ChemicalBook > CAS DataBase List > Pomalidomide-PEG5-CO2H
Pomalidomide-PEG5-CO2H
- Product Name
- Pomalidomide-PEG5-CO2H
- CAS No.
- 2139348-63-1
- Chemical Name
- Pomalidomide-PEG5-CO2H
- Synonyms
- Pomalidomide-PEG5-COOH;Pomalidomide-PEG5-CO2H;Pomalidomide 4'-PEG5-acid;POMALIDOMIDE-PEG 5-CO 2 H;Pomalidomide 4'-PEG5-acid;Thalidomide-NH-PEG5-C2-COOH;Pomalidomide-PEG5-CO2H >=98%;Pomalidomide-PEG5-CO2H ISO 9001：2015 REACH;1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12,15-pentaoxaoctadecan-18-oic Acid;1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
- CBNumber
- CB14846412
- Molecular Formula
- C26H35N3O11
- Formula Weight
- 565.57
- MOL File
- 2139348-63-1.mol
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Pomalidomide-PEG5-CO2H Property
- Boiling point:
- 791.0±60.0 °C(Predicted)
- Density
- 1.360±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.28±0.10(Predicted)
- form
- Solid-Liquid Mixture
- color
- White to yellow
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 901828
- Product name
- Pomalidomide-PEG5-CO2H
- Purity
- ≥95%
- Packaging
- 50MG
- Price
- $269.2
- Updated
- 2024/03/01
Tocris
- Product number
- 7095
- Product name
- Pomalidomide4'-PEG5-acid
- Purity
- ≥95%(HPLC)
- Packaging
- 25
- Price
- $269
- Updated
- 2021/12/16
Iris Biotech GmbH
- Product number
- PTC1190
- Product name
- Pomalidomide-PEG5-COOH
- Packaging
- 50mg
- Price
- $594
- Updated
- 2021/12/16
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Pomalidomide-PEG5-CO2H Chemical Properties,Usage,Production
Uses
Protein degrader builiding block Pomalidomide-PEG5-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
storage
Store at -20°C
Pomalidomide-PEG5-CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
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Pomalidomide-PEG5-CO2H Suppliers
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View Lastest Price from Pomalidomide-PEG5-CO2H manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Pomalidomide-PEG5-COOH 2139348-63-1
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >99.00%
- Supply Ability
- 250mg
- Release date
- 2024-04-01
2139348-63-1, Pomalidomide-PEG5-CO2HRelated Search:
Pomalidomide-PEG3-CO2H
E3 Ligase Ligand-Linker Conjugates 1
POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG1-azide
Pomalidomide-O-C4-NH2
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG3-N3
Pomalidomide-PEG6-butyl iodide
POMALIDOMIDE-PEG1-CO2H
Pomalidomide-PEG3-Amine HCl salt
Pomalidomide-PEG4-CO2H
4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
E3 Ligase Ligand-Linker Conjugates 22
Pomalidomide-PEG2-butyl iodide
Pomalidomide-PEG4-azide
Pomalidomide-PEG2-N3
E3 ligase Ligand-Linker Conjugates 50
POMALIDOMIDE-PEG1-ALKYNE