E3 ligase Ligand-Linker Conjugates 17
- Product Name
- E3 ligase Ligand-Linker Conjugates 17
- CAS No.
- 1950635-16-1
- Chemical Name
- E3 ligase Ligand-Linker Conjugates 17
- Synonyms
- E3 ligase Ligand-Linker Conjugates 17;Pomalidomide Related Compound 6 Triflate;Cereblon Ligand -Linker Conjugates 2 TFA;E3 Ligase Ligand-Linker Conjugates 20 (TFA);Thalidomide-O-amido-C8-NH2 trifluoroacetate;N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetate;N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate
- CBNumber
- CB54694701
- Molecular Formula
- C25H31F3N4O8
- Formula Weight
- 572.54
- MOL File
- 1950635-16-1.mol
E3 ligase Ligand-Linker Conjugates 17 Property
- storage temp.
- 2-8°C
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- orb573255
- Product name
- E3 ligase Ligand-Linker Conjugates 17
- Purity
- >98%
- Packaging
- 500mg
- Price
- $1504.5
- Updated
- 2021/12/16
- Product number
- orb573255
- Product name
- E3 ligase Ligand-Linker Conjugates 17
- Purity
- >98%
- Packaging
- 1g
- Price
- $2691.1
- Updated
- 2021/12/16
- Product number
- orb573255
- Product name
- E3 ligase Ligand-Linker Conjugates 17
- Purity
- >98%
- Packaging
- 2g
- Price
- $3876
- Updated
- 2021/12/16
- Product number
- CSN23949
- Product name
- Thalidomide-O-amido-C8-AmineTrifluoroacetate
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A724281
- Product name
- N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide2,2,2-trifluoroacetate
- Purity
- 98%
- Packaging
- 5mg
- Price
- $142
- Updated
- 2021/12/16
E3 ligase Ligand-Linker Conjugates 17 Chemical Properties,Usage,Production
Uses
Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
IC 50
Cereblon
References
[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.
E3 ligase Ligand-Linker Conjugates 17 Preparation Products And Raw materials
Raw materials
Preparation Products
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