ChemicalBook > CAS DataBase List > E3 Ligase Ligand-Linker Conjugates 20
E3 Ligase Ligand-Linker Conjugates 20
- Product Name
- E3 Ligase Ligand-Linker Conjugates 20
- CAS No.
- 1950635-15-0
- Chemical Name
- E3 Ligase Ligand-Linker Conjugates 20
- Synonyms
- Thalidomide-O-amido-C8-NH2;Cereblon Ligand-Linker Conjugates 2;E3 Ligase Ligand-Linker Conjugates 20;N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide;N-(8-aminooctyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide;Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide?, Thalidomide-O-amido-C8-NH2
- CBNumber
- CB13386469
- Molecular Formula
- C23H30N4O6
- Formula Weight
- 458.51
- MOL File
- 1950635-15-0.mol
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E3 Ligase Ligand-Linker Conjugates 20 Property
- Boiling point:
- 762.8±60.0 °C(Predicted)
- Density
- 1.295±0.06 g/cm3(Predicted)
- pka
- 10.68±0.40(Predicted)
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N-Bromosuccinimide Price
CSNpharm
- Product number
- CSN23772
- Product name
- E3LigaseLigand-LinkerConjugates20
- Packaging
- 100mg
- Price
- $298
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN23772
- Product name
- E3LigaseLigand-LinkerConjugates20
- Packaging
- 250mg
- Price
- $521
- Updated
- 2021/12/16
DC Chemicals
- Product number
- 027580
- Product name
- E3LigaseLigand-LinkerConjugates20
- Packaging
- 001
- Price
- $550
- Updated
- 2021/12/16
DC Chemicals
- Product number
- 027580
- Product name
- E3LigaseLigand-LinkerConjugates20
- Packaging
- 002
- Price
- $850
- Updated
- 2021/12/16
DC Chemicals
- Product number
- 027580
- Product name
- E3LigaseLigand-LinkerConjugates20
- Packaging
- 003
- Price
- $1800
- Updated
- 2021/12/16
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E3 Ligase Ligand-Linker Conjugates 20 Chemical Properties,Usage,Production
Uses
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
IC 50
Cereblon
References
[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.
E3 Ligase Ligand-Linker Conjugates 20 Preparation Products And Raw materials
Raw materials
Preparation Products
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E3 Ligase Ligand-Linker Conjugates 20 Suppliers
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1950635-15-0, E3 Ligase Ligand-Linker Conjugates 20Related Search:
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
E3 Ligase Ligand-Linker Conjugates 22
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
Thalidomide-linker 14
N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)-
Cereblon Ligand 1
E3 Ligase Ligand-Linker Conjugates 21
E3 Ligase Ligand-Linker Conjugates 19
Thalidomide-O-PEG4-Propargyl
Thalidomide-linker 10
Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-
Thalidomide-O-amido-C4-NH2 hydrochloride
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
Thalidomide-O-amido-C8-NH2 hydrochloride
Thalidomide-O-PEG4-Boc
tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate
E3 Ligase Ligand-Linker Conjugates 24 (TFA)