Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride

Product Name: Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
CAS No.: 2245697-84-9
Chemical Name: Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
Synonyms: -ether-PEG3-amine;Thalidomide 4’-oxyacetamide-PEG3-amine;-oxyacetamide-alkylC8-amine;Thalidomide-O-amido-PEG3-C2-NH2 HCl;Thalidomide 4'-oxyacetamide-PEG3-amine;Thalidomide-O-amido-PEG3-NH2 hydrochloride;Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride;N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride;Acetamide,?N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)
CBNumber: CB56127049
Molecular Formula: C23H31ClN4O9
Formula Weight: 542.97
MOL File: 2245697-84-9.mol

More

Less

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: Off-white to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Chemical Properties,Usage,Production

Uses

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Methods to induce targeted protein degradation through bifunctional molecules. WO2017007612A1.

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Suppliers

China 23 United States 3 Global 26

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39999
Advantage: 60

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7777
Advantage: 56

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 89689
Advantage: 60

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1636
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

Shandong Territorial sea Biological Technology Co., LTD

Tel: 15092083467
Email: 18660263263@163.com
Country: China
ProdList: 2827
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 39807
Advantage: 58

More

Less

View Lastest Price from Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Thalidomide-O-amido-PEG3-NH2 hydrochloride 2245697-84-9
Price: US $0.00/mg
Min. Order: 250mg
Purity: >98.00%
Supply Ability: 250mg
Release date: 2024-04-01

2245697-84-9, Thalidomide-O-amido-PEG3-C2-NH2 hydrochlorideRelated Search:

N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Thalidomide-O-C6-NH2 Thalidomide-O-C6-NH2 TFA Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Thalidomide-O-amido-C3-NH2 (TFA) 1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)- Cereblon Ligand 1 E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-PEG4-Propargyl Thalidomide-linker 10 Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Thalidomide-O-amido-C4-NH2 hydrochloride Thalidomide-O-amido-C8-NH2 hydrochloride Thalidomide-O-PEG4-Boc tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate Thalidomide-linker 13 E3 Ligase Ligand-Linker Conjugates 24 (TFA)

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride

-ether-PEG3-amine

Thalidomide 4&rsquo

-oxyacetamide-alkylC8-amine

-oxyacetamide-PEG3-amine

Thalidomide-O-amido-PEG3-NH2 hydrochloride

N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride

Thalidomide 4'-oxyacetamide-PEG3-amine

Thalidomide-O-amido-PEG3-C2-NH2 HCl

Acetamide,?N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)

2245697-84-9