D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL

Product Name: D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL
CAS No.: 109836-82-0
Chemical Name: D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL
Synonyms: D-threo-PDMP;D-THREO-PDMP HCL;D-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol;D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL;Decanamide, N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-;N-[(1R,2R)-1-Hydroxy-3-(4-morpholinyl)-1-phenyl-2-propanyl]decanamide hydrochloride;D-threo-1-Phenyl-2-DecanoylaMino-3-Morpholino-1-Propanol Hydrochloride (D-threo-PDMP)
CBNumber: CB9841569
Molecular Formula: C23H38N2O3
Formula Weight: 390.56
MOL File: 109836-82-0.mol

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D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL Chemical Properties,Usage,Production

Uses

D-threo-PDMP is a potent glucoceramide synthase (GCS) inhibitor, which reduces the glycosphingolipids on the cell surface by inhibiting glycosylation, reduces the total length of the axon plexus and the number of axon branch points, and inhibits neurite growth[1][2].

References

[1] Carmen García-Ruiz, et al. Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice. J Clin Invest. 2003 Jan;111(2):197-208. DOI:10.1172/JCI16010
[2] Dong Hoon Kwak, et al. Ganglioside GM3 inhibits the high glucose- and TGF-beta1-induced proliferation of rat glomerular mesangial cells. Life Sci. 2005 Sep 30;77(20):2540-51. DOI:10.1016/j.lfs.2005.01.034

D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL Preparation Products And Raw materials

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D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL Suppliers

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109836-82-0, D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCLRelated Search:

D,L-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL D-THREO-1-PHENYL-2-HEXADECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL 4-(2-aminopropyl)morpholine (-)-Pseudoephedrine D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL D,L-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL

N-[(1R,2R)-1-Hydroxy-3-(4-morpholinyl)-1-phenyl-2-propanyl]decanamide hydrochloride

D-THREO-PDMP HCL

D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL

D-threo-1-Phenyl-2-DecanoylaMino-3-Morpholino-1-Propanol Hydrochloride (D-threo-PDMP)

D-threo-PDMP

D-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol

Decanamide, N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-

109836-82-0

C23H38N2O3HCl