Pomalidomide-PEG2-N3

Product Name: Pomalidomide-PEG2-N3
CAS No.: 2267306-14-7
Chemical Name: Pomalidomide-PEG2-N3
Synonyms: N3-PEG2-CH2CO-Poma;Pomalidomide-PEG2-N3;Pomalidomide-NH-CO-PEG2-N3;Pomalidomide-PEG2-azide/2267306-14-7;2-(2-(2-Azidoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide;Acetamide, 2-[2-(2-azidoethoxy)ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;2-(2-(2-Azidoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide?, Pomalidomide-PEG2-azide;2-(2-(2-Azidoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide, Crosslinker?E3 ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber: CB78118456
Molecular Formula: C19H20N6O7
Formula Weight: 444.4
MOL File: 2267306-14-7.mol

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Pomalidomide-PEG2-N3 Property

Melting point:: 188 °C
storage temp.: 2-8°C
solubility: DMSO: 90 mg/mL (202.52 mM)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 903833
Product name: Pomalidomide-PEG2-azide
Packaging: 50MG
Price: $647.5
Updated: 2025/07/31

Iris Biotech GmbH

Product number: PTC1530
Product name: Pomalidomid-PEG2-N3
Packaging: 50mg
Price: $607.5
Updated: 2021/12/16

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Pomalidomide-PEG2-N3 Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-PEG2-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

reaction suitability

reaction type: click chemistry
reagent type: ligand-linker conjugate

IC 50

Cereblon

Pomalidomide-PEG2-N3 Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomalidomide-PEG2-N3 Suppliers

China 21 United States 1 Global 22

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1615
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Shaanxi borno biotechnology co., LTD

Tel: +86-13759708231
Email: asherw9@hotmail.com
Country: China
ProdList: 2373
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Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Zhengzhou Converging Chemical Co. LTD

Tel: 0371-53399770 18037166334
Email: 2853031800@qq.com
Country: China
ProdList: 5872
Advantage: 58

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View Lastest Price from Pomalidomide-PEG2-N3 manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-NH-CO-PEG2-N3 2267306-14-7
Price: US $0.00/mg
Min. Order: 500mg
Purity: >99.00%
Supply Ability: 500mg
Release date: 2024-04-01

2267306-14-7, Pomalidomide-PEG2-N3Related Search:

Pomalidomide-PEG1-azide Pomalidomide-PEG3-N3 E3 ligase Ligand-Linker Conjugates 50 Pomalidomide-PEG3-CO2H Pomalidomide-PEG4-azide E3 Ligase Ligand-Linker Conjugates 22 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-PEG4-CO2H E3 Ligase Ligand-Linker Conjugates 1 POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG5-CO2H POMALIDOMIDE-PEG1-CO2H Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG6-butyl iodide Pomalidomide-PEG2-butyl iodide Pomalidomide-NH-CO-PEG6-N3 Pomalidomide-PEG5-N3

Pomalidomide-PEG2-N3

Pomalidomide-NH-CO-PEG2-N3

2-(2-(2-Azidoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide, Crosslinker?E3 ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader

N3-PEG2-CH2CO-Poma

Acetamide, 2-[2-(2-azidoethoxy)ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

2-(2-(2-Azidoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide?, Pomalidomide-PEG2-azide

2-(2-(2-Azidoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide

Pomalidomide-PEG2-azide/2267306-14-7

2267306-14-7