Thalidomide-O-amido-C4-NH2 hydrochloride

Product Name: Thalidomide-O-amido-C4-NH2 hydrochloride
CAS No.: 2245697-86-1
Chemical Name: Thalidomide-O-amido-C4-NH2 hydrochloride
Synonyms: Thalidomide-linker 3;-oxyacetamide-alkylC4-amine;Thalidomide-O-amido-C4-NH2 hydrochloride;N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
CBNumber: CB66127046
Molecular Formula: C19H23ClN4O6
Formula Weight: 438.87
MOL File: 2245697-86-1.mol

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Thalidomide-O-amido-C4-NH2 hydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

A1 Biochem Labs

Product number: 6591788
Product name: N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamidehydrochloride
Purity: 95%
Packaging: 1g
Price: $1250
Updated: 2021/12/16

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Thalidomide-O-amido-C4-NH2 hydrochloride Chemical Properties,Usage,Production

Uses

Thalidomide-O-amido-C4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression.J Med Chem. 2018 Jan 25;61(2):462-481. DOI:10.1021/acs.jmedchem.6b01816
[2] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

Thalidomide-O-amido-C4-NH2 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Thalidomide-O-amido-C4-NH2 hydrochloride Suppliers

China 24 United States 2 Global 26

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View Lastest Price from Thalidomide-O-amido-C4-NH2 hydrochloride manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Thalidomide-O-amido-C4-NH2 hydrochloride 2245697-86-1
Price: US $0.00/mg
Min. Order: 100mg
Purity: >98.00%
Supply Ability: 100mg
Release date: 2024-04-01

2245697-86-1, Thalidomide-O-amido-C4-NH2 hydrochlorideRelated Search:

N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Thalidomide-O-C6-NH2 Thalidomide-O-C6-NH2 TFA Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Thalidomide-O-amido-C3-NH2 (TFA) 1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)- Cereblon Ligand 1 E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-PEG4-Propargyl Thalidomide-linker 10 Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-O-amido-C8-NH2 hydrochloride Thalidomide-O-PEG4-Boc tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate Thalidomide-linker 13 E3 Ligase Ligand-Linker Conjugates 24 (TFA)

Thalidomide-O-amido-C4-NH2 hydrochloride

-oxyacetamide-alkylC4-amine

Thalidomide-linker 3

N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride

2245697-86-1