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DILEVALOL

Product Name
DILEVALOL
CAS No.
75659-07-3
Chemical Name
DILEVALOL
Synonyms
Levadil;Unicard;Dilevaol;Dilevalon;Sch-19927;DILEVALOL;Dilevalolum;DILEVALOL HCL;(R,R)-Labetalol;Dilevalolum [latin]
CBNumber
CB9773028
Molecular Formula
C19H24N2O3
Formula Weight
328.41
MOL File
75659-07-3.mol
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DILEVALOL Property

Boiling point:
552.7±50.0 °C(Predicted)
Density 
1.200±0.06 g/cm3(Predicted)
pka
8.21±0.31(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FL24822
Product name
Dilevalol
Packaging
10mg
Price
$145
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0019482
Product name
2-HYDROXY-5-((R)-1-HYDROXY-2-(((R)-4-PHENYLBUTAN-2-YL)AMINO)ETHYL)BENZAMIDE
Purity
95.00%
Packaging
5MG
Price
$498.88
Updated
2021/12/16
Biosynth Carbosynth
Product number
FL24822
Product name
Dilevalol
Packaging
50mg
Price
$507.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0019482
Product name
2-HYDROXY-5-((R)-1-HYDROXY-2-(((R)-4-PHENYLBUTAN-2-YL)AMINO)ETHYL)BENZAMIDE
Purity
95.00%
Packaging
1G
Price
$3104.85
Updated
2021/12/16
Crysdot
Product number
CD12036144
Product name
2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-4-phenylbutan-2-yl)amino)ethyl)benzamide
Purity
95+%
Packaging
1g
Price
$1583
Updated
2021/12/16
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DILEVALOL Chemical Properties,Usage,Production

Description

Dilevalol is a "dual-mechanism" antihypertensive reportedly suitable for a wide range of patients. Its partial beta2-agonist action is expected to induce vasodilation, whereas its beta1-antagonist component may protect against stress-induced hemodynamic charges without altering the cardiac output. Dilevalol is the R,R-isomer of labetalol.

Originator

Schering Plough (USA)

Uses

Specific competitive antagonist at both α-and β-adrenergic receptor sites. Antihypertensive.

Uses

(R,R)-Labetalol is a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol is used as an antihypertensive.

Definition

ChEBI: (R,R)-labetalol is a 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1R,2R-configuration. It is a conjugate base of a dilevalol(1+).

brand name

Levadil; Dilevalon

World Health Organization (WHO)

Dilevalol, a beta-adrenoreceptor antagonist, was introduced into medicine in 1989 for the treatment of hypertension. Shortly afterwards, its use became associated with isolated cases of hepatic toxicity. Although few cases were reported, the manufacturer discontinued sales in Japan and Portugal, the only countries where the drug was marketed, and withdrew applications for registration elsewhere.

DILEVALOL Preparation Products And Raw materials

Raw materials

Preparation Products

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DILEVALOL Suppliers

Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58

75659-07-3, DILEVALOLRelated Search:


  • 2-Hydroxy-5-[(R)-1-hydroxy-2-[[(R)-1-methyl-3-phenylpropyl]amino]ethyl]benzamide
  • Sch-19927
  • (-)-5-((1R)-1-Hydroxy-2-((1R)-1-methyl-3-phenylpropylamino)ethyl)salicylamid [iupac]
  • (R,R)-Labetalol
  • 2-Hydroxy-5-((1R)-1-hydroxy-2-(((1R)-1-methyl-3-phenylpropyl)amino)ethyl)benzamide
  • Benzamide, 2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-1-methyl-3-phenylpropyl)amino)ethyl)-
  • DILEVALOL
  • DILEVALOL HCL
  • Dilevaol
  • Dilevalon
  • Levadil
  • Unicard
  • 2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-4-phenylbutan-2-yl)aMino)ethyl)benzaMide
  • Benzamide, 2-hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)-, (R-(R*,R*))-
  • Dilevalolum
  • Dilevalolum [latin]
  • 75659-07-3
  • Amines
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals