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Pomalidomide-PEG5-CO2H

Product Name
Pomalidomide-PEG5-CO2H
CAS No.
2139348-63-1
Chemical Name
Pomalidomide-PEG5-CO2H
Synonyms
Pomalidomide-PEG5-COOH;Pomalidomide-PEG5-CO2H;Pomalidomide 4'-PEG5-acid;POMALIDOMIDE-PEG 5-CO 2 H;Pomalidomide 4'-PEG5-acid;Thalidomide-NH-PEG5-C2-COOH;Pomalidomide-PEG5-CO2H >=98%;Pomalidomide-PEG5-CO2H ISO 9001：2015 REACH;1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12,15-pentaoxaoctadecan-18-oic Acid;1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
CBNumber
CB14846412
Molecular Formula
C26H35N3O11
Formula Weight
565.57
MOL File
2139348-63-1.mol
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Pomalidomide-PEG5-CO2H Property

Boiling point:
791.0±60.0 °C(Predicted)
Density 
1.360±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.28±0.10(Predicted)
form 
Solid-Liquid Mixture
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901828
Product name
Pomalidomide-PEG5-CO2H
Purity
≥95%
Packaging
50MG
Price
$269.2
Updated
2024/03/01
Tocris
Product number
7095
Product name
Pomalidomide4'-PEG5-acid
Purity
≥95%(HPLC)
Packaging
25
Price
$269
Updated
2021/12/16
Iris Biotech GmbH
Product number
PTC1190
Product name
Pomalidomide-PEG5-COOH
Packaging
50mg
Price
$594
Updated
2021/12/16
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Pomalidomide-PEG5-CO2H Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-PEG5-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

storage

Store at -20°C

Pomalidomide-PEG5-CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomalidomide-PEG5-CO2H Suppliers

China 28 India 1 United States 2 Global 31
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4307
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4824
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-0371-55051623 18137891487
Fax
QQ：2853979817
Email
2853979817@qq.com
Country
China
ProdList
9881
Advantage
58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-66110311 13155353615
Email
qzhang@aikonchem.com
Country
China
ProdList
15527
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1388
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22883
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
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View Lastest Price from Pomalidomide-PEG5-CO2H manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Pomalidomide-PEG5-COOH 2139348-63-1
Price
US $0.00/mg
Min. Order
250mg
Purity
>99.00%
Supply Ability
250mg
Release date
2024-04-01

2139348-63-1, Pomalidomide-PEG5-CO2HRelated Search:

Pomalidomide-PEG3-CO2H E3 Ligase Ligand-Linker Conjugates 1 POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG1-azide Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG3-N3 Pomalidomide-PEG6-butyl iodide POMALIDOMIDE-PEG1-CO2H Pomalidomide-PEG3-Amine HCl salt Pomalidomide-PEG4-CO2H 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione E3 Ligase Ligand-Linker Conjugates 22 Pomalidomide-PEG2-butyl iodide Pomalidomide-PEG4-azide Pomalidomide-PEG2-N3 E3 ligase Ligand-Linker Conjugates 50 POMALIDOMIDE-PEG1-ALKYNE

  • POMALIDOMIDE-PEG 5-CO 2 H
  • Pomalidomide-PEG5-CO2H
  • Propanoic acid, 3-[[14-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12-tetraoxatetradec-1-yl]oxy]-
  • Pomalidomide-PEG5-CO2H >=98%
  • Pomalidomide-PEG5-COOH
  • Pomalidomide-PEG5-CO2H ISO 9001：2015 REACH
  • Pomalidomide 4'-PEG5-acid
  • 1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
  • Thalidomide-NH-PEG5-C2-COOH
  • 1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12,15-pentaoxaoctadecan-18-oic Acid
  • Pomalidomide 4'-PEG5-acid
  • 1-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
  • 2139348-63-1
  • peg