ChemicalBook > CAS DataBase List > 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

Product Name
1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CAS No.
869497-75-6
Chemical Name
1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
Synonyms
VUF 6002;VUF6002 maleate;VUF 6002 maleate;JNJ 10191584 MALEATE;JNJ 10191584 maleate salt;JNJ 10191584 maleate (VUF 6002);1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CBNumber
CB9844434
Molecular Formula
C17H19ClN4O5
Formula Weight
394.80956
MOL File
869497-75-6.mol
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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Property

storage temp. 
Desiccate at RT
solubility 
DMSO: ≥10mg/mL
form 
powder
color 
off-white to light tan
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
J3830
Product name
JNJ 10191584 maleate salt
Purity
≥98% (HPLC)
Packaging
5mg
Price
$105
Updated
2022/05/15
Sigma-Aldrich
Product number
J3830
Product name
JNJ 10191584 maleate salt
Purity
≥98% (HPLC)
Packaging
25mg
Price
$573
Updated
2022/05/15
Alfa Aesar
Product number
J65433
Product name
JNJ 10191584 maleate
Packaging
50mg
Price
$229
Updated
2021/12/16
Alfa Aesar
Product number
J65433
Product name
JNJ 10191584 maleate
Packaging
10mg
Price
$57.2
Updated
2021/12/16
Tocris
Product number
2441
Product name
JNJ 10191584 maleate
Purity
≥99%(HPLC)
Packaging
10
Price
$152
Updated
2021/12/16
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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Chemical Properties,Usage,Production

Uses

A highly selective histamine H4 receptor silent antagonist

Biological Activity

Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM) and is > 540-fold selective over the H 3 receptor (K i = 14.1 μ M). In vitro, inhibits mast cell and eosinophil chemotaxis with IC 50 values of 138 and 530 nM respectively. Orally active in vivo .

storage

room temperature (desiccate)

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Suppliers

China 17 Germany 2 United Kingdom 2 United States 7 Global 28
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
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69
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4196
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8019
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62
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9854
Advantage
58
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1836
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Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10522
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58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8141
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58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
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China
ProdList
44941
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58
Shanghai Universal Biotech Co.,Ltd
Tel
18768175414
Email
gaojun@univ-bio.com
Country
China
ProdList
24998
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58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
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24017
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Aikon International Limited
Tel
18626450290
Email
yftan@aikonchem.com
Country
China
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10718
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Nanjing Tengyi Biotechnology Co., Ltd
Tel
025-58851786 17714337195
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sales@tybiochem.com
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China
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5447
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58
https://hanhongsci.com/
Tel
021-54306202 18917919676
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info@hanhongsci.com
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China
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29990
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58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
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market@aladdin-e.com
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China
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48467
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58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
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+86 21 5161 9052/ 5187 7796
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ivan@atkchemical.com
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China
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32715
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Wuhan Topule Biopharmaceutical Co., Ltd
Tel
+8618327326525
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masar@topule.com
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China
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8474
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58

869497-75-6, 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATERelated Search:

(6-CHLORO-1H-BENZOIMIDAZOL-2-YL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE 1H-BENZIMIDAZOLE-2-CARBOXALDEHYDE, 5-CHLORO-

  • JNJ 10191584 MALEATE
  • 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
  • VUF 6002
  • JNJ 10191584 maleate salt
  • VUF 6002 maleate
  • VUF6002 maleate
  • JNJ 10191584 maleate (VUF 6002)
  • 869497-75-6
  • C13H15ClN4OC4H4O4
  • Other Enzyme Inhibitors and Activators.
  • Histamine
  • Other enzyme inhibitors and activators
  • Histamine receptor