3-BROMO-2-METHYL-5-NITROPYRIDINE

Product Name: 3-BROMO-2-METHYL-5-NITROPYRIDINE
CAS No.: 186593-42-0
Chemical Name: 3-BROMO-2-METHYL-5-NITROPYRIDINE
Synonyms: 3-Bromo-5-Nitro-2-Picoline;3-Bromo-2-methyl-5-nitrop...;2-Methyl-3-broMo-5-nitropyridine;3-BROMO-2-METHYL-5-NITROPYRIDINE;Pyridine, 3-bromo-2-methyl-5-nitro-;3-Bromo-2-methyl-5-nitropyridine 98%;3-BROMO-2-METHYL-5-NITROPYRIDINE ISO 9001：2015 REACH
CBNumber: CB9838772
Molecular Formula: C6H5BrN2O2
Formula Weight: 217.02
MOL File: 186593-42-0.mol

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3-BROMO-2-METHYL-5-NITROPYRIDINE Property

Boiling point:: 270.6±35.0 °C(Predicted)
Density: 1.709±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: -0.44±0.20(Predicted)
Appearance: Yellow to brown Solid
InChI: InChI=1S/C6H5BrN2O2/c1-4-6(7)2-5(3-8-4)9(10)11/h2-3H,1H3
InChIKey: QWAOQTGMEGSRLN-UHFFFAOYSA-N
SMILES: C1(C)=NC=C([N+]([O-])=O)C=C1Br

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B405183
Product name: 3-Bromo-2-methyl-5-nitropyridine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

ChemScene

Product number: CS-W019914
Product name: 3-Bromo-2-methyl-5-nitropyridine
Purity: >98.0%
Packaging: 10g
Price: $64
Updated: 2021/12/16

Matrix Scientific

Product number: 068772
Product name: 3-Bromo-2-methyl-5-nitro-pyridine
Purity: >95%
Packaging: 1g
Price: $68
Updated: 2021/12/16

ChemScene

Product number: CS-W019914
Product name: 3-Bromo-2-methyl-5-nitropyridine
Purity: >98.0%
Packaging: 5g
Price: $38
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H54-9-16
Product name: 3-Bromo-2-methyl-5-nitropyridine
Packaging: 1g
Price: $88
Updated: 2021/12/16

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3-BROMO-2-METHYL-5-NITROPYRIDINE Chemical Properties,Usage,Production

Synthesis

5470-17-7

105-53-3

186593-42-0

Step 3: NaH (60% oil dispersion, 2.32 g, 58 mmol) was slowly added to a solution of diethyl malonate (8.8 mL, 58 mmol) ether (110 mL) cooled to 15 °C over 5 min. Subsequently, 3-bromo-2-chloro-5-nitropyridine (12.5 g, 52.6 mmol) was added in four batches over a period of 15 min, and the temperature was observed to rise to 26 °C during the reaction. Upon completion of the reaction, the ether was removed by distillation under reduced pressure to give a red oily substance. This oily substance was stirred at 114 °C for 1 h 15 min and then 6 M H2SO4 (67 mL) was added. The mixture was heated to reflux for 8 h. After cooling to 0 °C, the pH was adjusted to 7 with 25% aqueous KOH (135 mL). The mixture was stirred in an ice bath for 25 min, the crude product was collected by filtration and washed with 50 mL of water. The crude product was dissolved in CH2Cl2 (350 mL), stirred for 30 min and filtered to remove insoluble material. The organic layer was dried with Na2SO4, filtered and concentrated to give 11.1 g of impure red oily product. This oily product was dissolved in CH2Cl2 (100 mL) and hexane (200 mL), filtered and the organic phase was concentrated to give 9.3 g of 3-bromo-2-methyl-5-nitropyridine as an orange crystalline solid in 81% yield.1H NMR (CDCl3) δ 9.25 (d, J = 2.3 Hz, 1H), 8.61 (d, J = 2.3 Hz, 1H), 2.80 (s, 3H).

References

[1] Patent: US2006/79522, 2006, A1. Location in patent: Page/Page column 8; 13
[2] Patent: US2006/79523, 2006, A1. Location in patent: Page/Page column 9; 13-14
[3] Patent: US2006/79524, 2006, A1. Location in patent: Page/Page column 13
[4] Patent: US2006/79683, 2006, A1. Location in patent: Page/Page column 8; 12
[5] Patent: CN103130792, 2016, B. Location in patent: Paragraph 0722-0724

3-BROMO-2-METHYL-5-NITROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-2-METHYL-5-NITROPYRIDINE Suppliers

China 110 Germany 1 India 6 Switzerland 1 United Kingdom 3 United States 11 Global 132

Synchem OHG

Tel: +49 5662 408730
Fax: +49 5662 4087320
Email: info@synchem.de
Country: Germany
ProdList: 4705
Advantage: 70

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View Lastest Price from 3-BROMO-2-METHYL-5-NITROPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 3-BROMO-2-METHYL-5-NITROPYRIDINE 186593-42-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-22

Career Henan Chemical Co

Product: 3-BROMO-2-METHYL-5-NITROPYRIDINE 186593-42-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-20

186593-42-0, 3-BROMO-2-METHYL-5-NITROPYRIDINERelated Search:

2-Amino-5-bromo-4-methyl-3-nitropyridine 98%,2-AMINO-5-BROMO-4-METHYL-3-NITROPYRIDINE 2-BROMO-6-METHYL-3-NITROPYRIDINE 2-Bromo-5-methyl-3-nitropyridine,2-BROMO-3-NITRO-5-PICOLINE (2-BROMO-5-METHYL-3-NITROPYRIDINE) 2-BROMO-5-NITRO-4-PICOLINE (2-BROMO-4-METHYL-5-NITROPYRIDINE),2-BROMO-4-METHYL-5-NITROPYRIDINE 2-BROMO-3-NITRO-4-PICOLINE (2-BROMO-4-METHYL-3-NITROPYRIDINE) 2-BROMO-6-METHYL-5-NITROPYRIDINE 5-Bromo-4-methyl-N-nitropyridine-2-amine 2-Bromo-6-methyl-4-nitropyridine ,97% 2-BROMO-3-METHYL-5-NITROPYRIDINE 2-BROMO-5-METHYL-4-NITROPYRIDINE 2-Chloro-3-Nitro-5-Bromo-6-Picoline 5-BROMO-2-HYDROXY-3-NITRO-6-PICOLINE 3-BROMO-2,6-DIMETHYL-5-NITROPYRIDIN-4-OL 2-Amino-5-bromo-6-methyl-3-nitropyridine 2-Amino-3-nitro-4,6-dimethyl-5-bromopyridine 3-BROMO-2-METHYL-5-NITROPYRIDINE 2-Amino-3-bromo-6-methyl-5-nitropyridine 3-Bromo-5-methyl-2-nitropyridine

3-BROMO-2-METHYL-5-NITROPYRIDINE

3-Bromo-5-Nitro-2-Picoline

3-Bromo-2-methyl-5-nitrop...

2-Methyl-3-broMo-5-nitropyridine

3-Bromo-2-methyl-5-nitropyridine 98%

Pyridine, 3-bromo-2-methyl-5-nitro-

3-BROMO-2-METHYL-5-NITROPYRIDINE ISO 9001：2015 REACH

186593-42-0

186493-42-0

Heterocycle-Pyridine series