1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

Product Name: 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CAS No.: 869497-75-6
Chemical Name: 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
Synonyms: VUF 6002;VUF6002 maleate;VUF 6002 maleate;JNJ 10191584 MALEATE;JNJ 10191584 maleate salt;JNJ 10191584 maleate (VUF 6002);JNJ 10191584 maleate (VUF 6002), Selective H4 antagonist;1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CBNumber: CB9844434
Molecular Formula: C17H19ClN4O5
Formula Weight: 394.80956
MOL File: 869497-75-6.mol

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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Property

storage temp.: Desiccate at RT
solubility: DMSO: ≥10mg/mL
form: powder
color: off-white to light tan

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: J3830
Product name: JNJ 10191584 maleate salt
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $105
Updated: 2022/05/15

Sigma-Aldrich

Product number: J3830
Product name: JNJ 10191584 maleate salt
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $573
Updated: 2022/05/15

Alfa Aesar

Product number: J65433
Product name: JNJ 10191584 maleate
Packaging: 50mg
Price: $229
Updated: 2021/12/16

Alfa Aesar

Product number: J65433
Product name: JNJ 10191584 maleate
Packaging: 10mg
Price: $57.2
Updated: 2021/12/16

Tocris

Product number: 2441
Product name: JNJ 10191584 maleate
Purity: ≥99%(HPLC)
Packaging: 10
Price: $152
Updated: 2021/12/16

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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Chemical Properties,Usage,Production

Uses

A highly selective histamine H4 receptor silent antagonist

Biological Activity

Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM) and is > 540-fold selective over the H 3 receptor (K i = 14.1 μ M). In vitro, inhibits mast cell and eosinophil chemotaxis with IC 50 values of 138 and 530 nM respectively. Orally active in vivo .

storage

room temperature (desiccate)

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Suppliers

China 18 Germany 2 United Kingdom 2 United States 8 Global 30

J & K SCIENTIFIC LTD.

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869497-75-6, 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATERelated Search:

(6-CHLORO-1H-BENZOIMIDAZOL-2-YL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE 1H-BENZIMIDAZOLE-2-CARBOXALDEHYDE, 5-CHLORO-

JNJ 10191584 MALEATE

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

VUF 6002

JNJ 10191584 maleate salt

VUF 6002 maleate

VUF6002 maleate

JNJ 10191584 maleate (VUF 6002)

JNJ 10191584 maleate (VUF 6002), Selective H4 antagonist

869497-75-6

C13H15ClN4OC4H4O4

Other Enzyme Inhibitors and Activators.

Histamine

Other enzyme inhibitors and activators

Histamine receptor