Pomalidomide-PEG3-NH2

Product Name
Pomalidomide-PEG3-NH2
CAS No.
2380273-74-3
Chemical Name
Pomalidomide-PEG3-NH2
Synonyms
Poma-amide-PEG3-NH2;Pomalidomide-PEG3-NH2;Pomalidomide-amino-PEG3-NH2;Thalidomide-4-amido-C1-PEG3-NH2;2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide;Acetamide, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
CBNumber
CB98286542
Molecular Formula
C21H26N4O8
Formula Weight
462.45
MOL File
2380273-74-3.mol
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Pomalidomide-PEG3-NH2 Property

Boiling point:
760.8±60.0 °C(Predicted)
Density 
1.415±0.06 g/cm3(Predicted)
pka
10.68±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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Pomalidomide-PEG3-NH2 Chemical Properties,Usage,Production

Uses

Pomalidomide-amino-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Pomalidomide-PEG3-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomalidomide-PEG3-NH2 Suppliers

China 9 Global 9
Daicel Chiral Technologies (China)CO.,LTD
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021-50460086-9 15921403865
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+86-21-50462321
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han_yajun@dctc.daicel.com
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China
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Chengdu HuaNa Chemicals Co., Ltd.
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028-86612776; 13699069380
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515238037@qq.com
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China
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Zhengzhou convergence chemical co., LTD
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0371-0371-55153829 18003835034
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2853979819@qq.com
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China
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9998
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Hubei Kele Fine Chemical Co., Ltd
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027-59101668 19945030958
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027-59101668
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2881924765@qq.com
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China
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7938
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Wuhan Augda Biotechnology Co., Ltd
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15071299552
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QQ:262933239
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262933239@qq.com
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China
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7048
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Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
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15387063101
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2881924050@qq.com
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China
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9960
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Xi‘an Deeptech Biotechnology Co.,LTD
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+86-15114901355
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15114901355@163.com
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China
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190
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Henan Mengtai Pharmaceutical Technology Co., Ltd
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176345344 7 17634854698
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1959525201@qq.com
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China
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10000
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Dipag (Weinan) Biotechnology Co., Ltd
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15114901355
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029-85310852
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1002921772@qq.com
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China
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190
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2380273-74-3, Pomalidomide-PEG3-NH2Related Search:

POMALIDOMIDE-PEG2-ALKYNE Pomalidomide-PEG2-NH2 Pomalidomide-PEG6-Alkyne POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG6-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-

  • Pomalidomide-PEG3-NH2
  • Acetamide, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
  • Pomalidomide-amino-PEG3-NH2
  • Poma-amide-PEG3-NH2
  • Thalidomide-4-amido-C1-PEG3-NH2
  • 2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide
  • 2380273-74-3