ChemicalBook > CAS DataBase List > Thalidomide-linker 10
Thalidomide-linker 10
- Product Name
- Thalidomide-linker 10
- CAS No.
- 2341841-02-7
- Chemical Name
- Thalidomide-linker 10
- Synonyms
- Thalidomide-linker 10;Thalidomide-O-amido-C2-NH2;-oxyacetamide-alkylC2-amine;Thalidomide-O-amido-C2-NH2 hydrochloride;Thalidomide 4'-oxyacetamide-alkylC2-amine;Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride;Thalidomide 4'-oxyacetamide-alkyl-C2-amine (hydrochloride);N-(2-aminoethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride;N-(2-Aminoethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride?, Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl
- CBNumber
- CB75985170
- Molecular Formula
- C17H19ClN4O6
- Formula Weight
- 410.81
- MOL File
- 2341841-02-7.mol
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Thalidomide-linker 10 Property
- storage temp.
- 2-8°C, sealed storage, away from moisture and light
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
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Thalidomide-linker 10 Chemical Properties,Usage,Production
Uses
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].
IC 50
Cereblon
storage
Store at -20°C
References
[1] Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020;187:111952. DOI:10.1016/j.ejmech.2019.111952
Thalidomide-linker 10 Preparation Products And Raw materials
Raw materials
Preparation Products
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Thalidomide-linker 10 Suppliers
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View Lastest Price from Thalidomide-linker 10 manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Thalidomide-O-amido-C2-NH2 hydrochloride 2341841-02-7
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >98.00%
- Supply Ability
- 100mg
- Release date
- 2024-04-01
2341841-02-7, Thalidomide-linker 10Related Search:
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1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)-
Cereblon Ligand 1
E3 Ligase Ligand-Linker Conjugates 21
E3 Ligase Ligand-Linker Conjugates 19
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Thalidomide-linker 13
E3 Ligase Ligand-Linker Conjugates 20