1H-INDOL-1-AMINE
- Product Name
- 1H-INDOL-1-AMINE
- CAS No.
- 53406-38-5
- Chemical Name
- 1H-INDOL-1-AMINE
- Synonyms
- indol-1-amine;1-Aminoindole;Indol-1-ylaMine;1H-INDOL-1-AMINE;1H-INDOL-1-AMINE ISO 9001：2015 REACH
- CBNumber
- CB9838338
- Molecular Formula
- C8H8N2
- Formula Weight
- 132.16
- MOL File
- 53406-38-5.mol
1H-INDOL-1-AMINE Property
- Melting point:
- 40 °C
- Boiling point:
- 296.2±23.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- solid
- pka
- 7.05±0.70(Predicted)
- color
- Brown
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A615673
- Product name
- 1-Aminoindole
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 119383
- Product name
- 1-Aminoindole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- OR928208
- Product name
- 1H-Indol-1-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $170
- Updated
- 2021/12/16
- Product number
- Z4839
- Product name
- 1-Aminoindole
- Packaging
- 5g
- Price
- $249
- Updated
- 2021/12/16
- Product number
- 3H30-1-PT
- Product name
- 1H-Indol-1-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $272
- Updated
- 2021/12/16
1H-INDOL-1-AMINE Chemical Properties,Usage,Production
Synthesis Reference(s)
Tetrahedron Letters, 15, p. 461, 1974 DOI: 10.1016/S0040-4039(01)82243-7
Synthesis
120-72-9
2950-43-8
53406-38-5
General procedure for the synthesis of 1-aminoindole from indole and hydroxylamine sulfonic acid: refer to Example 4. 24.55 g (440 mmol) of potassium hydroxide, 3.201 g (27.3 mmol) of 1H-indole, and 6.15 g (54.4 mmol) of hydroxylamine-O-sulfonic acid were added slowly with stirring to 50 mL of N,N-dimethylformamide. After stirring the reaction mixture for 1 hour at room temperature, 50 mL of water was added and extracted three times with 100 mL of benzene. The combined organic phases were washed with water, dried and concentrated under reduced pressure. The residue was purified by silica gel column chromatography using 50% dichloromethane/hexane as eluent to give 1.16 g of the target product 1-aminoindole in 32% yield. Melting point: 41°C~41.5°C. 1H NMR (CDCl3, δ): 4.73 (br, 2H, NH2), 6.37 (d, 1H), 7.01~7.65 (m, 5H, phenyl ring).
References
[1] Organic Process Research and Development, 2011, vol. 15, # 3, p. 704 - 709
[2] Patent: US5336673, 1994, A
1H-INDOL-1-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
1H-INDOL-1-AMINE Suppliers
- Tel
- --
- Fax
- --
- Country
- India
- ProdList
- 128
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 1H-INDOL-1-AMINE manufacturers
- Product
- 1H-INDOL-1-AMINE 53406-38-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 814
- Release date
- 2019-09-02