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E3 ligase Ligand-Linker Conjugates 6

Product Name
E3 ligase Ligand-Linker Conjugates 6
CAS No.
2097973-72-1
Chemical Name
E3 ligase Ligand-Linker Conjugates 6
Synonyms
VH032-PEG2-NH2 hydrochloride;S)-AHPC-PEG2-NH2 hydrochloride;(S,R,S)-AHPC-PEG2-NH2 hydrochloride;E3 ligase Ligand-Linker Conjugates 6;(S,R,S)-AHPC-PEG2-NH2 hydrochloride >=95%;VHL Ligand-Linker Conjugates 3 hydrochloride;(S,R,S)-AHPC-PEG2-NH2 hydrochloride E3 ligase Ligand-Linker Conjugates 6);(2S,4R)-1-((S)-2-(2-(2-(2-aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride;inhibit,E3 Ligase Ligand-Linker Conjugates,Inhibitor,VHL Ligand-Linker Conjugates 3,(S,R,S) AHPC PEG2 NH2 hydrochloride,(S,R,S)AHPCPEG2NH2 hydrochloride,(S,R,S)-AHPC-PEG-2-NH2 hydrochloride;(2S,4R)-1-((S)-2-(2-(2-(2-Aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride, Crosslinker?E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader, VH032 conjugate
CBNumber
CB83386473
Molecular Formula
C28H42ClN5O6S
Formula Weight
612.18
MOL File
2097973-72-1.mol
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E3 ligase Ligand-Linker Conjugates 6 Property

storage temp. 
2-8°C
form 
Solid
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901488
Product name
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
Purity
≥95%
Packaging
50MG
Price
$688
Updated
2023/06/20
Iris Biotech GmbH
Product number
PTC1320
Product name
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
Packaging
50mg
Price
$499.5
Updated
2021/12/16
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E3 ligase Ligand-Linker Conjugates 6 Chemical Properties,Usage,Production

Uses

Protein degrader builiding block (S,R,S)-AHPC-PEG2-NH2 (HCl salt) enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with pendant amine for reactivity with a carboxyl group on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant amine, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

E3 ligase Ligand-Linker Conjugates 6 Preparation Products And Raw materials

Raw materials

Preparation Products

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E3 ligase Ligand-Linker Conjugates 6 Suppliers

ChemShuttle, Inc.
Tel
0510-83588313-802 18800520310;
Email
sales@chemshuttle.com
Country
China
ProdList
2996
Advantage
62
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15951
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4824
Advantage
58
SuZhou Medinoah Co.,LTD.
Tel
0512-69561983 13914027025
Fax
0512-69561982
Email
zhang_q@medinoah.com
Country
China
ProdList
4007
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1456
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
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View Lastest Price from E3 ligase Ligand-Linker Conjugates 6 manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
(S,R,S)-AHPC-PEG2-NH2 hydrochloride 2097973-72-1
Price
US $0.00/mg
Min. Order
100mg
Purity
>98.00%
Supply Ability
100mg
Release date
2024-04-01

2097973-72-1, E3 ligase Ligand-Linker Conjugates 6Related Search:


  • E3 ligase Ligand-Linker Conjugates 6
  • (S,R,S)-AHPC-PEG2-NH2 hydrochloride
  • VH032-PEG2-NH2 hydrochloride
  • VHL Ligand-Linker Conjugates 3 hydrochloride
  • (S,R,S)-AHPC-PEG2-NH2 hydrochloride >=95%
  • (S,R,S)-AHPC-PEG2-NH2 hydrochloride E3 ligase Ligand-Linker Conjugates 6)
  • (2S,4R)-1-((S)-2-(2-(2-(2-aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
  • S)-AHPC-PEG2-NH2 hydrochloride
  • inhibit,E3 Ligase Ligand-Linker Conjugates,Inhibitor,VHL Ligand-Linker Conjugates 3,(S,R,S) AHPC PEG2 NH2 hydrochloride,(S,R,S)AHPCPEG2NH2 hydrochloride,(S,R,S)-AHPC-PEG-2-NH2 hydrochloride
  • (2S,4R)-1-((S)-2-(2-(2-(2-Aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride, Crosslinker?E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader, VH032 conjugate
  • 2097973-72-1