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Pomalidomide-PEG5-CO2H

Product Name
Pomalidomide-PEG5-CO2H
CAS No.
2139348-63-1
Chemical Name
Pomalidomide-PEG5-CO2H
Synonyms
Pomalidomide-PEG5-COOH;Pomalidomide-PEG5-CO2H;POMALIDOMIDE-PEG 5-CO 2 H;Pomalidomide 4'-PEG5-acid;Thalidomide-NH-PEG5-C2-COOH;Pomalidomide-PEG5-CO2H >=98%;Pomalidomide-PEG5-CO2H ISO 9001：2015 REACH;1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12,15-pentaoxaoctadecan-18-oic Acid;1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid;1-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
CBNumber
CB14846412
Molecular Formula
C26H35N3O11
Formula Weight
565.57
MOL File
2139348-63-1.mol
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Pomalidomide-PEG5-CO2H Property

Boiling point:
791.0±60.0 °C(Predicted)
Density 
1.360±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.28±0.10(Predicted)
form 
Solid-Liquid Mixture
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901828
Product name
Pomalidomide-PEG5-CO2H
Purity
≥95%
Packaging
50MG
Price
$269.2
Updated
2024/03/01
Tocris
Product number
7095
Product name
Pomalidomide4'-PEG5-acid
Purity
≥95%(HPLC)
Packaging
25
Price
$269
Updated
2021/12/16
Iris Biotech GmbH
Product number
PTC1190
Product name
Pomalidomide-PEG5-COOH
Packaging
50mg
Price
$594
Updated
2021/12/16
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Pomalidomide-PEG5-CO2H Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-PEG5-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

reaction suitability

reactivity: amine reactive
reagent type: ligand-linker conjugate

storage

Store at -20°C

Pomalidomide-PEG5-CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomalidomide-PEG5-CO2H Suppliers

China 31 India 1 United States 2 Global 34
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 18021050169
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021-50323701
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market@aladdin-e.com
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China
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Mashilabs (Shanghai) Co.,Ltd.
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19916721580
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QQ：3154870176
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mafarm@126.com
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China
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Sigma-Aldrich
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021-61415566 800-8193336
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orderCN@merckgroup.com
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 18892239720
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010-60605840
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psaitong@jm-bio.com
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China
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12306
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Xi'an Confluore Biological Technology Co., Ltd.
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+86-156-80926068 +86-15680926068
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1924344760@qq.com
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China
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4825
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58
Henan Alfachem Co.,Ltd.
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0371-0371-55051623 18137891487
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QQ：2853979817
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2853979817@qq.com
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Jiangsu aikang biomedical research and development co., LTD
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025-66110311 13155353615
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qzhang@aikonchem.com
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China
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Jilin Province Woda Biotechnology Co., Ltd.
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13504435624
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1927928688@qq.com
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China
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Henan Alfa Chemical Co., Ltd
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Dideu Industries Group Limited
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+86-29-89586680 +86-15129568250
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1026@dideu.com
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Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
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025-86755008 17751752005
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025-86755228
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hszhang@bestfluorodrug.com
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China
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Shanghai Kaiwei Chemical Technology Co., Ltd.
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021-58461859 15821823057
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service@aiviche.com
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Energy Chemical
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021-58432009 400-005-6266
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021-58436166
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marketing1@energy-chemical.com
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China
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Shandong Territorial sea Biological Technology Co., LTD
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15092083467
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18660263263@163.com
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Shanghai Haohong Pharmaceutical Co., Ltd.
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400-8210725 4008210725
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malulu@leyan.com
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Bide Pharmatech Ltd.
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400-1647117 13681763483
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product02@bidepharm.com
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Xi'an Qiyue Biotechnology Co., Ltd.
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400-400-6966-012-012 17778955912
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2957605606@qq.com
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Shanghai Huici Pharmaceutical Technology Co., LTD
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19372841038 19372841038
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lixing@pharmahuici.com
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CHO Chemical Materials Chang Zhou CO., LTD
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purchase@chochem.cn
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Changzhou Bojia Biomedical Technology Co., Ltd.
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czbjpharma@126.com
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ShenZhen Trendseen Biological Technology Co.,Ltd.
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13417589054 13417589054
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trendseenbio@gmail.com
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Shanghai Easy CDMO Co.,Ltd
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021-61734564
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Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
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CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD
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Accela ChemBio Co.,Ltd.
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syeu@accelachem.com
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Nanjing Bic Biotechnology Co., Ltd
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025-58906079 17352406906
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sales@bicbiotech.com
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Jilin Chinese Academy of Sciences-yanshen Technology
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18143011203
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ET-market@chemextension.com
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R&D Systems, Inc
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Xian confluore Biological Technology Co., Ltd.
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Nanjing Bicbiotechnology Co., Ltd
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LEAPCHEM CO., LTD.
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View Lastest Price from Pomalidomide-PEG5-CO2H manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Pomalidomide-PEG5-COOH 2139348-63-1
Price
US $0.00/mg
Min. Order
250mg
Purity
>99.00%
Supply Ability
250mg
Release date
2024-04-01

2139348-63-1, Pomalidomide-PEG5-CO2HRelated Search:

Pomalidomide-PEG3-CO2H E3 Ligase Ligand-Linker Conjugates 1 POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG1-azide Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG3-N3 Pomalidomide-PEG6-butyl iodide POMALIDOMIDE-PEG1-CO2H Pomalidomide-PEG3-Amine HCl salt Pomalidomide-PEG4-CO2H 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione E3 Ligase Ligand-Linker Conjugates 22 Pomalidomide-PEG2-butyl iodide Pomalidomide-PEG4-azide Pomalidomide-PEG2-N3 E3 ligase Ligand-Linker Conjugates 50 POMALIDOMIDE-PEG1-ALKYNE

  • POMALIDOMIDE-PEG 5-CO 2 H
  • Pomalidomide-PEG5-CO2H
  • Propanoic acid, 3-[[14-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12-tetraoxatetradec-1-yl]oxy]-
  • Pomalidomide-PEG5-CO2H >=98%
  • Pomalidomide-PEG5-COOH
  • Pomalidomide-PEG5-CO2H ISO 9001：2015 REACH
  • Pomalidomide 4'-PEG5-acid
  • 1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
  • Thalidomide-NH-PEG5-C2-COOH
  • 1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12,15-pentaoxaoctadecan-18-oic Acid
  • 1-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
  • 2139348-63-1
  • peg