CC1=O)CCCCCN1C(=O)C=CC1=O
CAS DataBase Reference: 4856-87-5(CAS DataBase Reference)
EPA Substance Registry System: 1H-Pyrrole-2,5-dione, 1,1'-(1,6-hexanediyl)bis- (4856-87-5)

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Safety

RTECS: ON5520000
HS Code: 29251900
Toxicity: mouse,LD50,oral,215mg/kg (215mg/kg),Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 40(11), Pg. 109, 1975.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 936634
Product name: 1,6-BMH crosslinker
Purity: ≥95%
Packaging: 50MG
Price: $85
Updated: 2025/07/31

Sigma-Aldrich

Product number: S227145
Product name: 1,1'-(HEXANE-1,6-DIYL)BIS(1H-PYRROLE-2,5-DIONE)
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $113
Updated: 2025/07/31

Sigma-Aldrich

Product number: 936634
Product name: 1,6-BMH crosslinker
Purity: ≥95%
Packaging: 100MG
Price: $142
Updated: 2025/07/31

Sigma-Aldrich

Product number: S227145
Product name: 1,1'-(HEXANE-1,6-DIYL)BIS(1H-PYRROLE-2,5-DIONE)
Purity: AldrichCPR
Packaging: 5mg
Price: $110
Updated: 2024/03/01

TCI Chemical

Product number: B1787
Product name: 1,6-Bis(maleimido)hexane
Purity: >97.0%(HPLC)(N)
Packaging: 100mg
Price: $119
Updated: 2025/07/31

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1,6-BISMALEIMIDOHEXANE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A sulfhydryl reactive homobifunctional crosslinking reagent. Under mild conditions, will permit irreversible cross-linking of sulfhydral containing compounds at a pH range of 6.5 to 7.5. Spacer Arm: 16.1 Angstroms

Uses

A sulfhydryl reactive homobifunctional cross linking reagent. Under mild conditions, will permit irreversible cross-linking of sulfhydral containing compounds at a pH range of 6.5 to 7.5.

1,6-BISMALEIMIDOHEXANE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,6-BISMALEIMIDOHEXANE Suppliers

Americas 1 Canada 1 China 104 Europe 1 France 1 Germany 2 India 3 Japan 2 United Kingdom 6 United States 13 Global 134

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 023-13650506873 19923294409
Email: xingcanyaoye@sina.com
Country: China
ProdList: 1604
Advantage: 58

Changzhou Fourman Chemical Co., Ltd.

Tel: 0519-89882557 13912311481
Fax: 0519-8988-2559
Email: fourmanchem@163.com
Country: China
ProdList: 63
Advantage: 60

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-69209928 18796809688
Email: zhouyingxiang@highfine.com
Country: China
ProdList: 1356
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
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3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
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Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
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Country: China
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Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

4856-87-5, 1,6-BISMALEIMIDOHEXANERelated Search:

N-PROPYLMALEIMIDE N,N'-DIACETYL-1,6-DIAMINOHEXANE 1-HEXYL-PYRROLE-2,5-DIONE 6-(DIMETHYLAMINO)HEXYLAMINE N,N,N',N'-Tetramethyl-1,6-hexanediamine N-acetyl-1,6-diaminohexane N,N'-DIFORMYL-1,6-DIAMINOHEXANE N,N'-HEXAMETHYLENEBISACRYLAMIDE N,N'-DIETHYL-1,6-DIAMINOHEXANE 1,6-BISMALEIMIDOHEXANE N-N-BUTYLACRYLAMIDE N-Butylmaleimide

1,6-BISMALEIMIDOHEXANE

1,6-HEXANE DIMALEIMIDE

N,N'-HEXAMETHYLENEBISMALEIMIDE

N,N'-HEXAMETHYLENEDIMALEIMIDE

1,1'-(hexane-1,6-diyl)bis-1H-pyrrole-2,5-dione

1,6-Bis(maleimide)hexane

Hmdm

BIS-MALEIMIDOHEXANE

BMH

HEXYLDIMALEIMIDE

1,6-BISMALEIMIDOHEXANE 96+%

1,1'-Hexamethylenebis(3-pyrroline-2,5-dione)

N,N'-(1,6-Hexanediyl)bis(maleimide)

N,N'-(1,6-Hexanediyl)di(maleimide)

N,N'-(Hexane-1,6-diyl)dimaleimide

1-(6-maleimidohexyl)-3-pyrroline-2,5-quinone

1-[6-(2,5-dioxopyrrol-1-yl)hexyl]pyrrole-2,5-dione

1,6-MaleiMidohexane

GMBMI

NSC 12818

N,N'-Hexamethylenebismaleimide N,N'-Hexamethylenedimaleimide 1,6-Di(maleimido)hexane

1,1’-(1,6-hexanediyl)bis-1h-pyrrole-2,5-dione

1,1’-(1,6-hexanediyl)bis-1h-pyrrole-5-dione

1,6-dimaleimidohexane

n,n’-hexamethylenedi-maleimid

BMH (bismaleimidohexane)

1,6-Bis(maleimido)hexane &gt

1H-Pyrrole-2,5-dione, 1,1'-(1,6-hexanediyl)bis-

1,1'-(Hexane-1,6-diyl)bis(1H-pyrrole-2,5-dione)

1,6-BMH crosslinker

1,1'-(Hexan-1,6-diyl)bis(1H-pyrrol-2,5-dione)

4856-87-5

4856-78-5

N-Substituted Maleimides

N-Substituted Maleimides, Succinimides & Phthalimides

pharmacetical

Maleimide Derivatives

N-Substituted Maleimides

N-Substituted Maleimides, Succinimides & Phthalimides

Cross Linking Reagents

MTS & Sulfhydryl Active Reagents