ChemicalBook > CAS DataBase List > 20-CARBOXY-LEUKOTRIENE B4

20-CARBOXY-LEUKOTRIENE B4

Product Name
20-CARBOXY-LEUKOTRIENE B4
CAS No.
80434-82-8
Chemical Name
20-CARBOXY-LEUKOTRIENE B4
Synonyms
20-COOH-LTB4;20-CARBOXY-LEUKOTRIENE B4;20-hydroxy-20-oxoleukotriene B4;5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID;(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid;6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
CBNumber
CB9769067
Molecular Formula
C20H30O6
Formula Weight
366.45
MOL File
80434-82-8.mol
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20-CARBOXY-LEUKOTRIENE B4 Property

Boiling point:
588.3±50.0 °C(Predicted)
Density 
1.151±0.06 g/cm3(Predicted)
Flash point:
14℃
storage temp. 
−20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
form 
Liquid
pka
4.66±0.10(Predicted)
color 
Colorless to light yellow
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 1170 3/PG 2
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C6046
Product name
20-Carboxy-leukotriene B4
Purity
~1?mg/mL in ethanol, ≥90% (HPLC)
Packaging
25μg
Price
$428
Updated
2023/06/20
Cayman Chemical
Product number
20180
Product name
20-carboxy Leukotriene B4
Purity
≥97%
Packaging
25μg
Price
$174
Updated
2024/03/01
Cayman Chemical
Product number
20180
Product name
20-carboxy Leukotriene B4
Purity
≥97%
Packaging
50μg
Price
$328
Updated
2024/03/01
Cayman Chemical
Product number
20180
Product name
20-carboxy Leukotriene B4
Purity
≥97%
Packaging
100μg
Price
$618
Updated
2024/03/01
TRC
Product number
C724805
Product name
20-COOH-LTB4
Packaging
100μg
Price
$540
Updated
2021/12/16
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20-CARBOXY-LEUKOTRIENE B4 Chemical Properties,Usage,Production

Description

20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. The resulting 20-hydroxy LTB4 is further oxidized to 20-carboxy LTB4. LTB4 metabolism in isolated rat hepatocytes also results in production of 20-carboxy LTB4 along with other ω-oxidation products. The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degranulation.

Uses

20-COOH-LTB4 is a leukotriene B4 metabolite and substrate for β-oxidation pathways.

Definition

ChEBI: A member of the class of leukotrienes that is leukotriene B4 in which the terminal methyl group has undergone formal oxidation to the corresponding carboxylic acid.

20-CARBOXY-LEUKOTRIENE B4 Preparation Products And Raw materials

Raw materials

Preparation Products

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20-CARBOXY-LEUKOTRIENE B4 Suppliers

Shanghai EFE Biological Technology Co., Ltd.
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China
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80434-82-8, 20-CARBOXY-LEUKOTRIENE B4Related Search:


  • 20-CARBOXY-LEUKOTRIENE B4
  • 20-COOH-LTB4
  • 5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID
  • (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid
  • 20-hydroxy-20-oxoleukotriene B4
  • 6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
  • 80434-82-8
  • C20H30O6
  • Leukotrienes
  • Lipids
  • Fatty Acids
  • Biochemicals and Reagents
  • BioChemical
  • Fatty Acids
  • Leukotrienes
  • Lipids