ChemicalBook > CAS DataBase List > 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE

1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE

Product Name
1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE
CAS No.
2113-05-5
Chemical Name
1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE
Synonyms
BUTTPARK 45\01-23;M-CPBG HYDROCHLORIDE;m-Chlorophenylbiguanide HCl;1-(3-Chlorophenyl)biguanideHCl;M-CHLOROPHENYLBIGUANIDE HYDROCHLORIDE;1-(3-CHLOROPHENYL)BIGUANIDE, HYDROCHLOR&;1-（3-Chlorophenyl)biguanide hydrochlorid;1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE;1-(M-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE;1-(m-chlorophenyl)-biguanidmonohydrochloride
CBNumber
CB9760998
Molecular Formula
C8H11Cl2N5
Formula Weight
248.11
MOL File
2113-05-5.mol
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1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Property

Melting point:
190-194 °C(lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: soluble
form 
solid
color 
white
Water Solubility 
Soluble to 100 mM in water
Sensitive 
Hygroscopic
CAS DataBase Reference
2113-05-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
DU1780000
HS Code 
2925290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C144
Product name
1-(3-Chlorophenyl)biguanide hydrochloride
Purity
solid
Packaging
500mg
Price
$75.5
Updated
2023/01/07
Tocris
Product number
0440
Product name
m-Chlorophenylbiguanidehydrochloride
Purity
≥98%(HPLC)
Packaging
100
Price
$63
Updated
2021/12/16
TRC
Product number
C375230
Product name
1-(3-Chlorophenyl)biguanide hydrochloride
Packaging
25mg
Price
$85
Updated
2021/12/16
Usbiological
Product number
255743
Product name
m-Chlorophenylbiguanide hydrochloride
Packaging
100mg
Price
$290
Updated
2021/12/16
Apolloscientific
Product number
OR0928
Product name
1-(3-Chlorophenyl)biguanide hydrochloride
Packaging
5g
Price
$60
Updated
2021/12/16
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1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Specific agonist for 5-HT receptor

Biological Activity

Prototypical potent and selective 5-HT 3 receptor agonist.

in vivo

m-CPBG hydrochloride (80 and 160 nM) significantly reduces water intake elicited by an acute salt load[1].
m-CPBG hydrochloride (third ventricle injection; 160 nM) significantly inhibits water intake in hypovolemic animals[1].
m-CPBG hydrochloride (third ventricle injection; 320 nM) decreases water intake in water-deprived rats[1].
m-CPBG hydrochloride (central administration） inhibits water intake induced by pharmacological activation of central cholinergic and angiotensinergic pathways[1].

Animal Model:Wistar male rats[1]
Dosage:80, 160 and 320 nM
Administration:Ventricle injection
Result:Decreased water intake induced by water deprivation, acute salt load and hypovolemia.

storage

Desiccate at RT

1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Suppliers

China 52 France 1 Germany 3 India 2 Switzerland 1 The Netherlands 1 United Kingdom 12 United States 17 Global 89
Meryer (Shanghai) Chemical Technology Co., Ltd.
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3B Pharmachem (Wuhan) International Co.,Ltd.
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China
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Alfa Aesar
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021-67582001/03/05
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Energy Chemical
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Wuhan TCASChem Technology Co., Ltd.
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Shanghai potentpharm CO.,Ltd
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EMMX Biotechnology LLC
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Shanghai Send Pharmaceutical Technology Co., Ltd.
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Shanghai YuanYe Biotechnology Co., Ltd.
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2113-05-5, 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDERelated Search:

PROGUANIL HYDROCHLORIDE Biguanide Biguanide hydrochloride Chlorhexidine hydrochloride 1-(2-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE 1-(4-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Chlorhexidine Diacetate Chlorhexidine 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE 1-(3-CHLORO-4-FLUOROPHENYL)BIGUANIDE HYDROCHLORIDE 1-(3,5-DICHLOROPHENYL)BIGUANIDE HYDROCHLORIDE 1-(2,5-DICHLOROPHENYL)BIGUANIDE HYDROCHLORIDE 1-(2-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE 97%,1-(2-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE 1,5-Bis-(4-chlorophenyl)biguanide hydrochloride 1-(3,4-DICHLOROPHENYL)BIGUANIDE HYDROCHLORIDE 1-(3-CHLORO-2-FLUOROPHENYL)BIGUANIDE HYDROCHLORIDE 1-(2,3-DICHLOROPHENYL)BIGUANIDE HYDROCHLORIDE SALOR-INT L136492-1EA

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