ChemicalBook > CAS DataBase List > 1,6-BISMALEIMIDOHEXANE

1,6-BISMALEIMIDOHEXANE

Product Name
1,6-BISMALEIMIDOHEXANE
CAS No.
4856-87-5
Chemical Name
1,6-BISMALEIMIDOHEXANE
Synonyms
BMH;Hmdm;GMBMI;NSC 12818;HEXYLDIMALEIMIDE;BIS-MALEIMIDOHEXANE;1,6-MaleiMidohexane;1,6-BMH crosslinker;1,6-dimaleimidohexane;1,6-HEXANE DIMALEIMIDE
CBNumber
CB9745265
Molecular Formula
C14H16N2O4
Formula Weight
276.29
MOL File
4856-87-5.mol
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1,6-BISMALEIMIDOHEXANE Property

Melting point:
144 °C
Boiling point:
419.2°C (rough estimate)
Density 
1.1933 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
0-6°C
solubility 
Soluble in chloroform.
pka
-1.90±0.20(Predicted)
form 
powder to crystal
color 
White to Almost white
InChI
InChI=1S/C14H16N2O4/c17-11-5-6-12(18)15(11)9-3-1-2-4-10-16-13(19)7-8-14(16)20/h5-8H,1-4,9-10H2
InChIKey
PYVHLZLQVWXBDZ-UHFFFAOYSA-N
SMILES
C(N1C(=O)C=CC1=O)CCCCCN1C(=O)C=CC1=O
CAS DataBase Reference
4856-87-5(CAS DataBase Reference)
EPA Substance Registry System
1H-Pyrrole-2,5-dione, 1,1'-(1,6-hexanediyl)bis- (4856-87-5)
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Safety

RTECS 
ON5520000
HS Code 
29251900
Toxicity
mouse,LD50,oral,215mg/kg (215mg/kg),Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 40(11), Pg. 109, 1975.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
936634
Product name
1,6-BMH crosslinker
Purity
≥95%
Packaging
50MG
Price
$85
Updated
2025/07/31
Sigma-Aldrich
Product number
S227145
Product name
1,1'-(HEXANE-1,6-DIYL)BIS(1H-PYRROLE-2,5-DIONE)
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
936634
Product name
1,6-BMH crosslinker
Purity
≥95%
Packaging
100MG
Price
$142
Updated
2025/07/31
Sigma-Aldrich
Product number
S227145
Product name
1,1'-(HEXANE-1,6-DIYL)BIS(1H-PYRROLE-2,5-DIONE)
Purity
AldrichCPR
Packaging
5mg
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
B1787
Product name
1,6-Bis(maleimido)hexane
Purity
>97.0%(HPLC)(N)
Packaging
100mg
Price
$119
Updated
2025/07/31
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1,6-BISMALEIMIDOHEXANE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A sulfhydryl reactive homobifunctional crosslinking reagent. Under mild conditions, will permit irreversible cross-linking of sulfhydral containing compounds at a pH range of 6.5 to 7.5. Spacer Arm: 16.1 Angstroms

Uses

A sulfhydryl reactive homobifunctional cross linking reagent. Under mild conditions, will permit irreversible cross-linking of sulfhydral containing compounds at a pH range of 6.5 to 7.5.

1,6-BISMALEIMIDOHEXANE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,6-BISMALEIMIDOHEXANE Suppliers

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4856-87-5, 1,6-BISMALEIMIDOHEXANERelated Search:

N-PROPYLMALEIMIDE N,N'-DIACETYL-1,6-DIAMINOHEXANE 1-HEXYL-PYRROLE-2,5-DIONE 6-(DIMETHYLAMINO)HEXYLAMINE N,N,N',N'-Tetramethyl-1,6-hexanediamine N-acetyl-1,6-diaminohexane N,N'-DIFORMYL-1,6-DIAMINOHEXANE N,N'-HEXAMETHYLENEBISACRYLAMIDE N,N'-DIETHYL-1,6-DIAMINOHEXANE 1,6-BISMALEIMIDOHEXANE N-N-BUTYLACRYLAMIDE N-Butylmaleimide

  • 1,6-BISMALEIMIDOHEXANE
  • 1,6-HEXANE DIMALEIMIDE
  • N,N'-HEXAMETHYLENEBISMALEIMIDE
  • N,N'-HEXAMETHYLENEDIMALEIMIDE
  • 1,1'-(hexane-1,6-diyl)bis-1H-pyrrole-2,5-dione
  • 1,6-Bis(maleimide)hexane
  • Hmdm
  • BIS-MALEIMIDOHEXANE
  • BMH
  • HEXYLDIMALEIMIDE
  • 1,6-BISMALEIMIDOHEXANE 96+%
  • 1,1'-Hexamethylenebis(3-pyrroline-2,5-dione)
  • N,N'-(1,6-Hexanediyl)bis(maleimide)
  • N,N'-(1,6-Hexanediyl)di(maleimide)
  • N,N'-(Hexane-1,6-diyl)dimaleimide
  • 1-(6-maleimidohexyl)-3-pyrroline-2,5-quinone
  • 1-[6-(2,5-dioxopyrrol-1-yl)hexyl]pyrrole-2,5-dione
  • 1,6-MaleiMidohexane
  • GMBMI
  • NSC 12818
  • N,N'-Hexamethylenebismaleimide N,N'-Hexamethylenedimaleimide 1,6-Di(maleimido)hexane
  • 1,1’-(1,6-hexanediyl)bis-1h-pyrrole-2,5-dione
  • 1,1’-(1,6-hexanediyl)bis-1h-pyrrole-5-dione
  • 1,6-dimaleimidohexane
  • n,n’-hexamethylenedi-maleimid
  • BMH (bismaleimidohexane)
  • 1,6-Bis(maleimido)hexane &gt
  • 1H-Pyrrole-2,5-dione, 1,1'-(1,6-hexanediyl)bis-
  • 1,1'-(Hexane-1,6-diyl)bis(1H-pyrrole-2,5-dione)
  • 1,6-BMH crosslinker
  • 1,1'-(Hexan-1,6-diyl)bis(1H-pyrrol-2,5-dione)
  • 4856-87-5
  • 4856-78-5
  • N-Substituted Maleimides
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • pharmacetical
  • Maleimide Derivatives
  • N-Substituted Maleimides
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • Cross Linking Reagents
  • MTS & Sulfhydryl Active Reagents