4-IODOPHENYLACETONITRILE
- Product Name
- 4-IODOPHENYLACETONITRILE
- CAS No.
- 51628-12-7
- Chemical Name
- 4-IODOPHENYLACETONITRILE
- Synonyms
- 2-(4-iodophenyl)acetonitrile;p-IodobenzylCyanide;4-IODOBENZYL CYANIDE;4-IODOPHENYLACETONITRILE;4-Iodophenylacetonitrile 97%;4-Iodophenylacetonitrile-97%;Benzeneacetonitrile, 4-iodo-;2-(4-iodophenyl)ethanenitrile;4-Iodophenylacetonitrile 4-Iodobenzyl Cyanide p-Iodobenzyl Cyanide
- CBNumber
- CB9775608
- Molecular Formula
- C8H6IN
- Formula Weight
- 243.04
- MOL File
- 51628-12-7.mol
4-IODOPHENYLACETONITRILE Property
- Melting point:
- 53-57 °C(lit.)
- Boiling point:
- 152°C/ 3mm
- Density
- 1.764±0.06 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to crystal
- color
- White to Light yellow
- Water Solubility
- Insoluble in water
- Sensitive
- Light Sensitive
- BRN
- 1934479
- InChI
- 1S/C8H6IN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5H2
- InChIKey
- PNXWQTYSBFGIFD-UHFFFAOYSA-N
- SMILES
- Ic1ccc(CC#N)cc1
- CAS DataBase Reference
- 51628-12-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 587028
- Product name
- 4-Iodophenylacetonitrile
- Purity
- 97%
- Packaging
- 5g
- Price
- $48
- Updated
- 2025/07/31
- Product number
- 587028
- Product name
- 4-Iodophenylacetonitrile
- Purity
- 97%
- Packaging
- 1g
- Price
- $45.2
- Updated
- 2023/06/20
- Product number
- I1058
- Product name
- 4-Iodophenylacetonitrile
- Purity
- >95.0%(GC)
- Packaging
- 1g
- Price
- $35
- Updated
- 2025/07/31
- Product number
- I1058
- Product name
- 4-Iodophenylacetonitrile
- Purity
- >95.0%(GC)
- Packaging
- 5g
- Price
- $114
- Updated
- 2025/07/31
- Product number
- I718818
- Product name
- 2-(4-Iodophenyl)acetonitrile
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
4-IODOPHENYLACETONITRILE Chemical Properties,Usage,Production
Uses
4-Iodophenylacetonitrile is used as an intermediate in organic syntheses and in pharmaceuticals.
Synthesis
624-31-7
51628-12-7
The general procedure for the synthesis of 4-iodophenylacetonitrile using 4-iodotoluene as starting material was as follows: referring to the operation of Example 3, a mixture of 4.36 g (20.0 mmol) of p-iodotoluene (Tokyo Kasei), 3.92 g (22.0 mmol) of N-bromosuccinimide (Tokyo Kasei) and 60 mL of carbon tetrachloride (Wako Junyaku Kogyo) was refluxed under incandescent lamp for 4 h. 2.67 g (yield: 45.0%) of 4-iodobenzyl bromide was obtained and the product was a white crystal. Subsequently, 0.49 g (10.0 mmol) of sodium cyanide (Kokusan Kagaku) was dissolved in 10 mL of dimethyl sulfoxide (Aldrich) at 50 °C, 1.48 g (5.0 mmol) of the 4-iodobenzyl bromide prepared as described above was added, and the mixture was stirred for 3 h at room temperature. After the reaction was completed, the reaction mixture was dissolved in water, extracted with hexane, and the hexane was removed by evaporation to give 0.84 g (yield: 68.9%) of 4-iodobenzylacetonitrile, the product was white crystal.
References
[1] Patent: US5574062, 1996, A
[2] Patent: US5574062, 1996, A
[3] Journal of Organic Chemistry, 2017, vol. 82, # 2, p. 1114 - 1126
4-IODOPHENYLACETONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-IODOPHENYLACETONITRILE manufacturers
- Product
- 4-IODOPHENYLACETONITRILE 51628-12-7
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- JD724
- Release date
- 2019-09-02