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E3 Ligase Ligand-Linker Conjugates 22

Product Name
E3 Ligase Ligand-Linker Conjugates 22
CAS No.
2225940-52-1
Chemical Name
E3 Ligase Ligand-Linker Conjugates 22
Synonyms
Pomalidomide-PEG4-C2-NH2;Cereblon Ligand-Linker Conjugates 8;E3 Ligase Ligand-Linker Conjugates 22;Pomalidomide-PEG4-C2-NH2, 10 mM in DMSO;4-((14-amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;inhibit,PomalidomidePEG4C2NH2,E3 Ligase Ligand-Linker Conjugates,Inhibitor,Pomalidomide PEG4 C2 NH2;1H-Isoindole-1,3(2H)-dione, 4-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-;4-(15-amino-4,7,10,13-tetraoxa-1-azapentadecan-1-yl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione;4-((14-Amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione?, Pomalidomide-PEG4-C2-NH2
CBNumber
CB74797048
Molecular Formula
C23H32N4O8
Formula Weight
492.52
MOL File
2225940-52-1.mol
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E3 Ligase Ligand-Linker Conjugates 22 Property

Boiling point:
714.3±60.0 °C(Predicted)
Density 
1.335±0.06 g/cm3(Predicted)
pka
10.74±0.40(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb572875
Product name
E3 Ligase Ligand-Linker Conjugates 22
Purity
>97%
Packaging
100mg
Price
$838.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb572875
Product name
E3 Ligase Ligand-Linker Conjugates 22
Purity
>97%
Packaging
250mg
Price
$1654.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb572875
Product name
E3 Ligase Ligand-Linker Conjugates 22
Purity
>97%
Packaging
1g
Price
$3282.7
Updated
2021/12/16
DC Chemicals
Product number
DC12141
Product name
E3LigaseLigand-LinkerConjugates22
Purity
>97%
Packaging
1g
Price
$2200
Updated
2021/12/16
DC Chemicals
Product number
DC12141
Product name
E3LigaseLigand-LinkerConjugates22
Purity
>97%
Packaging
250mg
Price
$1100
Updated
2021/12/16
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E3 Ligase Ligand-Linker Conjugates 22 Chemical Properties,Usage,Production

Uses

Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

IC 50

Cereblon

References

[1] Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1.

E3 Ligase Ligand-Linker Conjugates 22 Preparation Products And Raw materials

Raw materials

Preparation Products

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E3 Ligase Ligand-Linker Conjugates 22 Suppliers

Aikon International Limited
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025-58859352 18068836627
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China
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China
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+1-781-999-5354; +17819995354
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United States
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QQ 3610331285
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Henan Alpha Chemical Co., Ltd.
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2225940-52-1, E3 Ligase Ligand-Linker Conjugates 22Related Search:


  • E3 Ligase Ligand-Linker Conjugates 22
  • Pomalidomide-PEG4-C2-NH2
  • Cereblon Ligand-Linker Conjugates 8
  • 1H-Isoindole-1,3(2H)-dione, 4-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-
  • 4-((14-amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
  • inhibit,PomalidomidePEG4C2NH2,E3 Ligase Ligand-Linker Conjugates,Inhibitor,Pomalidomide PEG4 C2 NH2
  • 4-(15-amino-4,7,10,13-tetraoxa-1-azapentadecan-1-yl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 4-((14-Amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione?, Pomalidomide-PEG4-C2-NH2
  • Pomalidomide-PEG4-C2-NH2, 10 mM in DMSO
  • 2225940-52-1
  • peg