2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID

Product Name: 2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID
CAS No.: 858956-25-9
Chemical Name: 2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID
Synonyms: 2-cyclopropyl-6-hydroxypyriMidine-4-carboxylic acid;2-Cyclopropyl-1,6-dihydro-6-oxo-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylicacid, 2-cyclopropyl-1,6-dihydro-6-oxo-;2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID;2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID ISO 9001：2015 REACH
CBNumber: CB9838217
Molecular Formula: C8H8N2O3
Formula Weight: 180.16
MOL File: 858956-25-9.mol

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2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID Property

Density: 1.70±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: 2-8°C
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C999033
Product name: 2-Cyclopropyl-6-hydroxypyrimidine-4-carboxylicAcid
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC141915
Product name: 2-Cyclopropyl-6-hydroxypyrimidine-4-carboxylic acid
Packaging: 250mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC141915
Product name: 2-Cyclopropyl-6-hydroxypyrimidine-4-carboxylic acid
Packaging: 500mg
Price: $190
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC141915
Product name: 2-Cyclopropyl-6-hydroxypyrimidine-4-carboxylic acid
Packaging: 1g
Price: $331.25
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0372079
Product name: 2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $505.77
Updated: 2021/12/16

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2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

57297-29-7

40876-98-0

858956-25-9

GENERAL STEPS: An aqueous solution (3 mL) of sodium hydroxide (2.85 g, 71.3 mmol) was slowly added to an aqueous solution (50 mL) of diethyl oxalacetate sodium salt (8.7 g, 50 mmol) under stirring conditions with continuous stirring for 20 minutes. Subsequently, cyclopropanecarboxamidine hydrochloride (5.0 g, 40 mmol) was added to the reaction system and the mixture was heated to 70 °C and kept reacting overnight. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted to 1 by careful dropwise addition of concentrated hydrochloric acid.The precipitated solid was separated by filtration and dried to afford 2-cyclopropyl-6-hydroxypyrimidine-4-carboxylic acid (4.7 g, 63% yield). The product was characterized as follows: 1H NMR (400 MHz, d6-DMSO) δH 13.3 (1H, br s), 12.97 (1H, br s), 6.59 (1H, s), 1.94 (1H, quintuple peak), 1.04 (4H, m) ppm.

References

[1] Patent: WO2009/81112, 2009, A2. Location in patent: Page/Page column 114
[2] Patent: WO2010/92339, 2010, A1. Location in patent: Page/Page column 83-84

2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID Suppliers

China 35 Germany 1 India 1 United Kingdom 2 United States 6 Global 45

Energy Chemical

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Email: sales8178@energy-chemical.com
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Shanghai Xiannuo Biotechnology Co., Ltd.

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Shanghai Carlow Chemicals Co., Ltd.

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Shanghai HuanChuan Industry Co.,Ltd.

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Nova(Shanghai) Pharmaceutical Co.,Ltd

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NovoChemy Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Amadis Chemical Company Limited

Tel: 571-89925085
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Nanjing KaiMubo Pharmaceutical Co., Ltd.

Tel: 025-66162170
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View Lastest Price from 2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID manufacturers

Dideu Industries Group Limited

Product: 2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID 858956-25-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-10

Career Henan Chemical Co

Product: 2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID 858956-25-9
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100g , 1kg, 5kg , 50kg
Release date: 2020-01-07

858956-25-9, 2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACIDRelated Search:

CYCLOPROPANECARBOXAMIDINE 2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID 5-CHLORO-2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID 4-Pyrimidinecarboxylic acid, 1,6-dihydro-2-methyl-6-oxo- 6-Oxo-3H-pyrimidine-4-carboxylic acid

2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID

2-Cyclopropyl-1,6-dihydro-6-oxo-4-pyrimidinecarboxylic acid

4-Pyrimidinecarboxylicacid, 2-cyclopropyl-1,6-dihydro-6-oxo-

2-cyclopropyl-6-hydroxypyriMidine-4-carboxylic acid

2-CYCLOPROPYL-6-OXO-1,6-DIHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID ISO 9001：2015 REACH

858956-25-9