MBP (85-99) peptide antagonist trifluoroacetate salt

Product Name: MBP (85-99) peptide antagonist trifluoroacetate salt
CAS No.: 444305-16-2
Chemical Name: MBP (85-99) peptide antagonist trifluoroacetate salt
Synonyms: MBP 85-99;J5 peptide;MBP (85-99);EKPKVEAYKAAAAPA;MBP (85-99) peptide antagonist;93:PN:US7456252 SEQID:93 claimed sequence;Myelin Basic Protein (85-99) Peptide Antagonist;Myelin Basic Protein (85-99) Peptide Antagonist tr;MBP (85-99) peptide antagonist trifluoroacetate salt;H-GLU-LYS-PRO-LYS-VAL-GLU-ALA-TYR-LYS-ALA-ALA-ALA-ALA-PRO-ALA-OH
CBNumber: CB9787438
Molecular Formula: C70H114N18O21
Formula Weight: 1543.78
MOL File: 444305-16-2.mol

More

Less

MBP (85-99) peptide antagonist trifluoroacetate salt Property

Boiling point:: 1860.2±65.0 °C(Predicted)
Density: 1.299±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: H2O: >1mg/mL
form: lyophilized powder
pka: 3.70±0.10(Predicted)
Sequence: Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala-Ala-Ala-Ala-Pro-Ala

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M0571
Product name: MBP (85-99) peptide antagonist trifluoroacetate salt
Purity: 95% (HPLC), lyophilized powder
Packaging: 1mg
Price: $319
Updated: 2022/05/15

American Custom Chemicals Corporation

Product number: PRO0001659
Product name: H-GLU-LYS-PRO-LYS-VAL-GLU-ALA-TYR-LYS-ALA-ALA-ALA-ALA-PRO-ALA-OH
Purity: 95.00%
Packaging: 5MG
Price: $501.97
Updated: 2021/12/16

More

Less

MBP (85-99) peptide antagonist trifluoroacetate salt Chemical Properties,Usage,Production

Description

MBP (85-99) peptide antagonist, or J5, is a 15 amino acid peptide fragment designed on the binding motif of MBP 85-99 (myelin basic protein 85-99) to HLA-DR2 (human leukocyte antigen-DR2), which competes with and inhibits the binding of MBP (85-99) to HLA-DR2 and IL-2. MBP 85-99 is the the immunodominant epitope of MBP and a major candidate autoantigen in multiple sclerosis (MS), making this peptide a useful tool for MS research. p>

Biochem/physiol Actions

MBP (85-99) peptide antagonist inhibits binding of MBP 85-99 to HLA-DR2 and IL-2; tool for MS research. MBP (85-99) peptide antagonist inhibits the binding of MBP 85-99 to HLA-DR2 and IL-2 and is a tool for MS research. The peptide antagonist is a 15-mer peptide that competes with Myelin Basic Protein MBP (85-99), the immunodominant epitope of MBP and major candidate autoantigen in multiple sclerosis (MS).

References

[1] CASSANDRA E SMITH. Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2005: 9595-9600. DOI:10.1073/pnas.0504131102.
[2] JOEL N H STERN. Peptide 15-mers of defined sequence that substitute for random amino acid copolymers in amelioration of experimental autoimmune encephalomyelitis.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2005, 102 5: 1620-1625. DOI:10.1073/pnas.0409022102.
[3] FRIDKIS-HARELI M. Design of peptide immunotherapies for MHC Class-II-associated autoimmune disorders.[J]. Clinical & Developmental Immunology, 2013, 2013: 826191. DOI:10.1155/2013/826191.

MBP (85-99) peptide antagonist trifluoroacetate salt Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

MBP (85-99) peptide antagonist trifluoroacetate salt Suppliers

China 40 Switzerland 1 United States 1 Global 42

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5167
Advantage: 58

More

Less

View Lastest Price from MBP (85-99) peptide antagonist trifluoroacetate salt manufacturers

Dingwang Technology (Wuhan) Co., Ltd.

Product: MBP (85-99) peptide antagonist 444305-16-2
Price: US $0.00/gram
Min. Order: 1gram
Purity: 99% min
Supply Ability: 20 tons
Release date: 2024-05-21

444305-16-2, MBP (85-99) peptide antagonist trifluoroacetate saltRelated Search:

MBP (85-99) peptide antagonist trifluoroacetate salt ALA-ALA-ALA (Ser(POH)3·)-Tau Peptide (379-408) Myelin Oligodendrocyte Glycoprotein Peptide (79-96) rat GnRH Associated Peptide (GAP) (1-24), human CDK2/CYCLIN INHIBITORY PEPTIDE I SPERM PEPTIDE P10G Prolactin-Releasing Peptide (1-31) (human) H-LEU-PRO-GLY-LEU-PRO-SER-ALA-ALA-SER-SER-GLU-ASP-ALA-GLY-GLN-SER-NH2 Tau Peptide (255-314) (Repeat 2 Domain)

MBP (85-99) peptide antagonist trifluoroacetate salt

H-GLU-LYS-PRO-LYS-VAL-GLU-ALA-TYR-LYS-ALA-ALA-ALA-ALA-PRO-ALA-OH

(4S)-4-amino-5-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxyethyl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-5-oxopentanoic acid

MBP (85-99) peptide antagonist

Myelin Basic Protein (85-99) Peptide Antagonist

93:PN:US7456252 SEQID:93 claimed sequence

L-Alanine, L-α-glutamyl-L-lysyl-L-prolyl-L-lysyl-L-valyl-L-α-glutamyl-L-alanyl-L-tyrosyl-L-lysyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-prolyl-

MBP 85-99

MBP (85-99)

EKPKVEAYKAAAAPA

Myelin Basic Protein (85-99) Peptide Antagonist tr

J5 peptide

444305-16-2

C70H114N18O21

Neurobiology

Neuroscience

Neural Proteins