Thalidomide-linker 10

Product Name: Thalidomide-linker 10
CAS No.: 2341841-02-7
Chemical Name: Thalidomide-linker 10
Synonyms: Thalidomide-linker 10;Thalidomide-O-amido-C2-NH2;-oxyacetamide-alkylC2-amine;Thalidomide-O-amido-C2-NH2 hydrochloride;Thalidomide 4'-oxyacetamide-alkylC2-amine;Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl;Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride;Thalidomide 4'-oxyacetamide-alkyl-C2-amine (hydrochloride);N-(2-aminoethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride;Acetamide, N-(2-aminoethyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)
CBNumber: CB75985170
Molecular Formula: C17H19ClN4O6
Formula Weight: 410.81
MOL File: 2341841-02-7.mol

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Thalidomide-linker 10 Property

storage temp.: 2-8°C, sealed storage, away from moisture and light
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H312Harmful in contact with skin

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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Thalidomide-linker 10 Chemical Properties,Usage,Production

Uses

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020;187:111952. DOI:10.1016/j.ejmech.2019.111952

Thalidomide-linker 10 Preparation Products And Raw materials

Raw materials

Preparation Products

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Thalidomide-linker 10 Suppliers

China 23 United States 2 Global 25

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
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Email: 3008007409@qq.com
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Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9025
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
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SuZhou Medinoah Co.,LTD.

Tel: 0512-69561983 13914027025
Fax: 0512-69561982
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Shanghai Hongye Biotechnology Co. Ltd

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Jilin Province Woda Biotechnology Co., Ltd.

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Shanghai Haohong Pharmaceutical Co., Ltd.

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Bide Pharmatech Ltd.

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TargetMol Chemicals Inc.

Tel: 4008200310
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Shanghai Easy CDMO Co.,Ltd

Tel: 021-61734564 13854185395;
Email: info@easycdmo.com
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View Lastest Price from Thalidomide-linker 10 manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Thalidomide-O-amido-C2-NH2 hydrochloride 2341841-02-7
Price: US $0.00/mg
Min. Order: 100mg
Purity: >98.00%
Supply Ability: 100mg
Release date: 2024-04-01

2341841-02-7, Thalidomide-linker 10Related Search:

N-(2-fluoro-6-(trifluoromethyl)benzyl)formamide N-(2-fluorophenyl)-4-((1R,5S)-8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)-3-(3-(trifluoromethyl)benzamido)benzamide 1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)- Cereblon Ligand 1 E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-PEG4-Propargyl Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Thalidomide-O-amido-C4-NH2 hydrochloride Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-O-amido-C8-NH2 hydrochloride Thalidomide-O-PEG4-Boc tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate Thalidomide-linker 13 E3 Ligase Ligand-Linker Conjugates 20

Thalidomide-linker 10

-oxyacetamide-alkylC2-amine

Thalidomide-O-amido-C2-NH2

Thalidomide 4'-oxyacetamide-alkyl-C2-amine (hydrochloride)

Thalidomide-O-amido-C2-NH2 hydrochloride

N-(2-aminoethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride

Thalidomide 4'-oxyacetamide-alkylC2-amine

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

N-(2-Aminoethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride?, Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl

Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl

Acetamide, N-(2-aminoethyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)

2341841-02-7