Thalidomide-linker 13
- Product Name
- Thalidomide-linker 13
- CAS No.
- 2204226-02-6
- Chemical Name
- Thalidomide-linker 13
- Synonyms
- Thalidomide-linker 13;-oxyacetamide-PEG1-amine;Thalidomide-O-amido-PEG1-NH2.HCl;Thalidomide-O-amido-PEG-C2-NH2 HCl;Thalidomide-O-C1-amido-PEG-C2-NH2 HCl;Thalidomide 4'-oxyacetamide-PEG1-amine;Thalidomide-O-amido-PEG1-NH2 hydrochloride;Thalidomide-O-amido-PEG-C2-NH2 hydrochloride;Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, 10 mM in DMSO;N-(2-(2-Aminoethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
- CBNumber
- CB15985163
- Molecular Formula
- C19H23ClN4O7
- Formula Weight
- 454.86
- MOL File
- 2204226-02-6.mol
Thalidomide-linker 13 Property
- storage temp.
- 2-8°C, sealed storage, away from moisture
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H312Harmful in contact with skin
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
Thalidomide-linker 13 Chemical Properties,Usage,Production
Uses
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
IC 50
Cereblon
storage
Store at -20°C
References
[1] Chessum NEA, et al. Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766). J Med Chem. 2018 Feb 8;61(3):918-933. DOI:10.1021/acs.jmedchem.7b01406
Thalidomide-linker 13 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Thalidomide-linker 13 manufacturers
- Product
- Thalidomide-O-amido-PEG1-NH2 hydrochloride 2204226-02-6
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >91.00%
- Supply Ability
- 100mg
- Release date
- 2024-04-01