ChemicalBook > CAS DataBase List > SR 142948
SR 142948
- Product Name
- SR 142948
- CAS No.
- 184162-64-9
- Chemical Name
- SR 142948
- Synonyms
- SR 142948;LWULHXVBLMWCHO-UHFFFAOYSA-N;inhibit,HT 29,Neurotensin Receptor,SR 142948,CHO cells,SR142948,SR-142948,dopamine,neurotensin,Inhibitor,psychotic disorders;2-[(5-(2,6-DIMETHOXY-PHENYL)-1-(4-[(3-DIMETHYLAMINO-PROPYL)-METHYL-CARBAMOYL]-2-ISOPROPYL-PHENYL)-1H-PYRAZOLE-3-CARBONYL)-AMINO]-ADAMANTANE-2-CARBOXYLIC ACID;2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID;2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID;TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID, 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-
- CBNumber
- CB9787670
- Molecular Formula
- C39H51N5O6
- Formula Weight
- 685.85214
- MOL File
- 184162-64-9.mol
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SR 142948 Property
- Boiling point:
- 824.7±65.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- Soluble to 75 mM in DMSO and to 25 mM in water
- form
- Powder
- pka
- 3.28±0.20(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 23911
- Product name
- SR 142948
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $75
- Updated
- 2021/12/16
Cayman Chemical
- Product number
- 23911
- Product name
- SR 142948
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $175
- Updated
- 2021/12/16
Cayman Chemical
- Product number
- 23911
- Product name
- SR 142948
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $250
- Updated
- 2021/12/16
Tocris
- Product number
- 2309
- Product name
- SR142948
- Purity
- ≥97%(HPLC)
- Packaging
- 10
- Price
- $298
- Updated
- 2021/12/16
Tocris
- Product number
- 2309
- Product name
- SR142948
- Purity
- ≥97%(HPLC)
- Packaging
- 1
- Price
- $141
- Updated
- 2021/12/16
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SR 142948 Chemical Properties,Usage,Production
Uses
SR 142948 is an antagonist of NT1/NT2 receptors inhibiting bile acid secretion. Neurotensin receptor antagonist.
Definition
ChEBI: 2-[[[5-(2,6-dimethoxyphenyl)-1-[4-[[3-(dimethylamino)propyl-methylamino]-oxomethyl]-2-propan-2-ylphenyl]-3-pyrazolyl]-oxomethyl]amino]-2-adamantanecarboxylic acid is a N-acyl-amino acid.
Biological Activity
Potent non-peptide neurotensin (NT) receptor antagonist that binds with high affinity (IC 50 = 0.32 - 3.96 nM). Attenuates amphetamine-induced hyperactivity and is orally active in vivo .
storage
Store at +4°C
SR 142948 Preparation Products And Raw materials
Raw materials
Preparation Products
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SR 142948 Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77