ChemicalBook > CAS DataBase List > Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

Product Name
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
CAS No.
2245697-85-0
Chemical Name
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
Synonyms
-oxyacetamide-PEG4-amine;Thalidomide-O-C1-amido-PEG4-C2-NH2 HCl;Thalidomide-O-amido-PEG4-NH2 hydrochloride;Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride;N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
CBNumber
CB26127048
Molecular Formula
C25H35ClN4O10
Formula Weight
587.02
MOL File
2245697-85-0.mol
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Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Property

storage temp. 
2-8°C, sealed storage, away from moisture
solubility 
Soluble in DMSO
form 
Oil
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Arctom
Product number
AS706964
Product name
N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamidehydrochloride
Purity
98%
Packaging
1mg
Price
$23
Updated
2021/12/16
Arctom
Product number
AS706964
Product name
N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamidehydrochloride
Purity
98%
Packaging
5mg
Price
$40
Updated
2021/12/16
CSNpharm
Product number
CSN24768
Product name
Thalidomide-linker2
Packaging
5mg
Price
$44
Updated
2021/12/16
Arctom
Product number
AS706964
Product name
N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamidehydrochloride
Purity
98%
Packaging
10mg
Price
$69
Updated
2021/12/16
Arctom
Product number
AS706964
Product name
N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamidehydrochloride
Purity
98%
Packaging
25mg
Price
$124
Updated
2021/12/16
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Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Chemical Properties,Usage,Production

Uses

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO2016105518A1.

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Suppliers

Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7471
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65
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7778
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56
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
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60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
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58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1615
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Shandong Territorial sea Biological Technology Co., LTD
Tel
15092083467
Email
18660263263@163.com
Country
China
ProdList
2810
Advantage
58
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View Lastest Price from Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Thalidomide-O-amido-PEG4-NH2 hydrochloride 2245697-85-0
Price
US $0.00/mg
Min. Order
100mg
Purity
>96.00%
Supply Ability
100mg
Release date
2024-04-01