ChemicalBook > CAS DataBase List > 2-HYDRAZINOBENZOTHIAZOLE

2-HYDRAZINOBENZOTHIAZOLE

Product Name: 2-HYDRAZINOBENZOTHIAZOLE
CAS No.: 615-21-4
Chemical Name: 2-HYDRAZINOBENZOTHIAZOLE
Synonyms: 2 HzBTZ;2-HzBTZ;IDO1-IN-1;AKOS B003351;AKOS BC-3071;IDO1 inhibitor 1;IDO1-inhibitor-1;AKOS BBS-00007373;IFLAB-BB F0896-0067;SALOR-INT L482064-1EA
CBNumber: CB9782736
Molecular Formula: C7H7N3S
Formula Weight: 165.22
MOL File: 615-21-4.mol

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2-HYDRAZINOBENZOTHIAZOLE Property

Melting point:: 198-202 °C (lit.)
Boiling point:: 352.4±25.0 °C(Predicted)
Density: 1.2404 (rough estimate)
refractive index: 1.5500 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: Solubility in hot methanol almost transparent.
pka: 2.81±0.20(Predicted)
form: powder to crystal
color: White to Light yellow to Light orange
InChI: InChI=1S/C7H7N3S/c8-10-7-9-5-3-1-2-4-6(5)11-7/h1-4H,8H2,(H,9,10)
InChIKey: JYSUYJCLUODSLN-UHFFFAOYSA-N
SMILES: S1C2=CC=CC=C2N=C1NN
CAS DataBase Reference: 615-21-4(CAS DataBase Reference)
EPA Substance Registry System: 2(3H)-Benzothiazolone, hydrazone (615-21-4)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/38
Safety Statements: 26-36
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: DL4725000
TSCA: Yes
HazardClass: IRRITANT
PackingGroup: III
HS Code: 29342000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 642436
Product name: 2-Hydrazinobenzothiazole
Purity: 97%
Packaging: 5g
Price: $77.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: 642436
Product name: 2-Hydrazinobenzothiazole
Purity: 97%
Packaging: 25g
Price: $298
Updated: 2023/06/20

TCI Chemical

Product number: H0177
Product name: 2-Hydrazinobenzothiazole
Purity: >99.0%(T)
Packaging: 5g
Price: $53
Updated: 2025/07/31

TCI Chemical

Product number: H0177
Product name: 2-Hydrazinobenzothiazole
Purity: >99.0%(T)
Packaging: 25g
Price: $142
Updated: 2025/07/31

TRC

Product number: H999798
Product name: 2-Hydrazinylbenzo[d]thiazole
Packaging: 10mg
Price: $45
Updated: 2021/12/16

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2-HYDRAZINOBENZOTHIAZOLE Chemical Properties,Usage,Production

Chemical Properties

slightly yellow to beige-green crystalline powder

Uses

It is employed in the spectrophotometric analysis determination of methenamine and its salts. It is also used in the detection and repair mechanism of Etheno-DNA adducts.

Synthesis

136-95-8

615-21-4

General procedure for the synthesis of 2-hydrazinobenzothiazole from 2-aminobenzothiazole: Hydrazine hydrate (1 equiv.) was dissolved in ethylene glycol at 5 °C. Under stirring, concentrated hydrochloric acid (2 mL) was added slowly and dropwise, followed by 2-aminobenzothiazole (1 eq.). The reaction mixture was heated to reflux for 2-3 hours, after which it was cooled to room temperature. Upon completion of the reaction, the solid product formed was collected by filtration, washed with water and purified by recrystallization from ethanol to afford the target compound 2-hydrazinobenzo[d]thiazole (32). The product was white crystals in 90% yield with a melting point ranging from 200 °C to 202 °C. 1H NMR (DMSO-d6, 400 MHz) data were as follows: δ 4.84 (2H, s), 6.85-7.65 (4H, m), 8.62 (1H, s). ESI-MS (m/z) analysis showed the molecular ion peak as 166 (MH+).

References

[1] Helvetica Chimica Acta, 1980, vol. 63, # 3, p. 682 - 692
[2] European Journal of Medicinal Chemistry, 2015, vol. 103, p. 418 - 428
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 14, p. 4022 - 4025
[4] Medicinal Chemistry Research, 2012, vol. 21, # 9, p. 2428 - 2442
[5] Journal of Molecular Structure, 2014, vol. 1060, # 1, p. 215 - 222

2-HYDRAZINOBENZOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDRAZINOBENZOTHIAZOLE Suppliers

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View Lastest Price from 2-HYDRAZINOBENZOTHIAZOLE manufacturers

Dideu Industries Group Limited

Product: 2-HYDRAZINOBENZOTHIAZOLE 615-21-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2025-09-30

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-Hydrazinobenzothiazole 615-21-4
Price: US $1.10-9.90/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 100KG
Release date: 2025-08-20

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Hydrazinobenzothiazole 615-21-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

615-21-4, 2-HYDRAZINOBENZOTHIAZOLERelated Search:

1-(6-CHLORO-1,3-BENZOTHIAZOL-2-YL)HYDRAZINE 2-HYDRAZINOBENZOTHIAZOLE ACETONE-BENZOTHIAZOLYL-2-HYDRAZONE 4-Methyl-2-benzothiazolehydrazine 6-BROMO-2-HYDRAZINO-1,3-BENZOTHIAZOLE HYDRAZINE (6-NITROBENZOTHIAZOL-2-YL)-HYDRAZINE 3-[1-(1,3-benzothiazol-2-yl)hydrazino]propanenitrile ETHYL 4-AZA-4-(BENZOTHIAZOL-2-YLAMINO)-3-(TRIFLUOROMETHYL)BUT-3-ENOATE AURORA 12505 BUTTPARK 137\40-05 PRINCETON PBMR000200 5-CHLORO-2-HYDRAZINO-1,3-BENZOTHIAZOLE 3-(AZA(BENZOTHIAZOL-2-YLAMINO)METHYLENE)INDOLIN-2-ONE BUTTPARK 137\40-03 BUTTPARK 137\40-57 3-{5-[(E)-(1,3-BENZOTHIAZOL-2-YLHYDRAZONO)METHYL]-2-FURYL}BENZOIC ACID AURORA 2430

2-HYDRAZINOBENZOTHIAZOLE, 99% (TITR.)

(Benzothiazole-2-yl)hydrazine

1-(2-Benzothiazolyl)hydrazine

1-(Benzothiazol-2-yl)hydrazine

2-Hydrazinobenzothiazole,99%

2-benzothiazolinone,hydrazone

Benzothiazolohydrazine

2-hydrazinyl-Benzothiazole

2-hydrazino-1,3-benzothiazole(SALTDATA: FREE)

2-Hydrazinylbenzo[d]thiazole

1,3-benzothiazol-2-ylhydrazine

2-Benzothiazolinone, hydrazone (7CI)

JR-8574, 1-(Benzo[d]thiazol-2-yl)hydrazine, 97%

2-hydrazino-benzothiazol

SALOR-INT L482064-1EA

BENZOTHIAZOL-2-YL-HYDRAZINE

IFLAB-BB F0896-0067

AKOS B003351

AKOS BC-3071

AKOS BBS-00007373

1-(BENZO[D]THIAZOL-2-YL)HYDRAZINE

2 (3H)-BENZOTHIAZOLONE HYDRAZONE

2-BENZOTHIAZOLEHYDRAZONE

2-BENZOTHIAZOLYLHYDRAZINE

2-HYDRAZINOBENZOTHIAZOLE

2-HYDRAZINO-1,3-BENZOTHIAZOLE

Benzothiazole, 2-hydrazino.

2-Hydrazino-1,3-benzothiazole 97%

2(3H)-Benzothiazolone,hydrazone(9CI)

2-Hydrazinobenzothiazole&gt

Benzothiazole, 2-hydrazinyl-

IDO1-IN-1

2 HzBTZ

2-HzBTZ

IDO1 inhibitor 1

IDO1-inhibitor-1

2- hydrazide benzothiazole

IDO1-IN-1, 10 mM in DMSO

615-21-4

Heterocyclic Building Blocks

Thiazoles

Building Blocks

Thiazoles, Isothiazoles &Benzothiazoles

Heterocyclic Compounds

Thiazole

Thiazoles, Isothiazoles & Benzothiazoles

BENZOTHIAZOLE