1-Boc-3-phenylpiperidin-4-one

Product Name: 1-Boc-3-phenylpiperidin-4-one
CAS No.: 632352-56-8
Chemical Name: 1-Boc-3-phenylpiperidin-4-one
Synonyms: tert-butyl 4-oxo-3-phenylpiperidine-1-carboxylate;1-Boc-3-phenyl-4-piperidone;1-BOC-3-PHENYL-PIPERIDIN-4-ONE;1-Boc-3-Phenylpiperidin-4-one 96%;1-Boc-3-phenylpiperidin-4-one, 97%min;tert-butyl 4-Oxo-3-phenylpiperidine-1-carboxylat;4-oxo-3-phenyl-1-piperidinecarboxylic acid tert-butyl ester;1-Piperidinecarboxylic acid, 4-oxo-3-phenyl-, 1,1-diMethylethyl ester
CBNumber: CB9847501
Molecular Formula: C16H21NO3
Formula Weight: 275.34
MOL File: 632352-56-8.mol

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1-Boc-3-phenylpiperidin-4-one Property

Melting point:: 93-94 °C
Boiling point:: 400.8±45.0 °C(Predicted)
Density: 1.122±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -2.03±0.40(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C16H21NO3/c1-16(2,3)20-15(19)17-10-9-14(18)13(11-17)12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3
InChIKey: SIZBVZFDWNCKJM-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC(=O)C(C2=CC=CC=C2)C1

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Safety

HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

aablocks

Product number: AA00E9MO
Product name: tert-Butyl 4-oxo-3-phenylpiperidine-1-carboxylate
Purity: 97%
Packaging: 100mg
Price: $14
Updated: 2026/05/28

aablocks

Product number: AA00E9MO
Product name: tert-Butyl 4-oxo-3-phenylpiperidine-1-carboxylate
Purity: 97%
Packaging: 250mg
Price: $30
Updated: 2026/05/28

aablocks

Product number: AA00E9MO
Product name: tert-Butyl 4-oxo-3-phenylpiperidine-1-carboxylate
Purity: 97%
Packaging: 1g
Price: $65
Updated: 2026/05/28

aablocks

Product number: AA00E9MO
Product name: tert-Butyl 4-oxo-3-phenylpiperidine-1-carboxylate
Purity: 97%
Packaging: 5g
Price: $232
Updated: 2026/05/28

aablocks

Product number: AA00E9MO
Product name: tert-Butyl 4-oxo-3-phenylpiperidine-1-carboxylate
Purity: 97%
Packaging: 10g
Price: $457
Updated: 2026/05/28

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1-Boc-3-phenylpiperidin-4-one Chemical Properties,Usage,Production

Synthesis

76041-09-3

24424-99-5

632352-56-8

To a solution of 3-phenylpiperidin-4-one (3.47 g) and triethylamine (2.76 ml) in acetonitrile (50 ml) prepared in Method 4 was added di-tert-butyl dicarbonate (6.55 g) and the reaction mixture was stirred for 14 hours at room temperature. After completion of the reaction, the mixture was poured into water and the product was extracted with ethyl acetate. The organic phase was washed sequentially with 10% aqueous citric acid and saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The crude product obtained was separated and purified by silica gel column chromatography (eluent: hexane/ethyl acetate=10:1) to give tert-butyl 4-oxo-3-phenylpiperidine-1-carboxylate as a white powder (3.90 g, 71% yield). The product can be used directly in the subsequent reaction without further purification.

References

[1] European Journal of Organic Chemistry, 2007, # 26, p. 4376 - 4382
[2] Patent: EP1553084, 2005, A1. Location in patent: Page/Page column 44

1-Boc-3-phenylpiperidin-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Boc-3-phenylpiperidin-4-one Suppliers

China 44 Germany 2 India 1 Switzerland 1 United Kingdom 1 United States 9 Global 58

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View Lastest Price from 1-Boc-3-phenylpiperidin-4-one manufacturers

Career Henan Chemical Co

Product: 1-Boc-3-phenylpiperidin-4-one 632352-56-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-23

632352-56-8, 1-Boc-3-phenylpiperidin-4-oneRelated Search:

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1-BOC-3-PHENYL-PIPERIDIN-4-ONE

tert-butyl 4-oxo-3-phenylpiperidine-1-carboxylate

1-Piperidinecarboxylic acid, 4-oxo-3-phenyl-, 1,1-diMethylethyl ester

tert-butyl 4-Oxo-3-phenylpiperidine-1-carboxylat

1-Boc-3-Phenylpiperidin-4-one 96%

4-oxo-3-phenyl-1-piperidinecarboxylic acid tert-butyl ester

1-Boc-3-phenyl-4-piperidone

1-Boc-3-phenylpiperidin-4-one, 97%min

632352-56-8