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E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate

Product Name
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
CAS No.
1950635-14-9
Chemical Name
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
Synonyms
Thalidomide-O-amido-C6-NH2 TFA;E3 ligase Ligand-Linker Conjugates 25;Cereblon Ligand-Linker Conjugates 11 TFA;E3 Ligase Ligand-Linker Conjugates 25 TFA;Thalidomide-O-amido-C6-NH2 TFA, 10 mM in DMSO;E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate;N-(6-aminohexyl)-2-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]oxy-acetamide;N-(6-aminohexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3- dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetate;N-(6-Aminohexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate;Inhibitor,E3 Ligase Ligand-Linker Conjugates,E3 Ligase Ligand-Linker Conjugates 25,inhibit,Cereblon Ligand-Linker Conjugates 11,Thalidomide O amido C6 NH2 TFA,ThalidomideOamidoC6NH2 TFA,Thalidomide-O-amido-C-6-NH2 TFA
CBNumber
CB84797050
Molecular Formula
C23H27F3N4O8
Formula Weight
544.48
MOL File
1950635-14-9.mol
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E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate Property

storage temp. 
2-8°C, stored under nitrogen
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb572898
Product name
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
Packaging
100mg
Price
$986
Updated
2021/12/16
Biorbyt Ltd
Product number
orb572898
Product name
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
Packaging
250mg
Price
$1949.9
Updated
2021/12/16
Biorbyt Ltd
Product number
orb572898
Product name
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
Packaging
1g
Price
$3876
Updated
2021/12/16
DC Chemicals
Product number
DC12181
Product name
E3LigaseLigand-LinkerConjugates25Trifluoroacetate
Purity
>98%
Packaging
100mg
Price
$650
Updated
2021/12/16
DC Chemicals
Product number
DC12181
Product name
E3LigaseLigand-LinkerConjugates25Trifluoroacetate
Purity
>98%
Packaging
1g
Price
$2600
Updated
2021/12/16
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E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate Chemical Properties,Usage,Production

Uses

Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

References

[1] Bradner J, et al. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses. WO 2017024318 A1

E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate Suppliers

China 28 United States 2 Global 30
Aikon International Limited
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13504435624
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1950635-14-9, E3 Ligase Ligand-Linker Conjugates 25 TrifluoroacetateRelated Search:

N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt E3 ligase Ligand-Linker Conjugates 17 E3 ligase Ligand-Linker Conjugates 14 E3 ligase Ligand-Linker Conjugates 5 Free Base Thalidomide-O-amido-C3-NH2 (TFA) 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione E3 ligase Ligand-Linker Conjugates 50 E3 Ligase Ligand-Linker Conjugates 21 E3 ligase Ligand-Linker Conjugates 13 E3 ligase Ligand-Linker Conjugates 4 E3 ligase Ligand-Linker Conjugates 6 E3 Ligase Ligand-Linker Conjugates 19 E3 ligase Ligand-Linker Conjugates 7 Free Base E3 ligase Ligand-Linker Conjugates 11 E3 Ligase Ligand-Linker Conjugates 22 E3 Ligase Ligand-Linker Conjugates 20

  • E3 ligase Ligand-Linker Conjugates 25
  • E3 Ligase Ligand-Linker Conjugates 25 TFA
  • Thalidomide-O-amido-C6-NH2 TFA
  • E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
  • Cereblon Ligand-Linker Conjugates 11 TFA
  • N-(6-Aminohexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate
  • Inhibitor,E3 Ligase Ligand-Linker Conjugates,E3 Ligase Ligand-Linker Conjugates 25,inhibit,Cereblon Ligand-Linker Conjugates 11,Thalidomide O amido C6 NH2 TFA,ThalidomideOamidoC6NH2 TFA,Thalidomide-O-amido-C-6-NH2 TFA
  • N-(6-aminohexyl)-2-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]oxy-acetamide
  • N-(6-aminohexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3- dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetate
  • Thalidomide-O-amido-C6-NH2 TFA, 10 mM in DMSO
  • 1950635-14-9
  • C46H53F6N8O16