ChemicalBook > CAS DataBase List > 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE

Product Name
2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE
CAS No.
149847-77-8
Chemical Name
2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE
Synonyms
2-MPMDQ;2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE;2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-6-methyl-2,6-dihydroimidazo[1,2-c]quinazolin-5(3H)-one;Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-
CBNumber
CB9771332
Molecular Formula
C23H27N5O2
Formula Weight
405.49
MOL File
Mol file
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2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Property

storage temp. 
Store at RT
solubility 
<20.27mg/ml in DMSO
form 
Powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
0661
Product name
2-MPMDQ
Packaging
10
Price
$154
Updated
2021/12/16
Tocris
Product number
0661
Product name
2-MPMDQ
Packaging
50
Price
$628
Updated
2021/12/16
TRC
Product number
M745853
Product name
2-MPMDQ
Packaging
2.5mg
Price
$195
Updated
2021/12/16
TRC
Product number
M745853
Product name
2-MPMDQ
Packaging
5mg
Price
$330
Updated
2021/12/16
Usbiological
Product number
254368
Product name
2-MPMDQ
Packaging
10mg
Price
$403
Updated
2021/12/16
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2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Chemical Properties,Usage,Production

Uses

2-MPMDQ is a novel class of α1-adrenoceptor antagonists and acts as an anti-hypertensive agent.

Definition

ChEBI: 2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5-one is a member of piperazines.

Biological Activity

Potent and selective α 1 -adrenoceptor antagonist; hypotensive.

References

[1]. chern jw, tao pl, yen mh, et al. studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. j med chem, 1993, 36(15): 2196-2207.

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Suppliers

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149847-77-8, 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONERelated Search:


  • 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE
  • 2-MPMDQ
  • Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-
  • 2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-6-methyl-2,6-dihydroimidazo[1,2-c]quinazolin-5(3H)-one
  • 149847-77-8