Thalidomide-O-amido-C4-NH2 hydrochloride

Product Name: Thalidomide-O-amido-C4-NH2 hydrochloride
CAS No.: 2245697-86-1
Chemical Name: Thalidomide-O-amido-C4-NH2 hydrochloride
Synonyms: Thalidomide-linker 3;-oxyacetamide-alkylC4-amine;Thalidomide-O-amido-C4-NH2 hydrochloride;N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride;Acetamide, N-(4-aminobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)
CBNumber: CB66127046
Molecular Formula: C19H23ClN4O6
Formula Weight: 438.87
MOL File: 2245697-86-1.mol

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Thalidomide-O-amido-C4-NH2 hydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

A1 Biochem Labs

Product number: 6591788
Product name: N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamidehydrochloride
Purity: 95%
Packaging: 1g
Price: $1250
Updated: 2021/12/16

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Thalidomide-O-amido-C4-NH2 hydrochloride Chemical Properties,Usage,Production

Uses

Thalidomide-O-amido-C4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression.J Med Chem. 2018 Jan 25;61(2):462-481. DOI:10.1021/acs.jmedchem.6b01816
[2] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

Thalidomide-O-amido-C4-NH2 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Thalidomide-O-amido-C4-NH2 hydrochloride Suppliers

China 27 United States 2 Global 29

Sichuan Wei Keqi Biological Technology Co., Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

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View Lastest Price from Thalidomide-O-amido-C4-NH2 hydrochloride manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Thalidomide-O-amido-C4-NH2 hydrochloride 2245697-86-1
Price: US $0.00/mg
Min. Order: 100mg
Purity: >98.00%
Supply Ability: 100mg
Release date: 2024-04-01

2245697-86-1, Thalidomide-O-amido-C4-NH2 hydrochlorideRelated Search:

N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Thalidomide-O-C6-NH2 Thalidomide-O-C6-NH2 TFA Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Thalidomide-O-amido-C3-NH2 (TFA) 1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)- Cereblon Ligand 1 E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-PEG4-Propargyl Thalidomide-linker 10 Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-O-amido-C8-NH2 hydrochloride Thalidomide-O-PEG4-Boc tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate Thalidomide-linker 13 E3 Ligase Ligand-Linker Conjugates 24 (TFA)

Thalidomide-O-amido-C4-NH2 hydrochloride

-oxyacetamide-alkylC4-amine

Thalidomide-linker 3

N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride

Acetamide, N-(4-aminobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)

2245697-86-1