E3 ligase Ligand-Linker Conjugates 13

Product Name: E3 ligase Ligand-Linker Conjugates 13
CAS No.: 2010159-45-0
Chemical Name: E3 ligase Ligand-Linker Conjugates 13
Synonyms: VH032-PEG2-N3;S)-AHPC-PEG2-N3;(S,R,S)-AHPC-PEG2-azide;VHL Ligand-Linker Conjugates 6;E3 ligase Ligand-Linker Conjugates 13;E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCPEG2N3,Inhibitor,inhibit,(S,R,S)-AHPC-PEG-2-N3,(S,R,S) AHPC PEG2 N3;L-Prolinamide, N-[2-[2-(2-azidoethoxy)ethoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(2S,4R)-1-((S)-2-(2-(2-(2-azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-((S)-2-(2-(2-(2-Azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, Crosslinker?E3 ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader, VH032 conjugate
CBNumber: CB93386465
Molecular Formula: C28H39N7O6S
Formula Weight: 601.72
MOL File: 2010159-45-0.mol

More

Less

E3 ligase Ligand-Linker Conjugates 13 Property

storage temp.: 2-8°C
form: Liquid
color: Off-white to yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 904813
Product name: (S,R,S)-AHPC-PEG2-azide
Packaging: 50MG
Price: $1290
Updated: 2023/06/20

Iris Biotech GmbH

Product number: PTC1600
Product name: (S,R,S)-AHPC-PEG2-N3
Packaging: 50mg
Price: $634.5
Updated: 2021/12/16

More

Less

E3 ligase Ligand-Linker Conjugates 13 Chemical Properties,Usage,Production

Uses

Protein degrader builiding block (S,R,S)-AHPC-PEG2-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

E3 ligase Ligand-Linker Conjugates 13 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

E3 ligase Ligand-Linker Conjugates 13 Suppliers

China 17 United States 1 Global 18

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4825
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1458
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 39995
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62075
Advantage: 58

Changzhou Bojia Biomedical Technology Co., Ltd.

Tel: 2122619822
Email: czbjpharma@126.com
Country: China
ProdList: 18478
Advantage: 58

More

Less

View Lastest Price from E3 ligase Ligand-Linker Conjugates 13 manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: (S,R,S)-AHPC-PEG2-azide 2010159-45-0
Price: US $0.00/mg
Min. Order: 100mg
Purity: >99.00%
Supply Ability: 100mg
Release date: 2024-04-01

2010159-45-0, E3 ligase Ligand-Linker Conjugates 13Related Search:

E3 ligase Ligand-Linker Conjugates 50 E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate E3 ligase Ligand-Linker Conjugates 4 E3 ligase Ligand-Linker Conjugates 6 E3 Ligase Ligand-Linker Conjugates 19 E3 ligase Ligand-Linker Conjugates 7 Free Base E3 Ligase Ligand-Linker Conjugates 22 E3 ligase Ligand-Linker Conjugates 11

E3 ligase Ligand-Linker Conjugates 13

(S,R,S)-AHPC-PEG2-azide

VHL Ligand-Linker Conjugates 6

VH032-PEG2-N3

S)-AHPC-PEG2-N3

E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCPEG2N3,Inhibitor,inhibit,(S,R,S)-AHPC-PEG-2-N3,(S,R,S) AHPC PEG2 N3

(2S,4R)-1-((S)-2-(2-(2-(2-Azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, Crosslinker?E3 ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader, VH032 conjugate

(2S,4R)-1-((S)-2-(2-(2-(2-azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

L-Prolinamide, N-[2-[2-(2-azidoethoxy)ethoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

2010159-45-0