1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

Product Name: 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CAS No.: 869497-75-6
Chemical Name: 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
Synonyms: VUF 6002;VUF6002 maleate;VUF 6002 maleate;JNJ 10191584 MALEATE;JNJ 10191584 maleate salt;JNJ 10191584 maleate (VUF 6002);1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CBNumber: CB9844434
Molecular Formula: C17H19ClN4O5
Formula Weight: 394.80956
MOL File: 869497-75-6.mol

More

Less

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Property

storage temp.: Desiccate at RT
solubility: DMSO: ≥10mg/mL
form: powder
color: off-white to light tan

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: J3830
Product name: JNJ 10191584 maleate salt
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $105
Updated: 2022/05/15

Sigma-Aldrich

Product number: J3830
Product name: JNJ 10191584 maleate salt
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $573
Updated: 2022/05/15

Alfa Aesar

Product number: J65433
Product name: JNJ 10191584 maleate
Packaging: 10mg
Price: $57.2
Updated: 2021/12/16

Alfa Aesar

Product number: J65433
Product name: JNJ 10191584 maleate
Packaging: 50mg
Price: $229
Updated: 2021/12/16

Tocris

Product number: 2441
Product name: JNJ 10191584 maleate
Purity: ≥99%(HPLC)
Packaging: 10
Price: $152
Updated: 2021/12/16

More

Less

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Chemical Properties,Usage,Production

Uses

A highly selective histamine H4 receptor silent antagonist

Biological Activity

Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM) and is > 540-fold selective over the H 3 receptor (K i = 14.1 μ M). In vitro, inhibits mast cell and eosinophil chemotaxis with IC 50 values of 138 and 530 nM respectively. Orally active in vivo .

storage

room temperature (desiccate)

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Suppliers

China 18 Germany 2 United Kingdom 2 United States 7 Global 29

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Ascent Scientific

Tel: 4401179829988
Fax: 4402030 700 369
Email: customerservice@ascentscientific.co.uk
Country: United Kingdom
ProdList: 279
Advantage: 60

VDM Biochemicals

Tel: 0330-2528181
Fax: 0330-2528171
Email: sales@vdmbio.com
Country: United States
ProdList: 510
Advantage: 64

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4566
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8012
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7296
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1925
Advantage: 55

869497-75-6, 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATERelated Search:

(6-CHLORO-1H-BENZOIMIDAZOL-2-YL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE 1H-BENZIMIDAZOLE-2-CARBOXALDEHYDE, 5-CHLORO-

JNJ 10191584 MALEATE

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

VUF 6002

JNJ 10191584 maleate salt

VUF 6002 maleate

VUF6002 maleate

JNJ 10191584 maleate (VUF 6002)

869497-75-6

C13H15ClN4OC4H4O4

Other Enzyme Inhibitors and Activators.

Histamine

Other enzyme inhibitors and activators

Histamine receptor