Fresolimumab

Product Name: Fresolimumab
CAS No.: 948564-73-6
Chemical Name: Fresolimumab
Synonyms: GC1008;Fresolimumab;Fresolimumab (anti-TGFb1);Research Grade Fresolimumab;Research Grade Fresolimumab(DHB91601)
CBNumber: CB98080759
Formula Weight: 0
MOL File: Mol file

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Fresolimumab Property

storage temp.: Store at -80°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Fresolimumab Chemical Properties,Usage,Production

Uses

Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease[1][2][3].

References

[1] Song IW, et al. Targeting TGF-β for treatment of osteogenesis imperfecta. J Clin Invest. 2022 Apr 1;132(7):e152571. DOI:10.1172/JCI152571
[2] Lan Y, et al. Colocalized targeting of TGF-β and PD-L1 by bintrafusp alfa elicits distinct antitumor responses. J Immunother Cancer. 2022 Jul;10(7):e004122. DOI:10.1136/jitc-2021-004122
[3] Oude Munnink TH, et al. PET with the 89Zr-labeled transforming growth factor-β antibody fresolimumab in tumor models. J Nucl Med. 2011 Dec;52(12):2001-8. DOI:10.2967/jnumed.111.092809

Fresolimumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Fresolimumab Suppliers

China 20 United States 1 Global 21

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
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ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
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Guangzhou Hongyuan Chemical Co.,Ltd

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Wuhan Chemstan Biotechnology Co., Ltd.

Tel: 027-65317797 15926423062
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
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Biolab Reagents

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Wuhan Jingkangen Biomedical Technology Co., Ltd

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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Tel: 021-59167510 18117107507
Email: vip@med-life.cn
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948564-73-6, FresolimumabRelated Search:

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Fresolimumab

Research Grade Fresolimumab(DHB91601)

GC1008

Research Grade Fresolimumab

Fresolimumab (anti-TGFb1)

948564-73-6