ChemicalBook > CAS DataBase List > POMALIDOMIDE-PEG2-CO2H
POMALIDOMIDE-PEG2-CO2H
- Product Name
- POMALIDOMIDE-PEG2-CO2H
- CAS No.
- 2140807-17-4
- Chemical Name
- POMALIDOMIDE-PEG2-CO2H
- Synonyms
- NUN 07174;Poma-PEG2-COOH;Pomalidomide-PEG2-COOH;POMALIDOMIDE-PEG2-CO2H;Pomalidomide-PEG2-Acid;Thalidomide-4-NH-PEG2-COOH;Thalidomide-NH-PEG2-C2-COOH;Pomalidomide-PEG2-CO2H >=98%;Thalidomide-4-NH-PEG2-C2-COOH;3-[2-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]ethoxy]propanoic Acid
- CBNumber
- CB44744117
- Molecular Formula
- C20H23N3O8
- Formula Weight
- 433.41
- MOL File
- 2140807-17-4.mol
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POMALIDOMIDE-PEG2-CO2H Property
- Boiling point:
- 744.6±60.0 °C(Predicted)
- Density
- 1.456±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- powder or crystals
- pka
- 4.28±0.10(Predicted)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 901526
- Product name
- Pomalidomide-PEG2-CO2H
- Purity
- 95%
- Packaging
- 50MG
- Price
- $1070
- Updated
- 2023/06/20
Iris Biotech GmbH
- Product number
- PTC1160
- Product name
- Pomalidomide-PEG2-COOH
- Packaging
- 50mg
- Price
- $702
- Updated
- 2021/12/16
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POMALIDOMIDE-PEG2-CO2H Chemical Properties,Usage,Production
Uses
Protein degrader builiding block Pomalidomide-PEG2-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
storage
Store at -20°C
POMALIDOMIDE-PEG2-CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
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POMALIDOMIDE-PEG2-CO2H Suppliers
- Tel
- 15114901355
- 15114901355@163.com
- Country
- China
- ProdList
- 183
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- 58
- Tel
- 021-50460086-9 15921403865
- Fax
- +86-21-50462321
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- China
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- 65
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- 0510-83588313-802 18800520310;
- sales@chemshuttle.com
- Country
- China
- ProdList
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- 18521735133 18521732826;
- Fax
- 021-50323701
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- China
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- 65
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- 021-61415566 800-8193336
- orderCN@merckgroup.com
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- China
- ProdList
- 51471
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- 80
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- QQ:65489617 15618227136
- Fax
- 21-5161 9052
- info@SuperLan-chem.com
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- China
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- 4006653949
- Fax
- QQ: 2136646215
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- Country
- China
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- Tel
- 025-66113011 18112977050
- Fax
- (5)02557626880
- cb6@aikonchem.com
- Country
- China
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- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
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- Tel
- 13504435624
- 1927928688@qq.com
- Country
- China
- ProdList
- 1293
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View Lastest Price from POMALIDOMIDE-PEG2-CO2H manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Pomalidomide-PEG2-COOH 2140807-17-4
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >99.00%
- Supply Ability
- 100mg
- Release date
- 2024-04-01
2140807-17-4, POMALIDOMIDE-PEG2-CO2HRelated Search:
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG2-N3
Pomalidomide-PEG4-azide
Pomalidomide-PEG2-butyl iodide
E3 Ligase Ligand-Linker Conjugates 22
4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Pomalidomide-PEG4-CO2H
E3 Ligase Ligand-Linker Conjugates 1
Pomalidomide-PEG1-azide
Pomalidomide-PEG5-CO2H
POMALIDOMIDE-PEG1-CO2H
Pomalidomide-O-C4-NH2
Pomalidomide-PEG3-N3
Pomalidomide-PEG6-butyl iodide
Pomalidomide-PEG3-CO2H
E3 ligase Ligand-Linker Conjugates 50
Pomalidomide-PEG3-NH2
POMALIDOMIDE-PEG2-ALKYNE