ChemicalBook > CAS DataBase List > POMALIDOMIDE-PEG2-CO2H
POMALIDOMIDE-PEG2-CO2H
- Product Name
- POMALIDOMIDE-PEG2-CO2H
- CAS No.
- 2140807-17-4
- Chemical Name
- POMALIDOMIDE-PEG2-CO2H
- Synonyms
- NUN 07174;Poma-PEG2-COOH;Pomalidomide-PEG2-COOH;POMALIDOMIDE-PEG2-CO2H;Pomalidomide-PEG2-Acid;Pomalidomide 4'-PEG2-acid;Thalidomide-4-NH-PEG2-COOH;Thalidomide-NH-PEG2-C2-COOH;Pomalidomide-PEG2-CO2H >=98%;Thalidomide-4-NH-PEG2-C2-COOH
- CBNumber
- CB44744117
- Molecular Formula
- C20H23N3O8
- Formula Weight
- 433.41
- MOL File
- 2140807-17-4.mol
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POMALIDOMIDE-PEG2-CO2H Property
- Boiling point:
- 744.6±60.0 °C(Predicted)
- Density
- 1.456±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- powder or crystals
- pka
- 4.28±0.10(Predicted)
- color
- White to yellow
- InChI
- 1S/C20H23N3O8/c24-15-5-4-14(18(27)22-15)23-19(28)12-2-1-3-13(17(12)20(23)29)21-7-9-31-11-10-30-8-6-16(25)26/h1-3,14,21H,4-11H2,(H,25,26)(H,22,24,27)
- InChIKey
- NKISJPXMSOQWER-UHFFFAOYSA-N
- SMILES
- O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3NCCOCCOCCC(O)=O)=O)NC1=O
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Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 901526
- Product name
- Pomalidomide-PEG2-CO2H
- Purity
- 95%
- Packaging
- 50MG
- Price
- $525
- Updated
- 2025/07/31
Iris Biotech GmbH
- Product number
- PTC1160
- Product name
- Pomalidomide-PEG2-COOH
- Packaging
- 50mg
- Price
- $702
- Updated
- 2021/12/16
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POMALIDOMIDE-PEG2-CO2H Chemical Properties,Usage,Production
Uses
Protein degrader builiding block Pomalidomide-PEG2-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
reaction suitability
reactivity: amine reactive
reagent type: ligand-linker conjugate
storage
Store at -20°C
POMALIDOMIDE-PEG2-CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
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POMALIDOMIDE-PEG2-CO2H Suppliers
- Tel
- 021-50460086-9 15921403865
- Fax
- +86-21-50462321
- han_yajun@dctc.daicel.com
- Country
- China
- ProdList
- 7440
- Advantage
- 65
- Tel
- 0510-83588313-811 18800520310
- sales@chemshuttle.com
- Country
- China
- ProdList
- 2999
- Advantage
- 62
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25700
- Advantage
- 65
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 40000
- Advantage
- 60
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 9531
- Advantage
- 58
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15491
- Advantage
- 58
- Tel
- 021-61469567 13482353728
- Fax
- 021-61161605
- sales@fdc-chemical.com
- Country
- China
- ProdList
- 9804
- Advantage
- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
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View Lastest Price from POMALIDOMIDE-PEG2-CO2H manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Pomalidomide-PEG2-COOH 2140807-17-4
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >99.00%
- Supply Ability
- 100mg
- Release date
- 2024-04-01
2140807-17-4, POMALIDOMIDE-PEG2-CO2HRelated Search:
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