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E3 Ligase Ligand-Linker Conjugates 20

Product Name
E3 Ligase Ligand-Linker Conjugates 20
CAS No.
1950635-15-0
Chemical Name
E3 Ligase Ligand-Linker Conjugates 20
Synonyms
Thalidomide-O-amido-C8-NH2;Cereblon Ligand-Linker Conjugates 2;E3 Ligase Ligand-Linker Conjugates 20;N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide;N-(8-aminooctyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide;Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide?, Thalidomide-O-amido-C8-NH2
CBNumber
CB13386469
Molecular Formula
C23H30N4O6
Formula Weight
458.51
MOL File
1950635-15-0.mol
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E3 Ligase Ligand-Linker Conjugates 20 Property

Boiling point:
762.8±60.0 °C(Predicted)
Density 
1.295±0.06 g/cm3(Predicted)
pka
10.68±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

CSNpharm
Product number
CSN23772
Product name
E3LigaseLigand-LinkerConjugates20
Packaging
100mg
Price
$298
Updated
2021/12/16
CSNpharm
Product number
CSN23772
Product name
E3LigaseLigand-LinkerConjugates20
Packaging
250mg
Price
$521
Updated
2021/12/16
DC Chemicals
Product number
027580
Product name
E3LigaseLigand-LinkerConjugates20
Packaging
001
Price
$550
Updated
2021/12/16
DC Chemicals
Product number
027580
Product name
E3LigaseLigand-LinkerConjugates20
Packaging
002
Price
$850
Updated
2021/12/16
DC Chemicals
Product number
027580
Product name
E3LigaseLigand-LinkerConjugates20
Packaging
003
Price
$1800
Updated
2021/12/16
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E3 Ligase Ligand-Linker Conjugates 20 Chemical Properties,Usage,Production

Uses

Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

References

[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

E3 Ligase Ligand-Linker Conjugates 20 Preparation Products And Raw materials

Raw materials

Preparation Products

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E3 Ligase Ligand-Linker Conjugates 20 Suppliers

Jilin Province Woda Biotechnology Co., Ltd.
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1950635-15-0, E3 Ligase Ligand-Linker Conjugates 20Related Search:


  • E3 Ligase Ligand-Linker Conjugates 20
  • Cereblon Ligand-Linker Conjugates 2
  • Thalidomide-O-amido-C8-NH2
  • N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
  • Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
  • N-(8-aminooctyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide
  • N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide?, Thalidomide-O-amido-C8-NH2
  • 1950635-15-0